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DDX41 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 41)

Identity

Other namesABS
HGNC (Hugo) DDX41
LocusID (NCBI) 51428
Location 5q35.3
Location_base_pair Starts at 176938578 and ends at 176943967 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DDX41   18674
Entrez_Gene (NCBI)DDX41  51428  DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
Cards
GeneCards (Weizmann)DDX41
Ensembl (Hinxton)ENSG00000183258 [Gene_View]  chr5:176938578-176943967 [Contig_View]  DDX41 [Vega]
AceView (NCBI)DDX41
Genatlas (Paris)DDX41
SOURCE (Stanford)NM_016222
Genomic and cartography
GoldenPath (UCSC)DDX41  -  5q35.3   chr5:176938578-176943967 -  5q35.3   [Description]    (hg19-Feb_2009)
EnsemblDDX41 - 5q35.3 [CytoView]
Mapping of homologs : NCBIDDX41 [Mapview]
OMIM608170   
Gene and transcription
Genbank (Entrez)AF195417 AK001255 AK026117 AK027768 AK091545
RefSeq transcript (SRS)NM_016222
RefSeq transcript (Entrez)NM_016222
RefSeq genomic (SRS)AC_000137 NC_000005 NC_018916 NT_023133 NW_001838960 NW_004078025
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NT_023133 NW_001838960 NW_004078025
Consensus coding sequences : CCDS (NCBI)DDX41
Cluster EST : UnigeneHs.484288 [ SRS ] Hs.484288 [ NCBI ]
CGAP (NCI)Hs.484288
Alternative Splicing : Fast-db (Paris)GSHG0025301
Alternative Splicing GalleryENSG00000183258
Gene ExpressionDDX41 [ NCBI-GEO ]   DDX41 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJV9 (SRS) Q9UJV9 (Uniprot)
NextProtQ9UJV9
With graphics : InterProQ9UJV9
Splice isoforms : SwissVarQ9UJV9(Swissvar)
Domaine pattern : Prosite (SRS)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)    ZF_CCHC (PS50158)   
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)    ZF_CCHC (PS50158)   
Domains : Interpro (SRS)DNA/RNA_helicase_DEAD/DEAH_N    Helicase_ATP-bd    Helicase_C    RNA_helicase_DEAD_Q_motif    Znf_CCHC   
Domains : Interpro (EBI)DNA/RNA_helicase_DEAD/DEAH_N    Helicase_ATP-bd    Helicase_C    RNA_helicase_DEAD_Q_motif    Znf_CCHC   
Related proteins : CluSTrQ9UJV9
Domain families : Pfam (SRS)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  ZnF_C2HC (SM00343)  
DMDM51428
Blocks (Seattle)Q9UJV9
PDB (SRS)2P6N   
PDB (PDBSum)2P6N   
PDB (IMB)2P6N   
PDB (RSDB)2P6N   
Human Protein AtlasENSG00000183258
HPRD10490
IPIIPI00007208   IPI00964629   IPI00965385   IPI00965661   IPI00968277   IPI00964323   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJV9
IntAct (EBI)Q9UJV9
FunCoupENSG00000183258
REACTOMEDDX41
Protein Interaction Database51428
BioGRIDDDX41
InParanoidQ9UJV9
Interologous Interaction database Q9UJV9
IntegromeDBDDX41
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DDX41
SNP (GeneSNP Utah)DDX41
SNP : HGBaseDDX41
Genetic variants : HAPMAPDDX41
Somatic Mutations in Cancer : COSMICDDX41 
CONAN: Copy Number AnalysisDDX41 
Mutations and Diseases : HGMDDDX41
OMIM608170   
GENETests608170   
Disease Genetic AssociationDDX41
Huge Navigator DDX41 [HugePedia]  DDX41 [HugeCancerGEM]
Genomic VariantsDDX41  DDX41 [DGVbeta]
snp3D : Map Gene to Disease51428
General knowledge
Homologs : HomoloGeneDDX41
Homology/Alignments : Family Browser (UCSC)DDX41
Phylogenetic Trees/Animal Genes : TreeFamDDX41
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.13 [ Enzyme-SRS ]   3.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
Chemical/Protein Interactions : CTD51428
Chemical/Pharm GKB GenePA134908862
Clinical trialDDX41
Cancer Resource (Charite)ENSG00000183258
Ontology : AmiGOmRNA splicing, via spliceosome  DNA binding  RNA binding  ATP binding  nucleus  nucleolus  endoplasmic reticulum  RNA processing  apoptotic process  multicellular organismal development  ATP-dependent helicase activity  zinc ion binding  cellular response to interferon-beta  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  defense response to virus  catalytic step 2 spliceosome  
Ontology : EGO-EBImRNA splicing, via spliceosome  DNA binding  RNA binding  ATP binding  nucleus  nucleolus  endoplasmic reticulum  RNA processing  apoptotic process  multicellular organismal development  ATP-dependent helicase activity  zinc ion binding  cellular response to interferon-beta  positive regulation of transcription from RNA polymerase II promoter  metal ion binding  defense response to virus  catalytic step 2 spliceosome  
Pathways : KEGGFolate biosynthesisStarch and sucrose metabolism
Other databases
Probes
Litterature
PubMed24 Pubmed reference(s) in Entrez
PubGeneDDX41
iHOPDDX41
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:29:16 CEST 2013
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