Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DBR1 (debranching RNA lariats 1)

Identity

Alias_namesdebranching enzyme (S. Cerevisiae) homolog 1
debranching enzyme homolog 1 (S. cerevisiae)
Other alias-
HGNC (Hugo) DBR1
LocusID (NCBI) 51163
Atlas_Id 62307
Location 3q22.3  [Link to chromosome band 3q22]
Location_base_pair Starts at 138160988 and ends at 138174949 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
ATR (3q23) / DBR1 (3q22.3)VPRBP (3p21.2) / DBR1 (3q22.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DBR1   15594
Cards
Entrez_Gene (NCBI)DBR1  51163  debranching RNA lariats 1
Aliases
GeneCards (Weizmann)DBR1
Ensembl hg19 (Hinxton)ENSG00000138231 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000138231 [Gene_View]  chr3:138160988-138174949 [Contig_View]  DBR1 [Vega]
ICGC DataPortalENSG00000138231
TCGA cBioPortalDBR1
AceView (NCBI)DBR1
Genatlas (Paris)DBR1
WikiGenes51163
SOURCE (Princeton)DBR1
Genetics Home Reference (NIH)DBR1
Genomic and cartography
GoldenPath hg38 (UCSC)DBR1  -     chr3:138160988-138174949 -  3q22.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DBR1  -     3q22.3   [Description]    (hg19-Feb_2009)
EnsemblDBR1 - 3q22.3 [CytoView hg19]  DBR1 - 3q22.3 [CytoView hg38]
Mapping of homologs : NCBIDBR1 [Mapview hg19]  DBR1 [Mapview hg38]
OMIM607024   
Gene and transcription
Genbank (Entrez)AF180919 AK000116 AK094147 AL702928 BC009472
RefSeq transcript (Entrez)NM_016216
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DBR1
Cluster EST : UnigeneHs.477700 [ NCBI ]
CGAP (NCI)Hs.477700
Alternative Splicing GalleryENSG00000138231
Gene ExpressionDBR1 [ NCBI-GEO ]   DBR1 [ EBI - ARRAY_EXPRESS ]   DBR1 [ SEEK ]   DBR1 [ MEM ]
Gene Expression Viewer (FireBrowse)DBR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)51163
GTEX Portal (Tissue expression)DBR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UK59   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UK59  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UK59
Splice isoforms : SwissVarQ9UK59
PhosPhoSitePlusQ9UK59
Domains : Interpro (EBI)Calcineurin-like_PHP_ApaH    DBR1_C    Metallo-depent_PP-like   
Domain families : Pfam (Sanger)DBR1 (PF05011)    Metallophos (PF00149)   
Domain families : Pfam (NCBI)pfam05011    pfam00149   
Domain families : Smart (EMBL)DBR1 (SM01124)  
Conserved Domain (NCBI)DBR1
DMDM Disease mutations51163
Blocks (Seattle)DBR1
SuperfamilyQ9UK59
Human Protein AtlasENSG00000138231
Peptide AtlasQ9UK59
HPRD07384
IPIIPI00305545   IPI00787976   IPI01013377   IPI00946473   
Protein Interaction databases
DIP (DOE-UCLA)Q9UK59
IntAct (EBI)Q9UK59
FunCoupENSG00000138231
BioGRIDDBR1
STRING (EMBL)DBR1
ZODIACDBR1
Ontologies - Pathways
QuickGOQ9UK59
Ontology : AmiGORNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  RNA binding  nucleus  RNA lariat debranching enzyme activity  metal ion binding  RNA phosphodiester bond hydrolysis, endonucleolytic  
Ontology : EGO-EBIRNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  RNA binding  nucleus  RNA lariat debranching enzyme activity  metal ion binding  RNA phosphodiester bond hydrolysis, endonucleolytic  
NDEx NetworkDBR1
Atlas of Cancer Signalling NetworkDBR1
Wikipedia pathwaysDBR1
Orthology - Evolution
OrthoDB51163
GeneTree (enSembl)ENSG00000138231
Phylogenetic Trees/Animal Genes : TreeFamDBR1
HOVERGENQ9UK59
HOGENOMQ9UK59
Homologs : HomoloGeneDBR1
Homology/Alignments : Family Browser (UCSC)DBR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDBR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DBR1
dbVarDBR1
ClinVarDBR1
1000_GenomesDBR1 
Exome Variant ServerDBR1
ExAC (Exome Aggregation Consortium)DBR1 (select the gene name)
Genetic variants : HAPMAP51163
Genomic Variants (DGV)DBR1 [DGVbeta]
DECIPHERDBR1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDBR1 
Mutations
ICGC Data PortalDBR1 
TCGA Data PortalDBR1 
Broad Tumor PortalDBR1
OASIS PortalDBR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDBR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDBR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DBR1
DgiDB (Drug Gene Interaction Database)DBR1
DoCM (Curated mutations)DBR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DBR1 (select a term)
intoGenDBR1
Cancer3DDBR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607024   
Orphanet
MedgenDBR1
Genetic Testing Registry DBR1
NextProtQ9UK59 [Medical]
TSGene51163
GENETestsDBR1
Target ValidationDBR1
Huge Navigator DBR1 [HugePedia]
snp3D : Map Gene to Disease51163
BioCentury BCIQDBR1
ClinGenDBR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD51163
Chemical/Pharm GKB GenePA27166
Clinical trialDBR1
Miscellaneous
canSAR (ICR)DBR1 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDBR1
EVEXDBR1
GoPubMedDBR1
iHOPDBR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:05:51 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.