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DBNL (drebrin like)

Identity

Alias_namesdrebrin-like
Alias_symbol (synonym)SH3P7
HIP-55
ABP1
Other aliasHIP55
HGNC (Hugo) DBNL
LocusID (NCBI) 28988
Atlas_Id 55016
Location 7p13  [Link to chromosome band 7p13]
Location_base_pair Starts at 44044640 and ends at 44061716 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
BCAM (19q13.32) / DBNL (7p13)DBNL (7p13) / ATOX1 (5q33.1)DBNL (7p13) / COL4A2 (13q34)
DBNL (7p13) / DBNL (7p13)DBNL (7p13) / EEA1 (12q22)DBNL (7p13) / KIAA1549L (11p13)
EIF2AK1 (7p22.1) / DBNL (7p13)LITAF (16p13.13) / DBNL (7p13)NEK11 (3q22.1) / DBNL (7p13)
DBNL 7p13 / EEA1 12q22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DBNL   2696
Cards
Entrez_Gene (NCBI)DBNL  28988  drebrin like
AliasesABP1; HIP-55; HIP55; SH3P7
GeneCards (Weizmann)DBNL
Ensembl hg19 (Hinxton)ENSG00000136279 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000136279 [Gene_View]  chr7:44044640-44061716 [Contig_View]  DBNL [Vega]
ICGC DataPortalENSG00000136279
TCGA cBioPortalDBNL
AceView (NCBI)DBNL
Genatlas (Paris)DBNL
WikiGenes28988
SOURCE (Princeton)DBNL
Genetics Home Reference (NIH)DBNL
Genomic and cartography
GoldenPath hg38 (UCSC)DBNL  -     chr7:44044640-44061716 +  7p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DBNL  -     7p13   [Description]    (hg19-Feb_2009)
EnsemblDBNL - 7p13 [CytoView hg19]  DBNL - 7p13 [CytoView hg38]
Mapping of homologs : NCBIDBNL [Mapview hg19]  DBNL [Mapview hg38]
OMIM610106   
Gene and transcription
Genbank (Entrez)AB209486 AF077353 AF151364 AF197060 AF218020
RefSeq transcript (Entrez)NM_001014436 NM_001122956 NM_001284313 NM_001284315 NM_014063
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DBNL
Cluster EST : UnigeneHs.436500 [ NCBI ]
CGAP (NCI)Hs.436500
Alternative Splicing GalleryENSG00000136279
Gene ExpressionDBNL [ NCBI-GEO ]   DBNL [ EBI - ARRAY_EXPRESS ]   DBNL [ SEEK ]   DBNL [ MEM ]
Gene Expression Viewer (FireBrowse)DBNL [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)28988
GTEX Portal (Tissue expression)DBNL
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJU6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJU6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJU6
Splice isoforms : SwissVarQ9UJU6
PhosPhoSitePlusQ9UJU6
Domaine pattern : Prosite (Expaxy)ADF_H (PS51263)    SH3 (PS50002)   
Domains : Interpro (EBI)ADF-H    ADF-H/Gelsolin-like_dom    Dbnl    SH3_domain   
Domain families : Pfam (Sanger)Cofilin_ADF (PF00241)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam00241    pfam14604   
Domain families : Smart (EMBL)ADF (SM00102)  SH3 (SM00326)  
Conserved Domain (NCBI)DBNL
DMDM Disease mutations28988
Blocks (Seattle)DBNL
PDB (SRS)1X67   
PDB (PDBSum)1X67   
PDB (IMB)1X67   
PDB (RSDB)1X67   
Structural Biology KnowledgeBase1X67   
SCOP (Structural Classification of Proteins)1X67   
CATH (Classification of proteins structures)1X67   
SuperfamilyQ9UJU6
Human Protein AtlasENSG00000136279
Peptide AtlasQ9UJU6
HPRD06588
IPIIPI00456925   IPI00396437   IPI00101968   IPI01015887   IPI00924475   IPI00924490   IPI00910949   IPI01018888   IPI00925098   IPI00924873   IPI00925506   IPI01012957   IPI00926741   IPI00926516   IPI00927153   IPI01012501   IPI00947133   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJU6
IntAct (EBI)Q9UJU6
FunCoupENSG00000136279
BioGRIDDBNL
STRING (EMBL)DBNL
ZODIACDBNL
Ontologies - Pathways
QuickGOQ9UJU6
Ontology : AmiGOGolgi membrane  ruffle  podosome  adaptive immune response  actin binding  protein binding  extracellular region  cytoplasm  cytoplasm  early endosome  cytosol  plasma membrane  cell cortex  receptor-mediated endocytosis  activation of JUN kinase activity  synapse assembly  protein C-terminus binding  enzyme activator activity  postsynaptic density  Rac protein signal transduction  protein domain specific binding  lamellipodium  cell junction  dendrite  clathrin-coated vesicle membrane  secretory granule lumen  neutrophil degranulation  cadherin binding  neuron projection morphogenesis  actin filament binding  extracellular exosome  podosome assembly  ruffle assembly  tertiary granule lumen  ficolin-1-rich granule lumen  
Ontology : EGO-EBIGolgi membrane  ruffle  podosome  adaptive immune response  actin binding  protein binding  extracellular region  cytoplasm  cytoplasm  early endosome  cytosol  plasma membrane  cell cortex  receptor-mediated endocytosis  activation of JUN kinase activity  synapse assembly  protein C-terminus binding  enzyme activator activity  postsynaptic density  Rac protein signal transduction  protein domain specific binding  lamellipodium  cell junction  dendrite  clathrin-coated vesicle membrane  secretory granule lumen  neutrophil degranulation  cadherin binding  neuron projection morphogenesis  actin filament binding  extracellular exosome  podosome assembly  ruffle assembly  tertiary granule lumen  ficolin-1-rich granule lumen  
NDEx NetworkDBNL
Atlas of Cancer Signalling NetworkDBNL
Wikipedia pathwaysDBNL
Orthology - Evolution
OrthoDB28988
GeneTree (enSembl)ENSG00000136279
Phylogenetic Trees/Animal Genes : TreeFamDBNL
HOVERGENQ9UJU6
HOGENOMQ9UJU6
Homologs : HomoloGeneDBNL
Homology/Alignments : Family Browser (UCSC)DBNL
Gene fusions - Rearrangements
Fusion: TCGADBNL 7p13 EEA1 12q22 HNSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDBNL [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DBNL
dbVarDBNL
ClinVarDBNL
1000_GenomesDBNL 
Exome Variant ServerDBNL
ExAC (Exome Aggregation Consortium)DBNL (select the gene name)
Genetic variants : HAPMAP28988
Genomic Variants (DGV)DBNL [DGVbeta]
DECIPHERDBNL [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDBNL 
Mutations
ICGC Data PortalDBNL 
TCGA Data PortalDBNL 
Broad Tumor PortalDBNL
OASIS PortalDBNL [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDBNL  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDBNL
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DBNL
DgiDB (Drug Gene Interaction Database)DBNL
DoCM (Curated mutations)DBNL (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DBNL (select a term)
intoGenDBNL
Cancer3DDBNL(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610106   
Orphanet
MedgenDBNL
Genetic Testing Registry DBNL
NextProtQ9UJU6 [Medical]
TSGene28988
GENETestsDBNL
Huge Navigator DBNL [HugePedia]
snp3D : Map Gene to Disease28988
BioCentury BCIQDBNL
ClinGenDBNL
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD28988
Chemical/Pharm GKB GenePA27164
Clinical trialDBNL
Miscellaneous
canSAR (ICR)DBNL (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDBNL
EVEXDBNL
GoPubMedDBNL
iHOPDBNL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:12:45 CEST 2017

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