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DCTN6 (dynactin subunit 6)

Identity

Alias_namesdynactin 6
Alias_symbol (synonym)WS-3
Other aliasWS3
p27
HGNC (Hugo) DCTN6
LocusID (NCBI) 10671
Atlas_Id 78518
Location 8p12  [Link to chromosome band 8p12]
Location_base_pair Starts at 30156297 and ends at 30183639 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
EXT1 (8q24.11) / DCTN6 (8p12)MEX3D (19p13.3) / DCTN6 (8p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DCTN6   16964
Cards
Entrez_Gene (NCBI)DCTN6  10671  dynactin subunit 6
AliasesWS-3; WS3; p27
GeneCards (Weizmann)DCTN6
Ensembl hg19 (Hinxton)ENSG00000104671 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104671 [Gene_View]  chr8:30156297-30183639 [Contig_View]  DCTN6 [Vega]
ICGC DataPortalENSG00000104671
TCGA cBioPortalDCTN6
AceView (NCBI)DCTN6
Genatlas (Paris)DCTN6
WikiGenes10671
SOURCE (Princeton)DCTN6
Genetics Home Reference (NIH)DCTN6
Genomic and cartography
GoldenPath hg38 (UCSC)DCTN6  -     chr8:30156297-30183639 +  8p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCTN6  -     8p12   [Description]    (hg19-Feb_2009)
EnsemblDCTN6 - 8p12 [CytoView hg19]  DCTN6 - 8p12 [CytoView hg38]
Mapping of homologs : NCBIDCTN6 [Mapview hg19]  DCTN6 [Mapview hg38]
OMIM612963   
Gene and transcription
Genbank (Entrez)AK314128 BC013175 BI562535 CR456851 D79389
RefSeq transcript (Entrez)NM_006571
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DCTN6
Cluster EST : UnigeneHs.721134 [ NCBI ]
CGAP (NCI)Hs.721134
Alternative Splicing GalleryENSG00000104671
Gene ExpressionDCTN6 [ NCBI-GEO ]   DCTN6 [ EBI - ARRAY_EXPRESS ]   DCTN6 [ SEEK ]   DCTN6 [ MEM ]
Gene Expression Viewer (FireBrowse)DCTN6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10671
GTEX Portal (Tissue expression)DCTN6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00399   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00399  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00399
Splice isoforms : SwissVarO00399
PhosPhoSitePlusO00399
Domains : Interpro (EBI)DCTN6    Hexapep    Trimer_LpxA-like   
Domain families : Pfam (Sanger)Hexapep (PF00132)   
Domain families : Pfam (NCBI)pfam00132   
Conserved Domain (NCBI)DCTN6
DMDM Disease mutations10671
Blocks (Seattle)DCTN6
PDB (SRS)3TV0   
PDB (PDBSum)3TV0   
PDB (IMB)3TV0   
PDB (RSDB)3TV0   
Structural Biology KnowledgeBase3TV0   
SCOP (Structural Classification of Proteins)3TV0   
CATH (Classification of proteins structures)3TV0   
SuperfamilyO00399
Human Protein AtlasENSG00000104671
Peptide AtlasO00399
HPRD09907
IPIIPI00220770   IPI00974391   IPI00974505   IPI00974491   IPI00974458   
Protein Interaction databases
DIP (DOE-UCLA)O00399
IntAct (EBI)O00399
FunCoupENSG00000104671
BioGRIDDCTN6
STRING (EMBL)DCTN6
ZODIACDCTN6
Ontologies - Pathways
QuickGOO00399
Ontology : AmiGOcondensed chromosome kinetochore  centrosome  cytosol  dynactin complex  ER to Golgi vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  
Ontology : EGO-EBIcondensed chromosome kinetochore  centrosome  cytosol  dynactin complex  ER to Golgi vesicle-mediated transport  antigen processing and presentation of exogenous peptide antigen via MHC class II  
Pathways : BIOCARTALissencephaly gene (LIS1) in neuronal migration and development [Genes]   
Pathways : KEGGVasopressin-regulated water reabsorption   
NDEx NetworkDCTN6
Atlas of Cancer Signalling NetworkDCTN6
Wikipedia pathwaysDCTN6
Orthology - Evolution
OrthoDB10671
GeneTree (enSembl)ENSG00000104671
Phylogenetic Trees/Animal Genes : TreeFamDCTN6
HOVERGENO00399
HOGENOMO00399
Homologs : HomoloGeneDCTN6
Homology/Alignments : Family Browser (UCSC)DCTN6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCTN6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCTN6
dbVarDCTN6
ClinVarDCTN6
1000_GenomesDCTN6 
Exome Variant ServerDCTN6
ExAC (Exome Aggregation Consortium)DCTN6 (select the gene name)
Genetic variants : HAPMAP10671
Genomic Variants (DGV)DCTN6 [DGVbeta]
DECIPHERDCTN6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCTN6 
Mutations
ICGC Data PortalDCTN6 
TCGA Data PortalDCTN6 
Broad Tumor PortalDCTN6
OASIS PortalDCTN6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCTN6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDCTN6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DCTN6
DgiDB (Drug Gene Interaction Database)DCTN6
DoCM (Curated mutations)DCTN6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DCTN6 (select a term)
intoGenDCTN6
Cancer3DDCTN6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612963   
Orphanet
MedgenDCTN6
Genetic Testing Registry DCTN6
NextProtO00399 [Medical]
TSGene10671
GENETestsDCTN6
Target ValidationDCTN6
Huge Navigator DCTN6 [HugePedia]
snp3D : Map Gene to Disease10671
BioCentury BCIQDCTN6
ClinGenDCTN6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10671
Chemical/Pharm GKB GenePA134927975
Clinical trialDCTN6
Miscellaneous
canSAR (ICR)DCTN6 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDCTN6
EVEXDCTN6
GoPubMedDCTN6
iHOPDCTN6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:05:56 CEST 2017

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