Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DCN (decorin)

Identity

Other namesCSCD
DSPG2
PG40
PGII
PGS2
SLRR1B
HGNC (Hugo) DCN
LocusID (NCBI) 1634
Atlas_Id 40274
Location 12q21.33
Location_base_pair Starts at 91539035 and ends at 91576806 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DCN   2705
Cards
Entrez_Gene (NCBI)DCN  1634  decorin
GeneCards (Weizmann)DCN
Ensembl hg19 (Hinxton)ENSG00000011465 [Gene_View]  chr12:91539035-91576806 [Contig_View]  DCN [Vega]
Ensembl hg38 (Hinxton)ENSG00000011465 [Gene_View]  chr12:91539035-91576806 [Contig_View]  DCN [Vega]
ICGC DataPortalENSG00000011465
TCGA cBioPortalDCN
AceView (NCBI)DCN
Genatlas (Paris)DCN
WikiGenes1634
SOURCE (Princeton)DCN
Genomic and cartography
GoldenPath hg19 (UCSC)DCN  -     chr12:91539035-91576806 -  12q21.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DCN  -     12q21.33   [Description]    (hg38-Dec_2013)
EnsemblDCN - 12q21.33 [CytoView hg19]  DCN - 12q21.33 [CytoView hg38]
Mapping of homologs : NCBIDCN [Mapview hg19]  DCN [Mapview hg38]
OMIM125255   610048   
Gene and transcription
Genbank (Entrez)AF138300 AF138301 AF138302 AF138303 AF138304
RefSeq transcript (Entrez)NM_001920 NM_133503 NM_133504 NM_133505 NM_133506 NM_133507
RefSeq genomic (Entrez)NC_000012 NC_018923 NG_011672 NT_029419 NW_004929384
Consensus coding sequences : CCDS (NCBI)DCN
Cluster EST : UnigeneHs.530910 [ NCBI ]
CGAP (NCI)Hs.530910
Alternative Splicing : Fast-db (Paris)GSHG0007676
Alternative Splicing GalleryENSG00000011465
Gene ExpressionDCN [ NCBI-GEO ]     DCN [ SEEK ]   DCN [ MEM ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
BioGPS (Tissue expression)1634
Protein : pattern, domain, 3D structure
UniProt/SwissProtP07585 (Uniprot)
NextProtP07585  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP07585
Splice isoforms : SwissVarP07585 (Swissvar)
PhosPhoSitePlusP07585
Domaine pattern : Prosite (Expaxy)LRR (PS51450)   
Domains : Interpro (EBI)Decorin    Leu-rich_rpt    Leu-rich_rpt_typical-subtyp    LRR-contain_N    SLRP_I_decor/aspor/byglycan   
Domain families : Pfam (Sanger)LRR_8 (PF13855)    LRRNT (PF01462)   
Domain families : Pfam (NCBI)pfam13855    pfam01462   
Domain families : Smart (EMBL)LRR_TYP (SM00369)  LRRNT (SM00013)  
DMDM Disease mutations1634
Blocks (Seattle)DCN
Human Protein AtlasENSG00000011465
Peptide AtlasP07585
HPRD00501
IPIIPI00012119   IPI00219400   IPI00219401   IPI00219403   IPI00219404   IPI01022250   IPI01022113   IPI01021688   IPI01021543   IPI01021358   IPI01021491   IPI01021132   IPI01020978   IPI01020786   IPI01021928   
Protein Interaction databases
DIP (DOE-UCLA)P07585
IntAct (EBI)P07585
FunCoupENSG00000011465
BioGRIDDCN
IntegromeDBDCN
STRING (EMBL)DCN
ZODIACDCN
Ontologies - Pathways
QuickGOP07585
Ontology : AmiGOkidney development  placenta development  protein kinase inhibitor activity  collagen binding  glycosaminoglycan binding  extracellular region  collagen type VI trimer  extracellular space  cytoplasm  Golgi lumen  carbohydrate metabolic process  negative regulation of protein kinase activity  skeletal muscle tissue development  aging  response to mechanical stimulus  organ morphogenesis  positive regulation of autophagy  cytokine-mediated signaling pathway  peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan  extracellular matrix disassembly  extracellular matrix organization  glycosaminoglycan metabolic process  chondroitin sulfate metabolic process  chondroitin sulfate biosynthetic process  chondroitin sulfate catabolic process  dermatan sulfate biosynthetic process  extracellular matrix  extracellular matrix  response to lipopolysaccharide  wound healing  lysosomal lumen  small molecule metabolic process  poly(A) RNA binding  negative regulation of JAK-STAT cascade  protein N-terminus binding  extracellular matrix binding  negative regulation of cyclin-dependent protein kinase activity  
Ontology : EGO-EBIkidney development  placenta development  protein kinase inhibitor activity  collagen binding  glycosaminoglycan binding  extracellular region  collagen type VI trimer  extracellular space  cytoplasm  Golgi lumen  carbohydrate metabolic process  negative regulation of protein kinase activity  skeletal muscle tissue development  aging  response to mechanical stimulus  organ morphogenesis  positive regulation of autophagy  cytokine-mediated signaling pathway  peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan  extracellular matrix disassembly  extracellular matrix organization  glycosaminoglycan metabolic process  chondroitin sulfate metabolic process  chondroitin sulfate biosynthetic process  chondroitin sulfate catabolic process  dermatan sulfate biosynthetic process  extracellular matrix  extracellular matrix  response to lipopolysaccharide  wound healing  lysosomal lumen  small molecule metabolic process  poly(A) RNA binding  negative regulation of JAK-STAT cascade  protein N-terminus binding  extracellular matrix binding  negative regulation of cyclin-dependent protein kinase activity  
Pathways : BIOCARTASmall Leucine-rich Proteoglycan (SLRP) molecules [Genes]   
Pathways : KEGGTGF-beta signaling pathway    Proteoglycans in cancer   
Protein Interaction DatabaseDCN
Atlas of Cancer Signalling NetworkDCN
Wikipedia pathwaysDCN
Orthology - Evolution
OrthoDB1634
GeneTree (enSembl)ENSG00000011465
Phylogenetic Trees/Animal Genes : TreeFamDCN
Homologs : HomoloGeneDCN
Homology/Alignments : Family Browser (UCSC)DCN
Gene fusions - Rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerDCN [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCN
dbVarDCN
ClinVarDCN
1000_GenomesDCN 
Exome Variant ServerDCN
Exome Aggregation Consortium (ExAC)ENSG00000011465
SNP (GeneSNP Utah)DCN
SNP : HGBaseDCN
Genetic variants : HAPMAPDCN
Genomic Variants (DGV)DCN [DGVbeta]
Mutations
ICGC Data PortalDCN 
TCGA Data PortalDCN 
Tumor PortalDCN
TCGA Copy Number PortalDCN
Somatic Mutations in Cancer : COSMICDCN 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DCN
DgiDB (Drug Gene Interaction Database)DCN
DoCM (Curated mutations)DCN (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCN (select a term)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
Diseases
DECIPHER (Syndromes)12:91539035-91576806
CONAN: Copy Number AnalysisDCN 
Mutations and Diseases : HGMDDCN
OMIM125255    610048   
MedgenDCN
NextProtP07585 [Medical]
TSGene1634
GENETestsDCN
Huge Navigator DCN [HugePedia]  DCN [HugeCancerGEM]
snp3D : Map Gene to Disease1634
BioCentury BCIQDCN
General knowledge
Chemical/Protein Interactions : CTD1634
Chemical/Pharm GKB GenePA27177
Clinical trialDCN
Other databases
Probes
Litterature
PubMed190 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCN
GoPubMedDCN
iHOPDCN
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Jan 16 18:27:17 CET 2016

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