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DDX23 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 23)

Identity

Other namesPRPF28
U5-100K
U5-100KD
prp28
HGNC (Hugo) DDX23
LocusID (NCBI) 9416
Location 12q13.12
Location_base_pair Starts at 49223539 and ends at 49245957 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DDX23   17347
Entrez_Gene (NCBI)DDX23  9416  DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
Cards
GeneCards (Weizmann)DDX23
Ensembl (Hinxton)ENSG00000174243 [Gene_View]  chr12:49223539-49245957 [Contig_View]  DDX23 [Vega]
AceView (NCBI)DDX23
Genatlas (Paris)DDX23
SOURCE (Stanford)NM_004818
Genomic and cartography
GoldenPath (UCSC)DDX23  -  12q13.12   chr12:49223539-49245957 -  12q13.12   [Description]    (hg19-Feb_2009)
EnsemblDDX23 - 12q13.12 [CytoView]
Mapping of homologs : NCBIDDX23 [Mapview]
OMIM612172   
Gene and transcription
Genbank (Entrez)AF026402 AK128428 AK292921 AK294877 AK312379
RefSeq transcript (SRS)NM_004818
RefSeq transcript (Entrez)NM_004818
RefSeq genomic (SRS)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004078075
RefSeq genomic (Entrez)AC_000144 NC_000012 NC_018923 NT_029419 NW_001838057 NW_004078075
Consensus coding sequences : CCDS (NCBI)DDX23
Cluster EST : UnigeneHs.130098 [ SRS ] Hs.130098 [ NCBI ]
CGAP (NCI)Hs.130098
Alternative Splicing : Fast-db (Paris)GSHG0007428
Alternative Splicing GalleryENSG00000174243
Gene ExpressionDDX23 [ NCBI-GEO ]   DDX23 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BUQ8 (SRS) Q9BUQ8 (Uniprot)
NextProtQ9BUQ8
With graphics : InterProQ9BUQ8
Splice isoforms : SwissVarQ9BUQ8(Swissvar)
Domaine pattern : Prosite (SRS)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (SRS)DNA/RNA_helicase_DEAD/DEAH_N    Helicase_ATP-bd    Helicase_C    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Domains : Interpro (EBI)DNA/RNA_helicase_DEAD/DEAH_N    Helicase_ATP-bd    Helicase_C    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Related proteins : CluSTrQ9BUQ8
Domain families : Pfam (SRS)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
DMDM9416
Blocks (Seattle)Q9BUQ8
Human Protein AtlasENSG00000174243
HPRD09908
IPIIPI00006725   IPI00903057   IPI01021148   IPI01020725   IPI01021504   IPI01020999   IPI01021791   
Protein Interaction databases
DIP (DOE-UCLA)Q9BUQ8
IntAct (EBI)Q9BUQ8
FunCoupENSG00000174243
REACTOMEDDX23
Protein Interaction Database9416
BioGRIDDDX23
InParanoidQ9BUQ8
Interologous Interaction database Q9BUQ8
IntegromeDBDDX23
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DDX23
SNP (GeneSNP Utah)DDX23
SNP : HGBaseDDX23
Genetic variants : HAPMAPDDX23
Somatic Mutations in Cancer : COSMICDDX23 
CONAN: Copy Number AnalysisDDX23 
Mutations and Diseases : HGMDDDX23
OMIM612172   
GENETests612172   
Disease Genetic AssociationDDX23
Huge Navigator DDX23 [HugePedia]  DDX23 [HugeCancerGEM]
Genomic VariantsDDX23  DDX23 [DGVbeta]
snp3D : Map Gene to Disease9416
General knowledge
Homologs : HomoloGeneDDX23
Homology/Alignments : Family Browser (UCSC)DDX23
Phylogenetic Trees/Animal Genes : TreeFamDDX23
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.13 [ Enzyme-SRS ]   3.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
Chemical/Protein Interactions : CTD9416
Chemical/Pharm GKB GenePA134934941
Clinical trialDDX23
Cancer Resource (Charite)ENSG00000174243
Ontology : AmiGOcis assembly of pre-catalytic spliceosome  RNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  nucleic acid binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  U5 snRNP  nucleolus  mitochondrion  plasma membrane  ATP-dependent helicase activity  RNA splicing  gene expression  catalytic step 2 spliceosome  
Ontology : EGO-EBIcis assembly of pre-catalytic spliceosome  RNA splicing, via transesterification reactions  mRNA splicing, via spliceosome  mRNA splicing, via spliceosome  nucleic acid binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  U5 snRNP  nucleolus  mitochondrion  plasma membrane  ATP-dependent helicase activity  RNA splicing  gene expression  catalytic step 2 spliceosome  
Pathways : KEGGFolate biosynthesisStarch and sucrose metabolism
Other databases
Probes
Litterature
PubMed33 Pubmed reference(s) in Entrez
PubGeneDDX23
iHOPDDX23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:28:38 CEST 2013
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