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DCP1B (decapping mRNA 1B)

Identity

Alias_namesDCP1 decapping enzyme homolog B (S. cerevisiae)
Alias_symbol (synonym)FLJ31638
Other aliasDCP1
HGNC (Hugo) DCP1B
LocusID (NCBI) 196513
Atlas_Id 62332
Location 12p13.33  [Link to chromosome band 12p13]
Location_base_pair Starts at 1946048 and ends at 2004535 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADIPOR2 (12p13.33) / DCP1B (12p13.33)PPP5C (19q13.32) / DCP1B (12p13.33)SCNN1A (12p13.31) / DCP1B (12p13.33)
ADIPOR2 DCP1BSCNN1A DCP1B

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 2 ]
  ADIPOR2/DCP1B (12p13)
SCNN1A/DCP1B (12p13)

External links

Nomenclature
HGNC (Hugo)DCP1B   24451
Cards
Entrez_Gene (NCBI)DCP1B  196513  decapping mRNA 1B
AliasesDCP1
GeneCards (Weizmann)DCP1B
Ensembl hg19 (Hinxton)ENSG00000151065 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000151065 [Gene_View]  ENSG00000151065 [Sequence]  chr12:1946048-2004535 [Contig_View]  DCP1B [Vega]
ICGC DataPortalENSG00000151065
TCGA cBioPortalDCP1B
AceView (NCBI)DCP1B
Genatlas (Paris)DCP1B
WikiGenes196513
SOURCE (Princeton)DCP1B
Genetics Home Reference (NIH)DCP1B
Genomic and cartography
GoldenPath hg38 (UCSC)DCP1B  -     chr12:1946048-2004535 -  12p13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCP1B  -     12p13.33   [Description]    (hg19-Feb_2009)
GoldenPathDCP1B - 12p13.33 [CytoView hg19]  DCP1B - 12p13.33 [CytoView hg38]
ImmunoBaseENSG00000151065
Mapping of homologs : NCBIDCP1B [Mapview hg19]  DCP1B [Mapview hg38]
OMIM609843   
Gene and transcription
Genbank (Entrez)AK056200 AK299203 AK301109 AK310475 AW204088
RefSeq transcript (Entrez)NM_001319292 NM_152640
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DCP1B
Alternative Splicing GalleryENSG00000151065
Gene ExpressionDCP1B [ NCBI-GEO ]   DCP1B [ EBI - ARRAY_EXPRESS ]   DCP1B [ SEEK ]   DCP1B [ MEM ]
Gene Expression Viewer (FireBrowse)DCP1B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)196513
GTEX Portal (Tissue expression)DCP1B
Human Protein AtlasENSG00000151065-DCP1B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IZD4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IZD4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IZD4
Splice isoforms : SwissVarQ8IZD4
PhosPhoSitePlusQ8IZD4
Domains : Interpro (EBI)Dcp1    mRNA_decap_C    PH-like_dom_sf   
Domain families : Pfam (Sanger)DCP1 (PF06058)    mRNA_decap_C (PF16741)   
Domain families : Pfam (NCBI)pfam06058    pfam16741   
Conserved Domain (NCBI)DCP1B
DMDM Disease mutations196513
Blocks (Seattle)DCP1B
SuperfamilyQ8IZD4
Human Protein Atlas [tissue]ENSG00000151065-DCP1B [tissue]
Peptide AtlasQ8IZD4
IPIIPI00328309   IPI00973540   IPI01014855   IPI01016052   IPI00910493   
Protein Interaction databases
DIP (DOE-UCLA)Q8IZD4
IntAct (EBI)Q8IZD4
FunCoupENSG00000151065
BioGRIDDCP1B
STRING (EMBL)DCP1B
ZODIACDCP1B
Ontologies - Pathways
QuickGOQ8IZD4
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  deadenylation-dependent decapping of nuclear-transcribed mRNA  P-body  protein binding  nucleus  cytosol  cytosol  enzyme activator activity  membrane  hydrolase activity  deadenylation-independent decapping of nuclear-transcribed mRNA  positive regulation of catalytic activity  intracellular membrane-bounded organelle  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  deadenylation-dependent decapping of nuclear-transcribed mRNA  P-body  protein binding  nucleus  cytosol  cytosol  enzyme activator activity  membrane  hydrolase activity  deadenylation-independent decapping of nuclear-transcribed mRNA  positive regulation of catalytic activity  intracellular membrane-bounded organelle  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  
NDEx NetworkDCP1B
Atlas of Cancer Signalling NetworkDCP1B
Wikipedia pathwaysDCP1B
Orthology - Evolution
OrthoDB196513
GeneTree (enSembl)ENSG00000151065
Phylogenetic Trees/Animal Genes : TreeFamDCP1B
HOGENOMQ8IZD4
Homologs : HomoloGeneDCP1B
Homology/Alignments : Family Browser (UCSC)DCP1B
Gene fusions - Rearrangements
Fusion PortalADIPOR2 DCP1B
Fusion PortalSCNN1A DCP1B
Fusion : QuiverDCP1B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCP1B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCP1B
dbVarDCP1B
ClinVarDCP1B
1000_GenomesDCP1B 
Exome Variant ServerDCP1B
ExAC (Exome Aggregation Consortium)ENSG00000151065
GNOMAD BrowserENSG00000151065
Varsome BrowserDCP1B
Genetic variants : HAPMAP196513
Genomic Variants (DGV)DCP1B [DGVbeta]
DECIPHERDCP1B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCP1B 
Mutations
ICGC Data PortalDCP1B 
TCGA Data PortalDCP1B 
Broad Tumor PortalDCP1B
OASIS PortalDCP1B [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCP1B  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDCP1B
Mutations and Diseases : HGMDDCP1B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DCP1B
DgiDB (Drug Gene Interaction Database)DCP1B
DoCM (Curated mutations)DCP1B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCP1B (select a term)
intoGenDCP1B
Cancer3DDCP1B(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609843   
Orphanet
DisGeNETDCP1B
MedgenDCP1B
Genetic Testing Registry DCP1B
NextProtQ8IZD4 [Medical]
TSGene196513
GENETestsDCP1B
Target ValidationDCP1B
Huge Navigator DCP1B [HugePedia]
snp3D : Map Gene to Disease196513
BioCentury BCIQDCP1B
ClinGenDCP1B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD196513
Chemical/Pharm GKB GenePA134889143
Clinical trialDCP1B
Miscellaneous
canSAR (ICR)DCP1B (select the gene name)
HarmonizomeDCP1B
DataMed IndexDCP1B
Probes
Litterature
PubMed39 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCP1B
EVEXDCP1B
GoPubMedDCP1B
iHOPDCP1B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun May 10 11:29:11 CEST 2020
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