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DDX31 (DEAD-box helicase 31)

Identity

Alias_namesregulatory subunit 25
Alias_symbol (synonym)FLJ13633
FLJ23349
FLJ14578
PPP1R25
Other alias
HGNC (Hugo) DDX31
LocusID (NCBI) 64794
Atlas_Id 46668
Location 9q34.13  [Link to chromosome band 9q34]
Location_base_pair Starts at 132592997 and ends at 132670401 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DDX31 (9q34.13) / AK8 (9q34.13)FANCC (9q22.32) / DDX31 (9q34.13)DDX31 9q34.13 / AK8 9q34.13
FANCC 9q22.32 / DDX31 9q34.13

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDX31   16715
Cards
Entrez_Gene (NCBI)DDX31  64794  DEAD-box helicase 31
AliasesPPP1R25
GeneCards (Weizmann)DDX31
Ensembl hg19 (Hinxton)ENSG00000125485 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000125485 [Gene_View]  chr9:132592997-132670401 [Contig_View]  DDX31 [Vega]
ICGC DataPortalENSG00000125485
TCGA cBioPortalDDX31
AceView (NCBI)DDX31
Genatlas (Paris)DDX31
WikiGenes64794
SOURCE (Princeton)DDX31
Genetics Home Reference (NIH)DDX31
Genomic and cartography
GoldenPath hg38 (UCSC)DDX31  -     chr9:132592997-132670401 -  9q34.13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDX31  -     9q34.13   [Description]    (hg19-Feb_2009)
EnsemblDDX31 - 9q34.13 [CytoView hg19]  DDX31 - 9q34.13 [CytoView hg38]
Mapping of homologs : NCBIDDX31 [Mapview hg19]  DDX31 [Mapview hg38]
OMIM616533   
Gene and transcription
Genbank (Entrez)AF335567 AF335568 AF335569 AF427339 AK023695
RefSeq transcript (Entrez)NM_001322340 NM_001322341 NM_001322342 NM_001322343 NM_001322344 NM_022779 NM_138620
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDX31
Cluster EST : UnigeneHs.660767 [ NCBI ]
CGAP (NCI)Hs.660767
Alternative Splicing GalleryENSG00000125485
Gene ExpressionDDX31 [ NCBI-GEO ]   DDX31 [ EBI - ARRAY_EXPRESS ]   DDX31 [ SEEK ]   DDX31 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX31 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)64794
GTEX Portal (Tissue expression)DDX31
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H8H2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H8H2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H8H2
Splice isoforms : SwissVarQ9H8H2
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ9H8H2
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DUF4217    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Domain families : Pfam (Sanger)DEAD (PF00270)    DUF4217 (PF13959)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam13959    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  DUF4217 (SM01178)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX31
DMDM Disease mutations64794
Blocks (Seattle)DDX31
SuperfamilyQ9H8H2
Human Protein AtlasENSG00000125485
Peptide AtlasQ9H8H2
HPRD10860
IPIIPI00043990   IPI00291296   IPI00552374   IPI00552716   IPI00910952   IPI01010837   IPI00844181   
Protein Interaction databases
DIP (DOE-UCLA)Q9H8H2
IntAct (EBI)Q9H8H2
FunCoupENSG00000125485
BioGRIDDDX31
STRING (EMBL)DDX31
ZODIACDDX31
Ontologies - Pathways
QuickGOQ9H8H2
Ontology : AmiGORNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleolus  Golgi apparatus  RNA secondary structure unwinding  ribosome biogenesis  intracellular membrane-bounded organelle  
Ontology : EGO-EBIRNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleolus  Golgi apparatus  RNA secondary structure unwinding  ribosome biogenesis  intracellular membrane-bounded organelle  
NDEx NetworkDDX31
Atlas of Cancer Signalling NetworkDDX31
Wikipedia pathwaysDDX31
Orthology - Evolution
OrthoDB64794
GeneTree (enSembl)ENSG00000125485
Phylogenetic Trees/Animal Genes : TreeFamDDX31
HOVERGENQ9H8H2
HOGENOMQ9H8H2
Homologs : HomoloGeneDDX31
Homology/Alignments : Family Browser (UCSC)DDX31
Gene fusions - Rearrangements
Fusion : MitelmanDDX31/AK8 [9q34.13/9q34.13]  
Fusion : MitelmanFANCC/DDX31 [9q22.32/9q34.13]  [t(9;9)(q22;q34)]  
Fusion: TCGADDX31 9q34.13 AK8 9q34.13 BRCA
Fusion: TCGAFANCC 9q22.32 DDX31 9q34.13 LGG
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX31 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX31
dbVarDDX31
ClinVarDDX31
1000_GenomesDDX31 
Exome Variant ServerDDX31
ExAC (Exome Aggregation Consortium)DDX31 (select the gene name)
Genetic variants : HAPMAP64794
Genomic Variants (DGV)DDX31 [DGVbeta]
DECIPHERDDX31 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDX31 
Mutations
ICGC Data PortalDDX31 
TCGA Data PortalDDX31 
Broad Tumor PortalDDX31
OASIS PortalDDX31 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX31  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX31
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDX31
DgiDB (Drug Gene Interaction Database)DDX31
DoCM (Curated mutations)DDX31 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX31 (select a term)
intoGenDDX31
Cancer3DDDX31(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM616533   
Orphanet
MedgenDDX31
Genetic Testing Registry DDX31
NextProtQ9H8H2 [Medical]
TSGene64794
GENETestsDDX31
Target ValidationDDX31
Huge Navigator DDX31 [HugePedia]
snp3D : Map Gene to Disease64794
BioCentury BCIQDDX31
ClinGenDDX31
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD64794
Chemical/Pharm GKB GenePA27218
Clinical trialDDX31
Miscellaneous
canSAR (ICR)DDX31 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX31
EVEXDDX31
GoPubMedDDX31
iHOPDDX31
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:51:26 CEST 2017

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