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DDX28 (DEAD-box helicase 28)

Identity

Alias_namesDEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 28
DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
Alias_symbol (synonym)MDDX28
FLJ11282
Other alias
HGNC (Hugo) DDX28
LocusID (NCBI) 55794
Atlas_Id 47481
Location 16q22.1  [Link to chromosome band 16q22]
Location_base_pair Starts at 68055177 and ends at 68057770 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDX28   17330
Cards
Entrez_Gene (NCBI)DDX28  55794  DEAD-box helicase 28
AliasesMDDX28
GeneCards (Weizmann)DDX28
Ensembl hg19 (Hinxton)ENSG00000182810 [Gene_View]  chr16:68055177-68057770 [Contig_View]  DDX28 [Vega]
Ensembl hg38 (Hinxton)ENSG00000182810 [Gene_View]  chr16:68055177-68057770 [Contig_View]  DDX28 [Vega]
ICGC DataPortalENSG00000182810
TCGA cBioPortalDDX28
AceView (NCBI)DDX28
Genatlas (Paris)DDX28
WikiGenes55794
SOURCE (Princeton)DDX28
Genetics Home Reference (NIH)DDX28
Genomic and cartography
GoldenPath hg19 (UCSC)DDX28  -     chr16:68055177-68057770 -  16q22.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DDX28  -     16q22.1   [Description]    (hg38-Dec_2013)
EnsemblDDX28 - 16q22.1 [CytoView hg19]  DDX28 - 16q22.1 [CytoView hg38]
Mapping of homologs : NCBIDDX28 [Mapview hg19]  DDX28 [Mapview hg38]
OMIM607618   
Gene and transcription
Genbank (Entrez)AK002144 BC014517 BC024273 BM671594 CF993871
RefSeq transcript (Entrez)NM_018380
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_010498 NW_004929402
Consensus coding sequences : CCDS (NCBI)DDX28
Cluster EST : UnigeneHs.458313 [ NCBI ]
CGAP (NCI)Hs.458313
Alternative Splicing GalleryENSG00000182810
Gene ExpressionDDX28 [ NCBI-GEO ]   DDX28 [ EBI - ARRAY_EXPRESS ]   DDX28 [ SEEK ]   DDX28 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX28 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55794
GTEX Portal (Tissue expression)DDX28
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NUL7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NUL7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NUL7
Splice isoforms : SwissVarQ9NUL7
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ9NUL7
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    RNA_helicase_DEAD_Q_motif   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX28
DMDM Disease mutations55794
Blocks (Seattle)DDX28
SuperfamilyQ9NUL7
Human Protein AtlasENSG00000182810
Peptide AtlasQ9NUL7
HPRD06357
IPIIPI00020050   
Protein Interaction databases
DIP (DOE-UCLA)Q9NUL7
IntAct (EBI)Q9NUL7
FunCoupENSG00000182810
BioGRIDDDX28
STRING (EMBL)DDX28
ZODIACDDX28
Ontologies - Pathways
QuickGOQ9NUL7
Ontology : AmiGOATP-dependent RNA helicase activity  ATP binding  nucleus  nucleolus  cytoplasm  mitochondrion  RNA secondary structure unwinding  rRNA binding  ribonucleoprotein granule  mitochondrial nucleoid  poly(A) RNA binding  mitochondrial large ribosomal subunit assembly  
Ontology : EGO-EBIATP-dependent RNA helicase activity  ATP binding  nucleus  nucleolus  cytoplasm  mitochondrion  RNA secondary structure unwinding  rRNA binding  ribonucleoprotein granule  mitochondrial nucleoid  poly(A) RNA binding  mitochondrial large ribosomal subunit assembly  
NDEx NetworkDDX28
Atlas of Cancer Signalling NetworkDDX28
Wikipedia pathwaysDDX28
Orthology - Evolution
OrthoDB55794
GeneTree (enSembl)ENSG00000182810
Phylogenetic Trees/Animal Genes : TreeFamDDX28
HOVERGENQ9NUL7
HOGENOMQ9NUL7
Homologs : HomoloGeneDDX28
Homology/Alignments : Family Browser (UCSC)DDX28
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX28 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX28
dbVarDDX28
ClinVarDDX28
1000_GenomesDDX28 
Exome Variant ServerDDX28
ExAC (Exome Aggregation Consortium)DDX28 (select the gene name)
Genetic variants : HAPMAP55794
Genomic Variants (DGV)DDX28 [DGVbeta]
DECIPHER (Syndromes)16:68055177-68057770  ENSG00000182810
CONAN: Copy Number AnalysisDDX28 
Mutations
ICGC Data PortalDDX28 
TCGA Data PortalDDX28 
Broad Tumor PortalDDX28
OASIS PortalDDX28 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX28  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX28
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DDX28
DgiDB (Drug Gene Interaction Database)DDX28
DoCM (Curated mutations)DDX28 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX28 (select a term)
intoGenDDX28
Cancer3DDDX28(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607618   
Orphanet
MedgenDDX28
Genetic Testing Registry DDX28
NextProtQ9NUL7 [Medical]
TSGene55794
GENETestsDDX28
Huge Navigator DDX28 [HugePedia]
snp3D : Map Gene to Disease55794
BioCentury BCIQDDX28
ClinGenDDX28
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55794
Chemical/Pharm GKB GenePA27214
Clinical trialDDX28
Miscellaneous
canSAR (ICR)DDX28 (select the gene name)
Probes
Litterature
PubMed28 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX28
EVEXDDX28
GoPubMedDDX28
iHOPDDX28
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:58:36 CEST 2017

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