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DDX20 (DEAD-box helicase 20)

Identity

Alias_namesDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 20, 103kD
DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
Alias_symbol (synonym)DP103
GEMIN3
Other alias
HGNC (Hugo) DDX20
LocusID (NCBI) 11218
Atlas_Id 47213
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 112298190 and ends at 112310199 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DDX20 (1p13.2) / TBX15 (1p12)DDX20 1p13.2 / TBX15 1p12

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDX20   2743
Cards
Entrez_Gene (NCBI)DDX20  11218  DEAD-box helicase 20
AliasesDP103; GEMIN3
GeneCards (Weizmann)DDX20
Ensembl hg19 (Hinxton)ENSG00000064703 [Gene_View]  chr1:112298190-112310199 [Contig_View]  DDX20 [Vega]
Ensembl hg38 (Hinxton)ENSG00000064703 [Gene_View]  chr1:112298190-112310199 [Contig_View]  DDX20 [Vega]
ICGC DataPortalENSG00000064703
TCGA cBioPortalDDX20
AceView (NCBI)DDX20
Genatlas (Paris)DDX20
WikiGenes11218
SOURCE (Princeton)DDX20
Genetics Home Reference (NIH)DDX20
Genomic and cartography
GoldenPath hg19 (UCSC)DDX20  -     chr1:112298190-112310199 +  1p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DDX20  -     1p13.2   [Description]    (hg38-Dec_2013)
EnsemblDDX20 - 1p13.2 [CytoView hg19]  DDX20 - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBIDDX20 [Mapview hg19]  DDX20 [Mapview hg38]
OMIM606168   
Gene and transcription
Genbank (Entrez)AF106019 AF155803 AF171063 AK001506 AK301697
RefSeq transcript (Entrez)NM_007204
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929290
Consensus coding sequences : CCDS (NCBI)DDX20
Cluster EST : UnigeneHs.591405 [ NCBI ]
CGAP (NCI)Hs.591405
Alternative Splicing GalleryENSG00000064703
Gene ExpressionDDX20 [ NCBI-GEO ]   DDX20 [ EBI - ARRAY_EXPRESS ]   DDX20 [ SEEK ]   DDX20 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX20 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)11218
GTEX Portal (Tissue expression)DDX20
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHI6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHI6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHI6
Splice isoforms : SwissVarQ9UHI6
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ9UHI6
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX20
DMDM Disease mutations11218
Blocks (Seattle)DDX20
PDB (SRS)2OXC    3B7G   
PDB (PDBSum)2OXC    3B7G   
PDB (IMB)2OXC    3B7G   
PDB (RSDB)2OXC    3B7G   
Structural Biology KnowledgeBase2OXC    3B7G   
SCOP (Structural Classification of Proteins)2OXC    3B7G   
CATH (Classification of proteins structures)2OXC    3B7G   
SuperfamilyQ9UHI6
Human Protein AtlasENSG00000064703
Peptide AtlasQ9UHI6
HPRD05859
IPIIPI00005904   IPI00982671   IPI00982035   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHI6
IntAct (EBI)Q9UHI6
FunCoupENSG00000064703
BioGRIDDDX20
STRING (EMBL)DDX20
ZODIACDDX20
Ontologies - Pathways
QuickGOQ9UHI6
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  spliceosomal tri-snRNP complex assembly  spliceosomal snRNP assembly  spliceosomal snRNP assembly  DNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  cytoskeleton  RNA processing  negative regulation of cell proliferation  RNA secondary structure unwinding  membrane  protein domain specific binding  protein binding, bridging  SMN complex  SMN-Sm protein complex  histone deacetylase binding  positive regulation of apoptotic process  positive regulation of apoptotic process  oogenesis  regulation of steroid biosynthetic process  nuclear import  repressing transcription factor binding  RNA polymerase II transcription repressor complex  Gemini of coiled bodies  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  spliceosomal tri-snRNP complex assembly  spliceosomal snRNP assembly  spliceosomal snRNP assembly  DNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  cytoplasm  cytosol  cytosol  cytoskeleton  RNA processing  negative regulation of cell proliferation  RNA secondary structure unwinding  membrane  protein domain specific binding  protein binding, bridging  SMN complex  SMN-Sm protein complex  histone deacetylase binding  positive regulation of apoptotic process  positive regulation of apoptotic process  oogenesis  regulation of steroid biosynthetic process  nuclear import  repressing transcription factor binding  RNA polymerase II transcription repressor complex  Gemini of coiled bodies  
Pathways : BIOCARTAMETS affect on Macrophage Differentiation [Genes]   
Pathways : KEGGRNA transport   
NDEx NetworkDDX20
Atlas of Cancer Signalling NetworkDDX20
Wikipedia pathwaysDDX20
Orthology - Evolution
OrthoDB11218
GeneTree (enSembl)ENSG00000064703
Phylogenetic Trees/Animal Genes : TreeFamDDX20
HOVERGENQ9UHI6
HOGENOMQ9UHI6
Homologs : HomoloGeneDDX20
Homology/Alignments : Family Browser (UCSC)DDX20
Gene fusions - Rearrangements
Fusion : MitelmanDDX20/TBX15 [1p13.2/1p12]  
Fusion: TCGADDX20 1p13.2 TBX15 1p12 LAML
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX20 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX20
dbVarDDX20
ClinVarDDX20
1000_GenomesDDX20 
Exome Variant ServerDDX20
ExAC (Exome Aggregation Consortium)DDX20 (select the gene name)
Genetic variants : HAPMAP11218
Genomic Variants (DGV)DDX20 [DGVbeta]
DECIPHER (Syndromes)1:112298190-112310199  ENSG00000064703
CONAN: Copy Number AnalysisDDX20 
Mutations
ICGC Data PortalDDX20 
TCGA Data PortalDDX20 
Broad Tumor PortalDDX20
OASIS PortalDDX20 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX20  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX20
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDX20
DgiDB (Drug Gene Interaction Database)DDX20
DoCM (Curated mutations)DDX20 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX20 (select a term)
intoGenDDX20
Cancer3DDDX20(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606168   
Orphanet
MedgenDDX20
Genetic Testing Registry DDX20
NextProtQ9UHI6 [Medical]
TSGene11218
GENETestsDDX20
Huge Navigator DDX20 [HugePedia]
snp3D : Map Gene to Disease11218
BioCentury BCIQDDX20
ClinGenDDX20
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD11218
Chemical/Pharm GKB GenePA27209
Clinical trialDDX20
Miscellaneous
canSAR (ICR)DDX20 (select the gene name)
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX20
EVEXDDX20
GoPubMedDDX20
iHOPDDX20
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

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indexed on : Tue Mar 14 13:02:56 CET 2017

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