DDX3Y (DEAD-box helicase 3 Y-linked)

2007-04-01  

Identity

HGNC
LOCATION
Yq11.221
LOCUSID
ALIAS
DBY
FUSION GENES

Other Information

Locus ID:

NCBI: 8653
MIM: 400010
HGNC: 2699
Ensembl: ENSG00000067048

Variants:

dbSNP: 8653
ClinVar: 8653
TCGA: ENSG00000067048
COSMIC: DDX3Y

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000067048ENST00000336079O15523
ENSG00000067048ENST00000336079A0A024R9A4
ENSG00000067048ENST00000360160O15523
ENSG00000067048ENST00000360160A0A024R9A4
ENSG00000067048ENST00000440554C9J081
ENSG00000067048ENST00000454054C9J8G5

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
382179532024Antioncogenic roles of USP9Y and DDX3Y in lung cancer: USP9Y stabilizes DDX3Y by preventing its degradation through deubiquitination.1
382179532024Antioncogenic roles of USP9Y and DDX3Y in lung cancer: USP9Y stabilizes DDX3Y by preventing its degradation through deubiquitination.1
369976032023DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia.3
373638592023Antibody-mediated pathogenesis of chronic GVHD through DBY/HLA class II complexes and induction of a GVL effect.1
369976032023DDX3Y is likely the key spermatogenic factor in the AZFa region that contributes to human non-obstructive azoospermia.3
373638592023Antibody-mediated pathogenesis of chronic GVHD through DBY/HLA class II complexes and induction of a GVL effect.1
355887482022Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation.20
356241152022AZFa Y gene, DDX3Y, evolved novel testis transcript variants in primates with proximal 3´UTR polyadenylation for germ cell specific translation.0
355887482022Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation.20
356241152022AZFa Y gene, DDX3Y, evolved novel testis transcript variants in primates with proximal 3´UTR polyadenylation for germ cell specific translation.0
344378372021Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.23
344378372021Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.23
316969862020MicroRNA-497 functions as an inflammatory suppressor via targeting DDX3Y and modulating toll-like receptor 4/NF-κB in cigarette smoke extract-stimulated human bronchial epithelial cells.3
327920672020Sex matters: XIST and DDX3Y gene expression as a tool to determine fetal sex in human first trimester placenta.11
316969862020MicroRNA-497 functions as an inflammatory suppressor via targeting DDX3Y and modulating toll-like receptor 4/NF-κB in cigarette smoke extract-stimulated human bronchial epithelial cells.3

Citation

Dessen P

DDX3Y (DEAD-box helicase 3 Y-linked)

Atlas Genet Cytogenet Oncol Haematol. 2007-04-01

Online version: http://atlasgeneticsoncology.org/gene/46904/ddx3y