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DCK (deoxycytidine kinase)

Identity

Other alias-
HGNC (Hugo) DCK
LocusID (NCBI) 1633
Atlas_Id 40270
Location 4q13.3  [Link to chromosome band 4q13]
Location_base_pair Starts at 70993548 and ends at 71030912 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DCK (4q13.3) / GRSF1 (4q13.3)FRAS1 (4q21.21) / DCK (4q13.3)RAPGEF1 (9q34.13) / DCK (4q13.3)
DCK 4q13.3 / GRSF1 4q13.3FRAS1 4q21.21 / DCK 4q13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DCK   2704
Cards
Entrez_Gene (NCBI)DCK  1633  deoxycytidine kinase
Aliases
GeneCards (Weizmann)DCK
Ensembl hg19 (Hinxton)ENSG00000156136 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156136 [Gene_View]  chr4:70993548-71030912 [Contig_View]  DCK [Vega]
ICGC DataPortalENSG00000156136
TCGA cBioPortalDCK
AceView (NCBI)DCK
Genatlas (Paris)DCK
WikiGenes1633
SOURCE (Princeton)DCK
Genetics Home Reference (NIH)DCK
Genomic and cartography
GoldenPath hg38 (UCSC)DCK  -     chr4:70993548-71030912 +  4q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCK  -     4q13.3   [Description]    (hg19-Feb_2009)
EnsemblDCK - 4q13.3 [CytoView hg19]  DCK - 4q13.3 [CytoView hg38]
Mapping of homologs : NCBIDCK [Mapview hg19]  DCK [Mapview hg38]
OMIM125450   
Gene and transcription
Genbank (Entrez)AK303292 AK313523 BC103764 BC114617 BI601939
RefSeq transcript (Entrez)NM_000788
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DCK
Cluster EST : UnigeneHs.709 [ NCBI ]
CGAP (NCI)Hs.709
Alternative Splicing GalleryENSG00000156136
Gene ExpressionDCK [ NCBI-GEO ]   DCK [ EBI - ARRAY_EXPRESS ]   DCK [ SEEK ]   DCK [ MEM ]
Gene Expression Viewer (FireBrowse)DCK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1633
GTEX Portal (Tissue expression)DCK
Protein : pattern, domain, 3D structure
UniProt/SwissProtP27707   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP27707  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP27707
Splice isoforms : SwissVarP27707
PhosPhoSitePlusP27707
Domains : Interpro (EBI)DCK/DGK    DNK_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)dNK (PF01712)   
Domain families : Pfam (NCBI)pfam01712   
Conserved Domain (NCBI)DCK
DMDM Disease mutations1633
Blocks (Seattle)DCK
PDB (SRS)1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
PDB (PDBSum)1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
PDB (IMB)1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
PDB (RSDB)1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
Structural Biology KnowledgeBase1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
SCOP (Structural Classification of Proteins)1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
CATH (Classification of proteins structures)1P5Z    1P60    1P61    1P62    2A2Z    2A30    2A7Q    2NO0    2NO1    2NO6    2NO7    2NO9    2NOA    2QRN    2QRO    2ZI3    2ZI4    2ZI5    2ZI6    2ZI7    2ZI9    2ZIA    3HP1    3IPX    3IPY    3KFX    3MJR    3QEJ    3QEN    3QEO    4JLJ    4JLK    4JLM    4JLN    4KCG    4L5B    4Q18    4Q19    4Q1A    4Q1B    4Q1C    4Q1D    4Q1E    4Q1F   
SuperfamilyP27707
Human Protein AtlasENSG00000156136
Peptide AtlasP27707
HPRD00507
IPIIPI00020454   IPI00964324   IPI00966824   IPI00965238   IPI00967117   
Protein Interaction databases
DIP (DOE-UCLA)P27707
IntAct (EBI)P27707
FunCoupENSG00000156136
BioGRIDDCK
STRING (EMBL)DCK
ZODIACDCK
Ontologies - Pathways
QuickGOP27707
Ontology : AmiGOdeoxycytidine kinase activity  ATP binding  nucleus  cytosol  pyrimidine nucleotide metabolic process  drug binding  deoxyribonucleoside monophosphate biosynthetic process  nucleotide biosynthetic process  phosphorylation  nucleoside kinase activity  protein homodimerization activity  pyrimidine nucleoside salvage  purine-containing compound salvage  
Ontology : EGO-EBIdeoxycytidine kinase activity  ATP binding  nucleus  cytosol  pyrimidine nucleotide metabolic process  drug binding  deoxyribonucleoside monophosphate biosynthetic process  nucleotide biosynthetic process  phosphorylation  nucleoside kinase activity  protein homodimerization activity  pyrimidine nucleoside salvage  purine-containing compound salvage  
Pathways : KEGGPurine metabolism    Pyrimidine metabolism   
NDEx NetworkDCK
Atlas of Cancer Signalling NetworkDCK
Wikipedia pathwaysDCK
Orthology - Evolution
OrthoDB1633
GeneTree (enSembl)ENSG00000156136
Phylogenetic Trees/Animal Genes : TreeFamDCK
HOVERGENP27707
HOGENOMP27707
Homologs : HomoloGeneDCK
Homology/Alignments : Family Browser (UCSC)DCK
Gene fusions - Rearrangements
Fusion : MitelmanDCK/GRSF1 [4q13.3/4q13.3]  
Fusion : MitelmanFRAS1/DCK [4q21.21/4q13.3]  [t(4;4)(q13;q21)]  
Fusion: TCGADCK 4q13.3 GRSF1 4q13.3 BRCA
Fusion: TCGAFRAS1 4q21.21 DCK 4q13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCK
dbVarDCK
ClinVarDCK
1000_GenomesDCK 
Exome Variant ServerDCK
ExAC (Exome Aggregation Consortium)DCK (select the gene name)
Genetic variants : HAPMAP1633
Genomic Variants (DGV)DCK [DGVbeta]
DECIPHERDCK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCK 
Mutations
ICGC Data PortalDCK 
TCGA Data PortalDCK 
Broad Tumor PortalDCK
OASIS PortalDCK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDCK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DCK
DgiDB (Drug Gene Interaction Database)DCK
DoCM (Curated mutations)DCK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCK (select a term)
intoGenDCK
Cancer3DDCK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM125450   
Orphanet
MedgenDCK
Genetic Testing Registry DCK
NextProtP27707 [Medical]
TSGene1633
GENETestsDCK
Huge Navigator DCK [HugePedia]
snp3D : Map Gene to Disease1633
BioCentury BCIQDCK
ClinGenDCK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1633
Chemical/Pharm GKB GenePA137
Clinical trialDCK
Miscellaneous
canSAR (ICR)DCK (select the gene name)
Probes
Litterature
PubMed93 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCK
EVEXDCK
GoPubMedDCK
iHOPDCK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Fri May 19 12:12:48 CEST 2017

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