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DDIT4L (DNA damage inducible transcript 4 like)

Identity

Alias (NCBI)REDD2
Rtp801L
HGNC (Hugo) DDIT4L
HGNC Alias symbREDD2
Rtp801L
HGNC Alias nameregulated in development and DNA damage response 2
  similar to Smhs1 protein
HGNC Previous nameDNA-damage-inducible transcript 4-like
LocusID (NCBI) 115265
Atlas_Id 62351
Location 4q24  [Link to chromosome band 4q24]
Location_base_pair Starts at 100185870 and ends at 100190498 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DDIT4L   30555
Cards
Entrez_Gene (NCBI)DDIT4L    DNA damage inducible transcript 4 like
AliasesREDD2; Rtp801L
GeneCards (Weizmann)DDIT4L
Ensembl hg19 (Hinxton)ENSG00000145358 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000145358 [Gene_View]  ENSG00000145358 [Sequence]  chr4:100185870-100190498 [Contig_View]  DDIT4L [Vega]
ICGC DataPortalENSG00000145358
TCGA cBioPortalDDIT4L
AceView (NCBI)DDIT4L
Genatlas (Paris)DDIT4L
SOURCE (Princeton)DDIT4L
Genetics Home Reference (NIH)DDIT4L
Genomic and cartography
GoldenPath hg38 (UCSC)DDIT4L  -     chr4:100185870-100190498 -  4q24   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDIT4L  -     4q24   [Description]    (hg19-Feb_2009)
GoldenPathDDIT4L - 4q24 [CytoView hg19]  DDIT4L - 4q24 [CytoView hg38]
ImmunoBaseENSG00000145358
genome Data Viewer NCBIDDIT4L [Mapview hg19]  
OMIM607730   
Gene and transcription
Genbank (Entrez)AK094236 AK312926 AL832277 BC013592 DB208869
RefSeq transcript (Entrez)NM_145244
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDIT4L
Alternative Splicing GalleryENSG00000145358
Gene ExpressionDDIT4L [ NCBI-GEO ]   DDIT4L [ EBI - ARRAY_EXPRESS ]   DDIT4L [ SEEK ]   DDIT4L [ MEM ]
Gene Expression Viewer (FireBrowse)DDIT4L [ Firebrowse - Broad ]
GenevisibleExpression of DDIT4L in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115265
GTEX Portal (Tissue expression)DDIT4L
Human Protein AtlasENSG00000145358-DDIT4L [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96D03   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96D03  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96D03
Splice isoforms : SwissVarQ96D03
PhosPhoSitePlusQ96D03
Domains : Interpro (EBI)RTP801-like    RTP801-like_C_sf   
Domain families : Pfam (Sanger)RTP801_C (PF07809)   
Domain families : Pfam (NCBI)pfam07809   
Conserved Domain (NCBI)DDIT4L
Blocks (Seattle)DDIT4L
SuperfamilyQ96D03
Human Protein Atlas [tissue]ENSG00000145358-DDIT4L [tissue]
Peptide AtlasQ96D03
HPRD09663
IPIIPI00060544   IPI00966283   IPI00965462   
Protein Interaction databases
DIP (DOE-UCLA)Q96D03
IntAct (EBI)Q96D03
BioGRIDDDIT4L
STRING (EMBL)DDIT4L
ZODIACDDIT4L
Ontologies - Pathways
QuickGOQ96D03
Ontology : AmiGOprotein binding  cytoplasm  negative regulation of signal transduction  
Ontology : EGO-EBIprotein binding  cytoplasm  negative regulation of signal transduction  
NDEx NetworkDDIT4L
Atlas of Cancer Signalling NetworkDDIT4L
Wikipedia pathwaysDDIT4L
Orthology - Evolution
OrthoDB115265
GeneTree (enSembl)ENSG00000145358
Phylogenetic Trees/Animal Genes : TreeFamDDIT4L
HOGENOMQ96D03
Homologs : HomoloGeneDDIT4L
Homology/Alignments : Family Browser (UCSC)DDIT4L
Gene fusions - Rearrangements
Fusion : QuiverDDIT4L
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDIT4L [hg38]
dbVarDDIT4L
ClinVarDDIT4L
MonarchDDIT4L
1000_GenomesDDIT4L 
Exome Variant ServerDDIT4L
GNOMAD BrowserENSG00000145358
Varsome BrowserDDIT4L
Genomic Variants (DGV)DDIT4L [DGVbeta]
DECIPHERDDIT4L [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDIT4L 
Mutations
ICGC Data PortalDDIT4L 
TCGA Data PortalDDIT4L 
Broad Tumor PortalDDIT4L
OASIS PortalDDIT4L [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDIT4L  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DDDIT4L
Mutations and Diseases : HGMDDDIT4L
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDIT4L
DgiDB (Drug Gene Interaction Database)DDIT4L
DoCM (Curated mutations)DDIT4L (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDIT4L (select a term)
intoGenDDIT4L
Cancer3DDDIT4L(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607730   
Orphanet
DisGeNETDDIT4L
MedgenDDIT4L
Genetic Testing Registry DDIT4L
NextProtQ96D03 [Medical]
GENETestsDDIT4L
Target ValidationDDIT4L
Huge Navigator DDIT4L [HugePedia]
ClinGenDDIT4L
Clinical trials, drugs, therapy
MyCancerGenomeDDIT4L
Protein Interactions : CTD
Pharm GKB GenePA128394749
Clinical trialDDIT4L
Miscellaneous
canSAR (ICR)DDIT4L (select the gene name)
HarmonizomeDDIT4L
DataMed IndexDDIT4L
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDIT4L
EVEXDDIT4L
GoPubMedDDIT4L
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 16:51:27 CET 2020
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