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DDX53 (DEAD-box helicase 53)

Identity

Alias_namesDEAD (Asp-Glu-Ala-Asp) box polypeptide 53
Alias_symbol (synonym)CAGE
CT26
Other alias
HGNC (Hugo) DDX53
LocusID (NCBI) 168400
Atlas_Id 40291
Location Xp22.11  [Link to chromosome band Xp22]
Location_base_pair Starts at 22999961 and ends at 23002089 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
RPS6KA3 (Xp22.12) / DDX53 (Xp22.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Medgen
Nomenclature
HGNC (Hugo)DDX53   20083
Cards
Entrez_Gene (NCBI)DDX53  168400  DEAD-box helicase 53
AliasesCAGE; CT26
GeneCards (Weizmann)DDX53
Ensembl hg19 (Hinxton)ENSG00000184735 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184735 [Gene_View]  chrX:22999961-23002089 [Contig_View]  DDX53 [Vega]
ICGC DataPortalENSG00000184735
TCGA cBioPortalDDX53
AceView (NCBI)DDX53
Genatlas (Paris)DDX53
WikiGenes168400
SOURCE (Princeton)DDX53
Genetics Home Reference (NIH)DDX53
Genomic and cartography
GoldenPath hg38 (UCSC)DDX53  -     chrX:22999961-23002089 +  Xp22.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDX53  -     Xp22.11   [Description]    (hg19-Feb_2009)
EnsemblDDX53 - Xp22.11 [CytoView hg19]  DDX53 - Xp22.11 [CytoView hg38]
Mapping of homologs : NCBIDDX53 [Mapview hg19]  DDX53 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AY039237 BC051703 BC067878
RefSeq transcript (Entrez)NM_182699
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDX53
Cluster EST : UnigeneHs.434416 [ NCBI ]
CGAP (NCI)Hs.434416
Alternative Splicing GalleryENSG00000184735
Gene ExpressionDDX53 [ NCBI-GEO ]   DDX53 [ EBI - ARRAY_EXPRESS ]   DDX53 [ SEEK ]   DDX53 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX53 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)168400
GTEX Portal (Tissue expression)DDX53
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86TM3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86TM3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86TM3
Splice isoforms : SwissVarQ86TM3
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ86TM3
Domaine pattern : Prosite (Expaxy)DEAD_ATP_HELICASE (PS00039)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    KH_TYPE_1 (PS50084)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    Helicase_ATP-bd    Helicase_C    KH_dom    KH_dom_type_1    P-loop_NTPase    RNA-helicase_DEAD-box_CS    RNA_helicase_DEAD_Q_motif   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)    KH_1 (PF00013)   
Domain families : Pfam (NCBI)pfam00270    pfam00271    pfam00013   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  KH (SM00322)  
Conserved Domain (NCBI)DDX53
DMDM Disease mutations168400
Blocks (Seattle)DDX53
PDB (SRS)3IUY   
PDB (PDBSum)3IUY   
PDB (IMB)3IUY   
PDB (RSDB)3IUY   
Structural Biology KnowledgeBase3IUY   
SCOP (Structural Classification of Proteins)3IUY   
CATH (Classification of proteins structures)3IUY   
SuperfamilyQ86TM3
Human Protein AtlasENSG00000184735
Peptide AtlasQ86TM3
HPRD06466
IPIIPI00328813   
Protein Interaction databases
DIP (DOE-UCLA)Q86TM3
IntAct (EBI)Q86TM3
FunCoupENSG00000184735
BioGRIDDDX53
STRING (EMBL)DDX53
ZODIACDDX53
Ontologies - Pathways
QuickGOQ86TM3
Ontology : AmiGORNA binding  ATP-dependent RNA helicase activity  ATP binding  nucleus  RNA secondary structure unwinding  
Ontology : EGO-EBIRNA binding  ATP-dependent RNA helicase activity  ATP binding  nucleus  RNA secondary structure unwinding  
NDEx NetworkDDX53
Atlas of Cancer Signalling NetworkDDX53
Wikipedia pathwaysDDX53
Orthology - Evolution
OrthoDB168400
GeneTree (enSembl)ENSG00000184735
Phylogenetic Trees/Animal Genes : TreeFamDDX53
HOVERGENQ86TM3
HOGENOMQ86TM3
Homologs : HomoloGeneDDX53
Homology/Alignments : Family Browser (UCSC)DDX53
Gene fusions - Rearrangements
Fusion : MitelmanRPS6KA3/DDX53 [Xp22.12/Xp22.11]  [t(X;X)(p22;p22)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX53 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX53
dbVarDDX53
ClinVarDDX53
1000_GenomesDDX53 
Exome Variant ServerDDX53
ExAC (Exome Aggregation Consortium)DDX53 (select the gene name)
Genetic variants : HAPMAP168400
Genomic Variants (DGV)DDX53 [DGVbeta]
DECIPHERDDX53 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDX53 
Mutations
ICGC Data PortalDDX53 
TCGA Data PortalDDX53 
Broad Tumor PortalDDX53
OASIS PortalDDX53 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX53  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX53
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)X-chromosome gene database
BioMutasearch DDX53
DgiDB (Drug Gene Interaction Database)DDX53
DoCM (Curated mutations)DDX53 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX53 (select a term)
intoGenDDX53
Cancer3DDDX53(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DDX53
Genetic Testing Registry DDX53
NextProtQ86TM3 [Medical]
TSGene168400
GENETestsDDX53
Target ValidationDDX53
Huge Navigator DDX53 [HugePedia]
snp3D : Map Gene to Disease168400
BioCentury BCIQDDX53
ClinGenDDX53
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD168400
Chemical/Pharm GKB GenePA134863598
Clinical trialDDX53
Miscellaneous
canSAR (ICR)DDX53 (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX53
EVEXDDX53
GoPubMedDDX53
iHOPDDX53
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:05:04 CEST 2017

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