Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DDRGK1 (DDRGK domain containing 1)

Identity

Other aliasC20orf116
UFBP1
dJ1187M17.3
HGNC (Hugo) DDRGK1
LocusID (NCBI) 65992
Atlas_Id 56686
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 3190350 and ends at 3204697 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
COL18A1 (21q22.3) / DDRGK1 (20p13)DDRGK1 (20p13) / SLFNL1 (1p34.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDRGK1   16110
Cards
Entrez_Gene (NCBI)DDRGK1  65992  DDRGK domain containing 1
AliasesC20orf116; UFBP1; dJ1187M17.3
GeneCards (Weizmann)DDRGK1
Ensembl hg19 (Hinxton) [Gene_View]
Ensembl hg38 (Hinxton) [Gene_View]  chr20:3190350-3204697 [Contig_View]  DDRGK1 [Vega]
TCGA cBioPortalDDRGK1
AceView (NCBI)DDRGK1
Genatlas (Paris)DDRGK1
WikiGenes65992
SOURCE (Princeton)DDRGK1
Genetics Home Reference (NIH)DDRGK1
Genomic and cartography
GoldenPath hg38 (UCSC)DDRGK1  -     chr20:3190350-3204697 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDRGK1  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblDDRGK1 - 20p13 [CytoView hg19]  DDRGK1 - 20p13 [CytoView hg38]
Mapping of homologs : NCBIDDRGK1 [Mapview hg19]  DDRGK1 [Mapview hg38]
OMIM616177   
Gene and transcription
Genbank (Entrez)AF086090 AK310809 BC000643 BC007957 BC011851
RefSeq transcript (Entrez)NM_023935
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDRGK1
Cluster EST : UnigeneHs.471975 [ NCBI ]
CGAP (NCI)Hs.471975
Gene ExpressionDDRGK1 [ NCBI-GEO ]   DDRGK1 [ EBI - ARRAY_EXPRESS ]   DDRGK1 [ SEEK ]   DDRGK1 [ MEM ]
Gene Expression Viewer (FireBrowse)DDRGK1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)65992
GTEX Portal (Tissue expression)DDRGK1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96HY6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96HY6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96HY6
Splice isoforms : SwissVarQ96HY6
PhosPhoSitePlusQ96HY6
Domains : Interpro (EBI)DDRGK_dom-contain    WHTH_DNA-bd_dom   
Domain families : Pfam (Sanger)DDRGK (PF09756)   
Domain families : Pfam (NCBI)pfam09756   
Domain families : Smart (EMBL)DDRGK (SM01128)  
Conserved Domain (NCBI)DDRGK1
DMDM Disease mutations65992
Blocks (Seattle)DDRGK1
SuperfamilyQ96HY6
Peptide AtlasQ96HY6
IPIIPI00028387   IPI00375407   
Protein Interaction databases
DIP (DOE-UCLA)Q96HY6
IntAct (EBI)Q96HY6
BioGRIDDDRGK1
STRING (EMBL)DDRGK1
ZODIACDDRGK1
Ontologies - Pathways
QuickGOQ96HY6
Ontology : AmiGORNA polymerase II repressing transcription factor binding  protein binding  nucleolus  cytoplasm  endoplasmic reticulum  endoplasmic reticulum membrane  positive regulation of cell proliferation  positive regulation of gene expression  negative regulation of gene expression  positive regulation of cell migration  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  regulation of intracellular estrogen receptor signaling pathway  response to endoplasmic reticulum stress  negative regulation of apoptotic process  ubiquitin-like protein ligase binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of NF-kappaB transcription factor activity  positive regulation of proteasomal protein catabolic process  positive regulation of cell cycle G1/S phase transition  positive regulation of I-kappaB phosphorylation  positive regulation of metallopeptidase activity  positive regulation of protein localization to endoplasmic reticulum  positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding  protein K69-linked ufmylation  
Ontology : EGO-EBIRNA polymerase II repressing transcription factor binding  protein binding  nucleolus  cytoplasm  endoplasmic reticulum  endoplasmic reticulum membrane  positive regulation of cell proliferation  positive regulation of gene expression  negative regulation of gene expression  positive regulation of cell migration  positive regulation of proteasomal ubiquitin-dependent protein catabolic process  regulation of intracellular estrogen receptor signaling pathway  response to endoplasmic reticulum stress  negative regulation of apoptotic process  ubiquitin-like protein ligase binding  positive regulation of transcription from RNA polymerase II promoter  positive regulation of NF-kappaB transcription factor activity  positive regulation of proteasomal protein catabolic process  positive regulation of cell cycle G1/S phase transition  positive regulation of I-kappaB phosphorylation  positive regulation of metallopeptidase activity  positive regulation of protein localization to endoplasmic reticulum  positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding  protein K69-linked ufmylation  
NDEx NetworkDDRGK1
Atlas of Cancer Signalling NetworkDDRGK1
Wikipedia pathwaysDDRGK1
Orthology - Evolution
OrthoDB65992
Phylogenetic Trees/Animal Genes : TreeFamDDRGK1
HOVERGENQ96HY6
HOGENOMQ96HY6
Homologs : HomoloGeneDDRGK1
Homology/Alignments : Family Browser (UCSC)DDRGK1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDRGK1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDRGK1
dbVarDDRGK1
ClinVarDDRGK1
1000_GenomesDDRGK1 
Exome Variant ServerDDRGK1
ExAC (Exome Aggregation Consortium)DDRGK1 (select the gene name)
Genetic variants : HAPMAP65992
Genomic Variants (DGV)DDRGK1 [DGVbeta]
DECIPHERDDRGK1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDRGK1 
Mutations
ICGC Data PortalDDRGK1 
TCGA Data PortalDDRGK1 
Broad Tumor PortalDDRGK1
OASIS PortalDDRGK1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDRGK1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDRGK1
BioMutasearch DDRGK1
DgiDB (Drug Gene Interaction Database)DDRGK1
DoCM (Curated mutations)DDRGK1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDRGK1 (select a term)
intoGenDDRGK1
Cancer3DDDRGK1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616177   
Orphanet
MedgenDDRGK1
Genetic Testing Registry DDRGK1
NextProtQ96HY6 [Medical]
TSGene65992
GENETestsDDRGK1
Huge Navigator DDRGK1 [HugePedia]
snp3D : Map Gene to Disease65992
BioCentury BCIQDDRGK1
ClinGenDDRGK1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD65992
Chemical/Pharm GKB GenePA164718734
Clinical trialDDRGK1
Miscellaneous
canSAR (ICR)DDRGK1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDRGK1
EVEXDDRGK1
GoPubMedDDRGK1
iHOPDDRGK1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri May 19 12:12:55 CEST 2017

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