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DCTN6 (dynactin subunit 6)

Identity

Alias (NCBI)WS-3
WS3
p27
HGNC (Hugo) DCTN6
HGNC Alias symbWS-3
HGNC Previous namedynactin 6
LocusID (NCBI) 10671
Atlas_Id 78518
Location 8p12  [Link to chromosome band 8p12]
Location_base_pair Starts at 30156369 and ends at 30183639 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EXT1 (8q24.11)::DCTN6 (8p12)MEX3D (19p13.3)::DCTN6 (8p12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)DCTN6   16964
Cards
Entrez_Gene (NCBI)DCTN6    dynactin subunit 6
AliasesWS-3; WS3; p27
GeneCards (Weizmann)DCTN6
Ensembl hg19 (Hinxton)ENSG00000104671 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104671 [Gene_View]  ENSG00000104671 [Sequence]  chr8:30156369-30183639 [Contig_View]  DCTN6 [Vega]
ICGC DataPortalENSG00000104671
TCGA cBioPortalDCTN6
AceView (NCBI)DCTN6
Genatlas (Paris)DCTN6
SOURCE (Princeton)DCTN6
Genetics Home Reference (NIH)DCTN6
Genomic and cartography
GoldenPath hg38 (UCSC)DCTN6  -     chr8:30156369-30183639 +  8p12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DCTN6  -     8p12   [Description]    (hg19-Feb_2009)
GoldenPathDCTN6 - 8p12 [CytoView hg19]  DCTN6 - 8p12 [CytoView hg38]
ImmunoBaseENSG00000104671
Genome Data Viewer NCBIDCTN6 [Mapview hg19]  
OMIM612963   
Gene and transcription
Genbank (Entrez)AK314128 BC013175 BI562535 CR456851 D79389
RefSeq transcript (Entrez)NM_006571
Consensus coding sequences : CCDS (NCBI)DCTN6
Gene ExpressionDCTN6 [ NCBI-GEO ]   DCTN6 [ EBI - ARRAY_EXPRESS ]   DCTN6 [ SEEK ]   DCTN6 [ MEM ]
Gene Expression Viewer (FireBrowse)DCTN6 [ Firebrowse - Broad ]
GenevisibleExpression of DCTN6 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10671
GTEX Portal (Tissue expression)DCTN6
Human Protein AtlasENSG00000104671-DCTN6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO00399   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO00399  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO00399
PhosPhoSitePlusO00399
Domains : Interpro (EBI)DCTN6    Hexapep    Trimer_LpxA-like_sf   
Domain families : Pfam (Sanger)Hexapep (PF00132)   
Domain families : Pfam (NCBI)pfam00132   
Conserved Domain (NCBI)DCTN6
PDB (RSDB)3TV0   
PDB Europe3TV0   
PDB (PDBSum)3TV0   
PDB (IMB)3TV0   
Structural Biology KnowledgeBase3TV0   
SCOP (Structural Classification of Proteins)3TV0   
CATH (Classification of proteins structures)3TV0   
SuperfamilyO00399
AlphaFold pdb e-kbO00399   
Human Protein Atlas [tissue]ENSG00000104671-DCTN6 [tissue]
HPRD09907
Protein Interaction databases
DIP (DOE-UCLA)O00399
IntAct (EBI)O00399
BioGRIDDCTN6
STRING (EMBL)DCTN6
ZODIACDCTN6
Ontologies - Pathways
QuickGOO00399
Ontology : AmiGOkinetochore  centrosome  cytosol  dynactin complex  endoplasmic reticulum to Golgi vesicle-mediated transport  mitotic spindle organization  antigen processing and presentation of exogenous peptide antigen via MHC class II  dynein complex binding  
Ontology : EGO-EBIkinetochore  centrosome  cytosol  dynactin complex  endoplasmic reticulum to Golgi vesicle-mediated transport  mitotic spindle organization  antigen processing and presentation of exogenous peptide antigen via MHC class II  dynein complex binding  
Pathways : BIOCARTALissencephaly gene (LIS1) in neuronal migration and development [Genes]   
NDEx NetworkDCTN6
Atlas of Cancer Signalling NetworkDCTN6
Wikipedia pathwaysDCTN6
Orthology - Evolution
OrthoDB10671
GeneTree (enSembl)ENSG00000104671
Phylogenetic Trees/Animal Genes : TreeFamDCTN6
Homologs : HomoloGeneDCTN6
Homology/Alignments : Family Browser (UCSC)DCTN6
Gene fusions - Rearrangements
Fusion : QuiverDCTN6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDCTN6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DCTN6
dbVarDCTN6
ClinVarDCTN6
MonarchDCTN6
1000_GenomesDCTN6 
Exome Variant ServerDCTN6
GNOMAD BrowserENSG00000104671
Varsome BrowserDCTN6
ACMGDCTN6 variants
VarityO00399
Genomic Variants (DGV)DCTN6 [DGVbeta]
DECIPHERDCTN6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDCTN6 
Mutations
ICGC Data PortalDCTN6 
TCGA Data PortalDCTN6 
Broad Tumor PortalDCTN6
OASIS PortalDCTN6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDCTN6  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDCTN6
Mutations and Diseases : HGMDDCTN6
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaDCTN6
DgiDB (Drug Gene Interaction Database)DCTN6
DoCM (Curated mutations)DCTN6
CIViC (Clinical Interpretations of Variants in Cancer)DCTN6
Cancer3DDCTN6
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612963   
Orphanet
DisGeNETDCTN6
MedgenDCTN6
Genetic Testing Registry DCTN6
NextProtO00399 [Medical]
GENETestsDCTN6
Target ValidationDCTN6
Huge Navigator DCTN6 [HugePedia]
ClinGenDCTN6
Clinical trials, drugs, therapy
MyCancerGenomeDCTN6
Protein Interactions : CTDDCTN6
Pharm GKB GenePA134927975
PharosO00399
Clinical trialDCTN6
Miscellaneous
canSAR (ICR)DCTN6
HarmonizomeDCTN6
ARCHS4DCTN6
DataMed IndexDCTN6
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXDCTN6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sun Jan 16 18:50:13 CET 2022

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