Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DDX59 (DEAD-box helicase 59)

Identity

Other aliasOFD5
ZNHIT5
HGNC (Hugo) DDX59
LocusID (NCBI) 83479
Atlas_Id 57307
Location 1q32.1  [Link to chromosome band 1q32]
Location_base_pair Starts at 200644037 and ends at 200669998 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
FMN2 (1q43) / DDX59 (1q32.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDX59   25360
Cards
Entrez_Gene (NCBI)DDX59  83479  DEAD-box helicase 59
AliasesOFD5; ZNHIT5
GeneCards (Weizmann)DDX59
Ensembl hg19 (Hinxton)ENSG00000118197 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118197 [Gene_View]  ENSG00000118197 [Sequence]  chr1:200644037-200669998 [Contig_View]  DDX59 [Vega]
ICGC DataPortalENSG00000118197
TCGA cBioPortalDDX59
AceView (NCBI)DDX59
Genatlas (Paris)DDX59
WikiGenes83479
SOURCE (Princeton)DDX59
Genetics Home Reference (NIH)DDX59
Genomic and cartography
GoldenPath hg38 (UCSC)DDX59  -     chr1:200644037-200669998 -  1q32.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDX59  -     1q32.1   [Description]    (hg19-Feb_2009)
EnsemblDDX59 - 1q32.1 [CytoView hg19]  DDX59 - 1q32.1 [CytoView hg38]
Mapping of homologs : NCBIDDX59 [Mapview hg19]  DDX59 [Mapview hg38]
OMIM174300   615464   
Gene and transcription
Genbank (Entrez)AK299219 AK307569 AL136611 BC014183 BC020201
RefSeq transcript (Entrez)NM_001031725 NM_001320181 NM_001320182 NM_001349799 NM_001349800 NM_001349801 NM_001349802 NM_001349803 NM_001349804 NM_031306
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDX59
Cluster EST : UnigeneHs.497332 [ NCBI ]
CGAP (NCI)Hs.497332
Alternative Splicing GalleryENSG00000118197
Gene ExpressionDDX59 [ NCBI-GEO ]   DDX59 [ EBI - ARRAY_EXPRESS ]   DDX59 [ SEEK ]   DDX59 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX59 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)83479
GTEX Portal (Tissue expression)DDX59
Human Protein AtlasENSG00000118197-DDX59 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5T1V6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5T1V6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5T1V6
Splice isoforms : SwissVarQ5T1V6
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ5T1V6
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)    Q_MOTIF (PS51195)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase    RNA_helicase_DEAD_Q_motif    Znf_HIT   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)    zf-HIT (PF04438)   
Domain families : Pfam (NCBI)pfam00270    pfam00271    pfam04438   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX59
DMDM Disease mutations83479
Blocks (Seattle)DDX59
PDB (SRS)2YQP   
PDB (PDBSum)2YQP   
PDB (IMB)2YQP   
PDB (RSDB)2YQP   
Structural Biology KnowledgeBase2YQP   
SCOP (Structural Classification of Proteins)2YQP   
CATH (Classification of proteins structures)2YQP   
SuperfamilyQ5T1V6
Human Protein Atlas [tissue]ENSG00000118197-DDX59 [tissue]
Peptide AtlasQ5T1V6
IPIIPI00217157   IPI00010449   IPI00514037   IPI00642002   IPI00513969   IPI00644851   IPI00915879   IPI00916009   
Protein Interaction databases
DIP (DOE-UCLA)Q5T1V6
IntAct (EBI)Q5T1V6
FunCoupENSG00000118197
BioGRIDDDX59
STRING (EMBL)DDX59
ZODIACDDX59
Ontologies - Pathways
QuickGOQ5T1V6
Ontology : AmiGORNA binding  helicase activity  ATP binding  intracellular  nucleus  cytoplasm  metal ion binding  
Ontology : EGO-EBIRNA binding  helicase activity  ATP binding  intracellular  nucleus  cytoplasm  metal ion binding  
NDEx NetworkDDX59
Atlas of Cancer Signalling NetworkDDX59
Wikipedia pathwaysDDX59
Orthology - Evolution
OrthoDB83479
GeneTree (enSembl)ENSG00000118197
Phylogenetic Trees/Animal Genes : TreeFamDDX59
HOVERGENQ5T1V6
HOGENOMQ5T1V6
Homologs : HomoloGeneDDX59
Homology/Alignments : Family Browser (UCSC)DDX59
Gene fusions - Rearrangements
Fusion : QuiverDDX59
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX59 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX59
dbVarDDX59
ClinVarDDX59
1000_GenomesDDX59 
Exome Variant ServerDDX59
ExAC (Exome Aggregation Consortium)ENSG00000118197
GNOMAD BrowserENSG00000118197
Varsome BrowserDDX59
Genetic variants : HAPMAP83479
Genomic Variants (DGV)DDX59 [DGVbeta]
DECIPHERDDX59 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDX59 
Mutations
ICGC Data PortalDDX59 
TCGA Data PortalDDX59 
Broad Tumor PortalDDX59
OASIS PortalDDX59 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX59  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX59
BioMutasearch DDX59
DgiDB (Drug Gene Interaction Database)DDX59
DoCM (Curated mutations)DDX59 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX59 (select a term)
intoGenDDX59
Cancer3DDDX59(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM174300    615464   
Orphanet
DisGeNETDDX59
MedgenDDX59
Genetic Testing Registry DDX59
NextProtQ5T1V6 [Medical]
TSGene83479
GENETestsDDX59
Target ValidationDDX59
Huge Navigator DDX59 [HugePedia]
snp3D : Map Gene to Disease83479
BioCentury BCIQDDX59
ClinGenDDX59
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD83479
Chemical/Pharm GKB GenePA142672000
Clinical trialDDX59
Miscellaneous
canSAR (ICR)DDX59 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX59
EVEXDDX59
GoPubMedDDX59
iHOPDDX59
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:02:03 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.