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DCTN3 (dynactin subunit 3)

Identity

Alias_namesdynactin 3 (p22)
Alias_symbol (synonym)DCTN-22
Other aliasDCTN22
HGNC (Hugo) DCTN3
LocusID (NCBI) 11258
Atlas_Id 62337
Location 9p13.3  [Link to chromosome band 9p13]
Location_base_pair Starts at 34613545 and ends at 34620523 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ARID3C (9p13.3) / DCTN3 (9p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DCTN3   2713
Cards
Entrez_Gene (NCBI)DCTN3  11258  dynactin subunit 3
AliasesDCTN-22; DCTN22
GeneCards (Weizmann)DCTN3
Ensembl hg19 (Hinxton)ENSG00000137100 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137100 [Gene_View]  chr9:34613545-34620523 [Contig_View]  DCTN3 [Vega]
ICGC DataPortalENSG00000137100
TCGA cBioPortalDCTN3
AceView (NCBI)DCTN3
Genatlas (Paris)DCTN3
WikiGenes11258
SOURCE (Princeton)DCTN3
Genetics Home Reference (NIH)DCTN3
Genomic and cartography
GoldenPath hg38 (UCSC)DCTN3  -     chr9:34613545-34620523 -  9p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCTN3  -     9p13.3   [Description]    (hg19-Feb_2009)
EnsemblDCTN3 - 9p13.3 [CytoView hg19]  DCTN3 - 9p13.3 [CytoView hg38]
Mapping of homologs : NCBIDCTN3 [Mapview hg19]  DCTN3 [Mapview hg38]
OMIM607387   
Gene and transcription
Genbank (Entrez)AF082513 AK055199 AK091661 AK314730 AW953496
RefSeq transcript (Entrez)NM_001281425 NM_001281426 NM_001281427 NM_007234 NM_024348
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DCTN3
Cluster EST : UnigeneHs.511768 [ NCBI ]
CGAP (NCI)Hs.511768
Alternative Splicing GalleryENSG00000137100
Gene ExpressionDCTN3 [ NCBI-GEO ]   DCTN3 [ EBI - ARRAY_EXPRESS ]   DCTN3 [ SEEK ]   DCTN3 [ MEM ]
Gene Expression Viewer (FireBrowse)DCTN3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11258
GTEX Portal (Tissue expression)DCTN3
Human Protein AtlasENSG00000137100-DCTN3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75935   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75935  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75935
Splice isoforms : SwissVarO75935
PhosPhoSitePlusO75935
Domains : Interpro (EBI)Dynactin_p22   
Domain families : Pfam (Sanger)Dynactin_p22 (PF07426)   
Domain families : Pfam (NCBI)pfam07426   
Conserved Domain (NCBI)DCTN3
DMDM Disease mutations11258
Blocks (Seattle)DCTN3
SuperfamilyO75935
Human Protein Atlas [tissue]ENSG00000137100-DCTN3 [tissue]
Peptide AtlasO75935
HPRD06303
IPIIPI00027014   IPI00013654   IPI00514971   IPI00385809   IPI00747408   
Protein Interaction databases
DIP (DOE-UCLA)O75935
IntAct (EBI)O75935
FunCoupENSG00000137100
BioGRIDDCTN3
STRING (EMBL)DCTN3
ZODIACDCTN3
Ontologies - Pathways
QuickGOO75935
Ontology : AmiGOG2/M transition of mitotic cell cycle  mitotic cell cycle  condensed chromosome kinetochore  cytokinesis  structural molecule activity  protein binding  nucleolus  centrosome  spindle  cytosol  cytosol  dynactin complex  ER to Golgi vesicle-mediated transport  microtubule-based process  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  cleavage furrow  perinuclear region of cytoplasm  ciliary basal body docking  
Ontology : EGO-EBIG2/M transition of mitotic cell cycle  mitotic cell cycle  condensed chromosome kinetochore  cytokinesis  structural molecule activity  protein binding  nucleolus  centrosome  spindle  cytosol  cytosol  dynactin complex  ER to Golgi vesicle-mediated transport  microtubule-based process  antigen processing and presentation of exogenous peptide antigen via MHC class II  midbody  cleavage furrow  perinuclear region of cytoplasm  ciliary basal body docking  
Pathways : BIOCARTALissencephaly gene (LIS1) in neuronal migration and development [Genes]   
NDEx NetworkDCTN3
Atlas of Cancer Signalling NetworkDCTN3
Wikipedia pathwaysDCTN3
Orthology - Evolution
OrthoDB11258
GeneTree (enSembl)ENSG00000137100
Phylogenetic Trees/Animal Genes : TreeFamDCTN3
HOVERGENO75935
HOGENOMO75935
Homologs : HomoloGeneDCTN3
Homology/Alignments : Family Browser (UCSC)DCTN3
Gene fusions - Rearrangements
Tumor Fusion PortalDCTN3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCTN3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCTN3
dbVarDCTN3
ClinVarDCTN3
1000_GenomesDCTN3 
Exome Variant ServerDCTN3
ExAC (Exome Aggregation Consortium)ENSG00000137100
GNOMAD BrowserENSG00000137100
Genetic variants : HAPMAP11258
Genomic Variants (DGV)DCTN3 [DGVbeta]
DECIPHERDCTN3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCTN3 
Mutations
ICGC Data PortalDCTN3 
TCGA Data PortalDCTN3 
Broad Tumor PortalDCTN3
OASIS PortalDCTN3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCTN3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDCTN3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DCTN3
DgiDB (Drug Gene Interaction Database)DCTN3
DoCM (Curated mutations)DCTN3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCTN3 (select a term)
intoGenDCTN3
Cancer3DDCTN3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607387   
Orphanet
DisGeNETDCTN3
MedgenDCTN3
Genetic Testing Registry DCTN3
NextProtO75935 [Medical]
TSGene11258
GENETestsDCTN3
Target ValidationDCTN3
Huge Navigator DCTN3 [HugePedia]
snp3D : Map Gene to Disease11258
BioCentury BCIQDCTN3
ClinGenDCTN3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11258
Chemical/Pharm GKB GenePA27182
Clinical trialDCTN3
Miscellaneous
canSAR (ICR)DCTN3 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCTN3
EVEXDCTN3
GoPubMedDCTN3
iHOPDCTN3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:19:36 CET 2017

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