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DCXR (dicarbonyl/L-xylulose reductase)

Identity

Other namesDCR
HCR2
HCRII
KIDCR
P34H
SDR20C1
XR
HGNC (Hugo) DCXR
LocusID (NCBI) 51181
Location 17q25.3
Location_base_pair Starts at 79993757 and ends at 79995573 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DCXR   18985
Cards
Entrez_Gene (NCBI)DCXR  51181  dicarbonyl/L-xylulose reductase
GeneCards (Weizmann)DCXR
Ensembl (Hinxton)ENSG00000169738 [Gene_View]  chr17:79993757-79995573 [Contig_View]  DCXR [Vega]
AceView (NCBI)DCXR
Genatlas (Paris)DCXR
WikiGenes51181
SOURCE (Princeton)NM_001195218 NM_016286
Genomic and cartography
GoldenPath (UCSC)DCXR  -  17q25.3   chr17:79993757-79995573 -  17q25.3   [Description]    (hg19-Feb_2009)
EnsemblDCXR - 17q25.3 [CytoView]
Mapping of homologs : NCBIDCXR [Mapview]
OMIM260800   608347   
Gene and transcription
Genbank (Entrez)AA446582 AB013846 AF113123 AF139841 AF515623
RefSeq transcript (Entrez)NM_001195218 NM_016286
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NG_027681 NT_010663 NW_001838459 NW_004929408
Consensus coding sequences : CCDS (NCBI)DCXR
Cluster EST : UnigeneHs.9857 [ NCBI ]
CGAP (NCI)Hs.9857
Alternative Splicing : Fast-db (Paris)GSHG0013839
Alternative Splicing GalleryENSG00000169738
Gene ExpressionDCXR [ NCBI-GEO ]     DCXR [ SEEK ]   DCXR [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z4W1 (Uniprot)
NextProtQ7Z4W1  [Medical]
With graphics : InterProQ7Z4W1
Splice isoforms : SwissVarQ7Z4W1 (Swissvar)
Catalytic activity : Enzyme1.1.1.10 [ Enzyme-Expasy ]   1.1.1.101.1.1.10 [ IntEnz-EBI ]   1.1.1.10 [ BRENDA ]   1.1.1.10 [ KEGG ]   
Domaine pattern : Prosite (Expaxy)ADH_SHORT (PS00061)   
Domains : Interpro (EBI)DH_sc/Rdtase_SDR    Glc/ribitol_DH    NAD(P)-bd_dom    Sc_DH/Rdtase_CS   
Related proteins : CluSTrQ7Z4W1
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
DMDM Disease mutations51181
Blocks (Seattle)Q7Z4W1
PDB (SRS)1PR9    1WNT    3D3W   
PDB (PDBSum)1PR9    1WNT    3D3W   
PDB (IMB)1PR9    1WNT    3D3W   
PDB (RSDB)1PR9    1WNT    3D3W   
Human Protein AtlasENSG00000169738
Peptide AtlasQ7Z4W1
HPRD16320
IPIIPI00448095   IPI00797249   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z4W1
IntAct (EBI)Q7Z4W1
FunCoupENSG00000169738
BioGRIDDCXR
InParanoidQ7Z4W1
Interologous Interaction database Q7Z4W1
IntegromeDBDCXR
STRING (EMBL)DCXR
Ontologies - Pathways
Ontology : AmiGOcytoplasmic microtubule  microvillus  brush border  xylulose metabolic process  glucose metabolic process  NADP metabolic process  membrane  oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor  D-xylose metabolic process  L-xylulose reductase (NADP+) activity  protein homotetramerization  oxidation-reduction process  
Ontology : EGO-EBIcytoplasmic microtubule  microvillus  brush border  xylulose metabolic process  glucose metabolic process  NADP metabolic process  membrane  oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor  D-xylose metabolic process  L-xylulose reductase (NADP+) activity  protein homotetramerization  oxidation-reduction process  
Pathways : KEGGPentose and glucuronate interconversions   
REACTOMEDCXR
Protein Interaction DatabaseDCXR
Wikipedia pathwaysDCXR
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DCXR
SNP (GeneSNP Utah)DCXR
SNP : HGBaseDCXR
Genetic variants : HAPMAPDCXR
1000_GenomesDCXR 
ICGC programENSG00000169738 
Somatic Mutations in Cancer : COSMICDCXR 
CONAN: Copy Number AnalysisDCXR 
Mutations and Diseases : HGMDDCXR
OMIM260800    608347   
GENETestsDCXR
Disease Genetic AssociationDCXR
Huge Navigator DCXR [HugePedia]  DCXR [HugeCancerGEM]
Genomic VariantsDCXR  DCXR [DGVbeta]
Exome VariantDCXR
dbVarDCXR
ClinVarDCXR
snp3D : Map Gene to Disease51181
General knowledge
Homologs : HomoloGeneDCXR
Homology/Alignments : Family Browser (UCSC)DCXR
Phylogenetic Trees/Animal Genes : TreeFamDCXR
Chemical/Protein Interactions : CTD51181
Chemical/Pharm GKB GenePA38772
Clinical trialDCXR
Cancer Resource (Charite)ENSG00000169738
Other databases
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
CoreMineDCXR
iHOPDCXR
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Apr 18 16:52:32 CEST 2014

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