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DDOST (dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit)

Identity

Alias_namesdolichyl-diphosphooligosaccharide-protein glycosyltransferase
Alias_symbol (synonym)OST
KIAA0115
OST48
WBP1
Other aliasAGER1
CDG1R
GATD6
OKSWcl45
HGNC (Hugo) DDOST
LocusID (NCBI) 1650
Atlas_Id 40279
Location 1p36.12  [Link to chromosome band 1p36]
Location_base_pair Starts at 20651767 and ends at 20661544 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DDOST (1p36.12) / ITPKC (19q13.2)LYZ (12q15) / DDOST (1p36.12)OSTC (4q25) / DDOST (1p36.12)
SOX6 (11p15.2) / DDOST (1p36.12)TMEM56 (1p21.3) / DDOST (1p36.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDOST   2728
Cards
Entrez_Gene (NCBI)DDOST  1650  dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
AliasesAGER1; CDG1R; GATD6; OKSWcl45; 
OST; OST48; WBP1
GeneCards (Weizmann)DDOST
Ensembl hg19 (Hinxton)ENSG00000244038 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000244038 [Gene_View]  chr1:20651767-20661544 [Contig_View]  DDOST [Vega]
ICGC DataPortalENSG00000244038
TCGA cBioPortalDDOST
AceView (NCBI)DDOST
Genatlas (Paris)DDOST
WikiGenes1650
SOURCE (Princeton)DDOST
Genetics Home Reference (NIH)DDOST
Genomic and cartography
GoldenPath hg38 (UCSC)DDOST  -     chr1:20651767-20661544 -  1p36.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDOST  -     1p36.12   [Description]    (hg19-Feb_2009)
EnsemblDDOST - 1p36.12 [CytoView hg19]  DDOST - 1p36.12 [CytoView hg38]
Mapping of homologs : NCBIDDOST [Mapview hg19]  DDOST [Mapview hg38]
OMIM602202   614507   
Gene and transcription
Genbank (Entrez)AB062391 AK296041 AK297009 AK315633 BC002594
RefSeq transcript (Entrez)NM_005216
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDOST
Cluster EST : UnigeneHs.523145 [ NCBI ]
CGAP (NCI)Hs.523145
Alternative Splicing GalleryENSG00000244038
Gene ExpressionDDOST [ NCBI-GEO ]   DDOST [ EBI - ARRAY_EXPRESS ]   DDOST [ SEEK ]   DDOST [ MEM ]
Gene Expression Viewer (FireBrowse)DDOST [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1650
GTEX Portal (Tissue expression)DDOST
Protein : pattern, domain, 3D structure
UniProt/SwissProtP39656   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP39656  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP39656
Splice isoforms : SwissVarP39656
Catalytic activity : Enzyme2.4.99.18 [ Enzyme-Expasy ]   2.4.99.182.4.99.18 [ IntEnz-EBI ]   2.4.99.18 [ BRENDA ]   2.4.99.18 [ KEGG ]   
PhosPhoSitePlusP39656
Domains : Interpro (EBI)DDOST_48_kDa_subunit   
Domain families : Pfam (Sanger)DDOST_48kD (PF03345)   
Domain families : Pfam (NCBI)pfam03345   
Conserved Domain (NCBI)DDOST
DMDM Disease mutations1650
Blocks (Seattle)DDOST
SuperfamilyP39656
Human Protein AtlasENSG00000244038
Peptide AtlasP39656
HPRD03728
IPIIPI00297084   IPI00910419   
Protein Interaction databases
DIP (DOE-UCLA)P39656
IntAct (EBI)P39656
FunCoupENSG00000244038
BioGRIDDDOST
STRING (EMBL)DDOST
ZODIACDDOST
Ontologies - Pathways
QuickGOP39656
Ontology : AmiGOoligosaccharyl transferase activity  dolichyl-diphosphooligosaccharide-protein glycotransferase activity  dolichyl-diphosphooligosaccharide-protein glycotransferase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  protein glycosylation  protein N-linked glycosylation  oligosaccharyltransferase complex  oligosaccharyltransferase complex  membrane  integral component of membrane  protein N-linked glycosylation via asparagine  protein N-linked glycosylation via asparagine  response to cytokine  azurophil granule membrane  T cell activation  intracellular membrane-bounded organelle  protein complex  neutrophil degranulation  
Ontology : EGO-EBIoligosaccharyl transferase activity  dolichyl-diphosphooligosaccharide-protein glycotransferase activity  dolichyl-diphosphooligosaccharide-protein glycotransferase activity  protein binding  endoplasmic reticulum  endoplasmic reticulum membrane  plasma membrane  protein glycosylation  protein N-linked glycosylation  oligosaccharyltransferase complex  oligosaccharyltransferase complex  membrane  integral component of membrane  protein N-linked glycosylation via asparagine  protein N-linked glycosylation via asparagine  response to cytokine  azurophil granule membrane  T cell activation  intracellular membrane-bounded organelle  protein complex  neutrophil degranulation  
Pathways : KEGGN-Glycan biosynthesis    Protein processing in endoplasmic reticulum   
NDEx NetworkDDOST
Atlas of Cancer Signalling NetworkDDOST
Wikipedia pathwaysDDOST
Orthology - Evolution
OrthoDB1650
GeneTree (enSembl)ENSG00000244038
Phylogenetic Trees/Animal Genes : TreeFamDDOST
HOVERGENP39656
HOGENOMP39656
Homologs : HomoloGeneDDOST
Homology/Alignments : Family Browser (UCSC)DDOST
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDOST [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDOST
dbVarDDOST
ClinVarDDOST
1000_GenomesDDOST 
Exome Variant ServerDDOST
ExAC (Exome Aggregation Consortium)DDOST (select the gene name)
Genetic variants : HAPMAP1650
Genomic Variants (DGV)DDOST [DGVbeta]
DECIPHERDDOST [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDOST 
Mutations
ICGC Data PortalDDOST 
TCGA Data PortalDDOST 
Broad Tumor PortalDDOST
OASIS PortalDDOST [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDOST  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDOST
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)Mendelian genes
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
BioMutasearch DDOST
DgiDB (Drug Gene Interaction Database)DDOST
DoCM (Curated mutations)DDOST (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDOST (select a term)
intoGenDDOST
Cancer3DDDOST(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602202    614507   
Orphanet21127   
MedgenDDOST
Genetic Testing Registry DDOST
NextProtP39656 [Medical]
TSGene1650
GENETestsDDOST
Target ValidationDDOST
Huge Navigator DDOST [HugePedia]
snp3D : Map Gene to Disease1650
BioCentury BCIQDDOST
ClinGenDDOST
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1650
Chemical/Pharm GKB GenePA27195
Clinical trialDDOST
Miscellaneous
canSAR (ICR)DDOST (select the gene name)
Probes
Litterature
PubMed48 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDOST
EVEXDDOST
GoPubMedDDOST
iHOPDDOST
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Wed Jun 7 12:30:48 CEST 2017

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