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DCP2 (decapping mRNA 2)

Identity

Alias_namesDCP2 decapping enzyme homolog (S. cerevisiae)
Alias_symbol (synonym)NUDT20
Other alias
HGNC (Hugo) DCP2
LocusID (NCBI) 167227
Atlas_Id 62333
Location 5q22.2  [Link to chromosome band 5q22]
Location_base_pair Starts at 112312407 and ends at 112357892 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DCP2 (5q22.2) / DCP2 (5q22.2)DCP2 (5q22.2) / NDUFB2 (7q34)DCP2 (5q22.2) / REEP5 (5q22.2)
KLF11 (2p25.1) / DCP2 (5q22.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DCP2   24452
Cards
Entrez_Gene (NCBI)DCP2  167227  decapping mRNA 2
AliasesNUDT20
GeneCards (Weizmann)DCP2
Ensembl hg19 (Hinxton)ENSG00000172795 [Gene_View]  chr5:112312407-112357892 [Contig_View]  DCP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000172795 [Gene_View]  chr5:112312407-112357892 [Contig_View]  DCP2 [Vega]
ICGC DataPortalENSG00000172795
TCGA cBioPortalDCP2
AceView (NCBI)DCP2
Genatlas (Paris)DCP2
WikiGenes167227
SOURCE (Princeton)DCP2
Genetics Home Reference (NIH)DCP2
Genomic and cartography
GoldenPath hg19 (UCSC)DCP2  -     chr5:112312407-112357892 +  5q22.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DCP2  -     5q22.2   [Description]    (hg38-Dec_2013)
EnsemblDCP2 - 5q22.2 [CytoView hg19]  DCP2 - 5q22.2 [CytoView hg38]
Mapping of homologs : NCBIDCP2 [Mapview hg19]  DCP2 [Mapview hg38]
OMIM609844   
Gene and transcription
Genbank (Entrez)AA837315 AB002445 AK025019 AK090564 AK296361
RefSeq transcript (Entrez)NM_001242377 NM_152624
RefSeq genomic (Entrez)NC_000005 NC_018916 NG_029929 NT_034772 NW_004929323
Consensus coding sequences : CCDS (NCBI)DCP2
Cluster EST : UnigeneHs.443875 [ NCBI ]
CGAP (NCI)Hs.443875
Alternative Splicing GalleryENSG00000172795
Gene ExpressionDCP2 [ NCBI-GEO ]   DCP2 [ EBI - ARRAY_EXPRESS ]   DCP2 [ SEEK ]   DCP2 [ MEM ]
Gene Expression Viewer (FireBrowse)DCP2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)167227
GTEX Portal (Tissue expression)DCP2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IU60   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IU60  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IU60
Splice isoforms : SwissVarQ8IU60
Catalytic activity : Enzyme3.6.1.62 [ Enzyme-Expasy ]   3.6.1.623.6.1.62 [ IntEnz-EBI ]   3.6.1.62 [ BRENDA ]   3.6.1.62 [ KEGG ]   
PhosPhoSitePlusQ8IU60
Domaine pattern : Prosite (Expaxy)NUDIX (PS51462)    NUDIX_BOX (PS00893)   
Domains : Interpro (EBI)mRNA_decapping_BoxA    NUDIX_hydrolase_CS    NUDIX_hydrolase_dom    NUDIX_hydrolase_dom-like   
Domain families : Pfam (Sanger)DCP2 (PF05026)    NUDIX (PF00293)   
Domain families : Pfam (NCBI)pfam05026    pfam00293   
Conserved Domain (NCBI)DCP2
DMDM Disease mutations167227
Blocks (Seattle)DCP2
SuperfamilyQ8IU60
Human Protein AtlasENSG00000172795
Peptide AtlasQ8IU60
HPRD13125
IPIIPI00292382   IPI00440151   IPI00964870   IPI00965018   
Protein Interaction databases
DIP (DOE-UCLA)Q8IU60
IntAct (EBI)Q8IU60
FunCoupENSG00000172795
BioGRIDDCP2
STRING (EMBL)DCP2
ZODIACDCP2
Ontologies - Pathways
QuickGOQ8IU60
Ontology : AmiGOnuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  cytoplasmic mRNA processing body  RNA binding  protein binding  nucleoplasm  cytosol  mRNA catabolic process  gene expression  RISC complex  exoribonuclease activity, producing 5'-phosphomonoesters  cell junction  manganese ion binding  intracellular membrane-bounded organelle  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  m7G(5')pppN diphosphatase activity  histone mRNA catabolic process  RNA phosphodiester bond hydrolysis, exonucleolytic  
Ontology : EGO-EBInuclear-transcribed mRNA catabolic process, nonsense-mediated decay  nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay  cytoplasmic mRNA processing body  RNA binding  protein binding  nucleoplasm  cytosol  mRNA catabolic process  gene expression  RISC complex  exoribonuclease activity, producing 5'-phosphomonoesters  cell junction  manganese ion binding  intracellular membrane-bounded organelle  exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay  m7G(5')pppN diphosphatase activity  histone mRNA catabolic process  RNA phosphodiester bond hydrolysis, exonucleolytic  
Pathways : KEGGRNA degradation   
NDEx NetworkDCP2
Atlas of Cancer Signalling NetworkDCP2
Wikipedia pathwaysDCP2
Orthology - Evolution
OrthoDB167227
GeneTree (enSembl)ENSG00000172795
Phylogenetic Trees/Animal Genes : TreeFamDCP2
HOVERGENQ8IU60
HOGENOMQ8IU60
Homologs : HomoloGeneDCP2
Homology/Alignments : Family Browser (UCSC)DCP2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCP2
dbVarDCP2
ClinVarDCP2
1000_GenomesDCP2 
Exome Variant ServerDCP2
ExAC (Exome Aggregation Consortium)DCP2 (select the gene name)
Genetic variants : HAPMAP167227
Genomic Variants (DGV)DCP2 [DGVbeta]
DECIPHER (Syndromes)5:112312407-112357892  ENSG00000172795
CONAN: Copy Number AnalysisDCP2 
Mutations
ICGC Data PortalDCP2 
TCGA Data PortalDCP2 
Broad Tumor PortalDCP2
OASIS PortalDCP2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCP2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDCP2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DCP2
DgiDB (Drug Gene Interaction Database)DCP2
DoCM (Curated mutations)DCP2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCP2 (select a term)
intoGenDCP2
Cancer3DDCP2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609844   
Orphanet
MedgenDCP2
Genetic Testing Registry DCP2
NextProtQ8IU60 [Medical]
TSGene167227
GENETestsDCP2
Huge Navigator DCP2 [HugePedia]
snp3D : Map Gene to Disease167227
BioCentury BCIQDCP2
ClinGenDCP2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD167227
Chemical/Pharm GKB GenePA134898646
Clinical trialDCP2
Miscellaneous
canSAR (ICR)DCP2 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCP2
EVEXDCP2
GoPubMedDCP2
iHOPDCP2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:01:08 CET 2017

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