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DDI2 (DNA damage inducible 1 homolog 2)

Identity

Alias_namesDDI1, DNA-damage inducible 1, homolog 2 (S. cerevisiae)
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
DNA-damage inducible 1 homolog 2
Alias_symbol (synonym)MGC14844
Other alias-
HGNC (Hugo) DDI2
LocusID (NCBI) 84301
Atlas_Id 54251
Location 1p36.21  [Link to chromosome band 1p36]
Location_base_pair Starts at 15943953 and ends at 15987552 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DDI2 (1p36.21) / EFHD2 (1p36.21)DDI2 (1p36.21) / MTOR (1p36.22)NCK2 (2q12.2) / DDI2 (1p36.21)
DDI2 1p36.21 / MTOR 1p36.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDI2   24578
Cards
Entrez_Gene (NCBI)DDI2  84301  DNA damage inducible 1 homolog 2
Aliases
GeneCards (Weizmann)DDI2
Ensembl hg19 (Hinxton)ENSG00000197312 [Gene_View]  chr1:15943953-15987552 [Contig_View]  DDI2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197312 [Gene_View]  chr1:15943953-15987552 [Contig_View]  DDI2 [Vega]
ICGC DataPortalENSG00000197312
TCGA cBioPortalDDI2
AceView (NCBI)DDI2
Genatlas (Paris)DDI2
WikiGenes84301
SOURCE (Princeton)DDI2
Genetics Home Reference (NIH)DDI2
Genomic and cartography
GoldenPath hg19 (UCSC)DDI2  -     chr1:15943953-15987552 +  1p36.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DDI2  -     1p36.21   [Description]    (hg38-Dec_2013)
EnsemblDDI2 - 1p36.21 [CytoView hg19]  DDI2 - 1p36.21 [CytoView hg38]
Mapping of homologs : NCBIDDI2 [Mapview hg19]  DDI2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK057374 AK293006 AL598343 BC006011 BN000122
RefSeq transcript (Entrez)NM_032341
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929289
Consensus coding sequences : CCDS (NCBI)DDI2
Cluster EST : UnigeneHs.718857 [ NCBI ]
CGAP (NCI)Hs.718857
Alternative Splicing GalleryENSG00000197312
Gene ExpressionDDI2 [ NCBI-GEO ]   DDI2 [ EBI - ARRAY_EXPRESS ]   DDI2 [ SEEK ]   DDI2 [ MEM ]
Gene Expression Viewer (FireBrowse)DDI2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)84301
GTEX Portal (Tissue expression)DDI2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TDH0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TDH0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TDH0
Splice isoforms : SwissVarQ5TDH0
PhosPhoSitePlusQ5TDH0
Domaine pattern : Prosite (Expaxy)UBIQUITIN_2 (PS50053)   
Domains : Interpro (EBI)Peptidase_aspartic_DDI1-type    Peptidase_aspartic_dom    Ubiquitin-rel_dom    Ubiquitin_dom   
Domain families : Pfam (Sanger)Asp_protease (PF09668)    ubiquitin (PF00240)   
Domain families : Pfam (NCBI)pfam09668    pfam00240   
Conserved Domain (NCBI)DDI2
DMDM Disease mutations84301
Blocks (Seattle)DDI2
SuperfamilyQ5TDH0
Human Protein AtlasENSG00000197312
Peptide AtlasQ5TDH0
HPRD18702
IPIIPI00845258   IPI00796836   IPI00031618   IPI01022745   IPI00871310   
Protein Interaction databases
DIP (DOE-UCLA)Q5TDH0
IntAct (EBI)Q5TDH0
FunCoupENSG00000197312
BioGRIDDDI2
STRING (EMBL)DDI2
ZODIACDDI2
Ontologies - Pathways
QuickGOQ5TDH0
Ontology : AmiGOaspartic-type endopeptidase activity  nucleoplasm  cytoplasm  proteolysis  
Ontology : EGO-EBIaspartic-type endopeptidase activity  nucleoplasm  cytoplasm  proteolysis  
NDEx NetworkDDI2
Atlas of Cancer Signalling NetworkDDI2
Wikipedia pathwaysDDI2
Orthology - Evolution
OrthoDB84301
GeneTree (enSembl)ENSG00000197312
Phylogenetic Trees/Animal Genes : TreeFamDDI2
HOVERGENQ5TDH0
HOGENOMQ5TDH0
Homologs : HomoloGeneDDI2
Homology/Alignments : Family Browser (UCSC)DDI2
Gene fusions - Rearrangements
Fusion : MitelmanDDI2/EFHD2 [1p36.21/1p36.21]  
Fusion : MitelmanDDI2/MTOR [1p36.21/1p36.22]  [t(1;1)(p36;p36)]  
Fusion: TCGADDI2 1p36.21 MTOR 1p36.22 LUAD
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDI2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDI2
dbVarDDI2
ClinVarDDI2
1000_GenomesDDI2 
Exome Variant ServerDDI2
ExAC (Exome Aggregation Consortium)DDI2 (select the gene name)
Genetic variants : HAPMAP84301
Genomic Variants (DGV)DDI2 [DGVbeta]
DECIPHER (Syndromes)1:15943953-15987552  ENSG00000197312
CONAN: Copy Number AnalysisDDI2 
Mutations
ICGC Data PortalDDI2 
TCGA Data PortalDDI2 
Broad Tumor PortalDDI2
OASIS PortalDDI2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDI2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDI2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDI2
DgiDB (Drug Gene Interaction Database)DDI2
DoCM (Curated mutations)DDI2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDI2 (select a term)
intoGenDDI2
Cancer3DDDI2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDDI2
Genetic Testing Registry DDI2
NextProtQ5TDH0 [Medical]
TSGene84301
GENETestsDDI2
Huge Navigator DDI2 [HugePedia]
snp3D : Map Gene to Disease84301
BioCentury BCIQDDI2
ClinGenDDI2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD84301
Chemical/Pharm GKB GenePA142672004
Clinical trialDDI2
Miscellaneous
canSAR (ICR)DDI2 (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDI2
EVEXDDI2
GoPubMedDDI2
iHOPDDI2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:58:33 CEST 2017

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