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DDX60 (DExD/H-box helicase 60)

Identity

Alias_namesDEAD (Asp-Glu-Ala-Asp) box polypeptide 60
Alias_symbol (synonym)FLJ20035
Other alias-
HGNC (Hugo) DDX60
LocusID (NCBI) 55601
Atlas_Id 62372
Location 4q32.3  [Link to chromosome band 4q32]
Location_base_pair Starts at 168216291 and ends at 168318807 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
FAM160A1 (4q31.3) / DDX60 (4q32.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DDX60   25942
Cards
Entrez_Gene (NCBI)DDX60  55601  DExD/H-box helicase 60
Aliases
GeneCards (Weizmann)DDX60
Ensembl hg19 (Hinxton)ENSG00000137628 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137628 [Gene_View]  chr4:168216291-168318807 [Contig_View]  DDX60 [Vega]
ICGC DataPortalENSG00000137628
TCGA cBioPortalDDX60
AceView (NCBI)DDX60
Genatlas (Paris)DDX60
WikiGenes55601
SOURCE (Princeton)DDX60
Genetics Home Reference (NIH)DDX60
Genomic and cartography
GoldenPath hg38 (UCSC)DDX60  -     chr4:168216291-168318807 -  4q32.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DDX60  -     4q32.3   [Description]    (hg19-Feb_2009)
EnsemblDDX60 - 4q32.3 [CytoView hg19]  DDX60 - 4q32.3 [CytoView hg38]
Mapping of homologs : NCBIDDX60 [Mapview hg19]  DDX60 [Mapview hg38]
OMIM613974   
Gene and transcription
Genbank (Entrez)AK000042 AK001649 AK026333 AK223184 AK225191
RefSeq transcript (Entrez)NM_017631
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DDX60
Cluster EST : UnigeneHs.591710 [ NCBI ]
CGAP (NCI)Hs.591710
Alternative Splicing GalleryENSG00000137628
Gene ExpressionDDX60 [ NCBI-GEO ]   DDX60 [ EBI - ARRAY_EXPRESS ]   DDX60 [ SEEK ]   DDX60 [ MEM ]
Gene Expression Viewer (FireBrowse)DDX60 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)55601
GTEX Portal (Tissue expression)DDX60
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IY21   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IY21  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IY21
Splice isoforms : SwissVarQ8IY21
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusQ8IY21
Domaine pattern : Prosite (Expaxy)HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)DEAD (PF00270)    Helicase_C (PF00271)   
Domain families : Pfam (NCBI)pfam00270    pfam00271   
Domain families : Smart (EMBL)DEXDc (SM00487)  HELICc (SM00490)  
Conserved Domain (NCBI)DDX60
DMDM Disease mutations55601
Blocks (Seattle)DDX60
SuperfamilyQ8IY21
Human Protein AtlasENSG00000137628
Peptide AtlasQ8IY21
HPRD07877
IPIIPI00217606   IPI00966068   IPI00963981   IPI00936727   
Protein Interaction databases
DIP (DOE-UCLA)Q8IY21
IntAct (EBI)Q8IY21
FunCoupENSG00000137628
BioGRIDDDX60
STRING (EMBL)DDX60
ZODIACDDX60
Ontologies - Pathways
QuickGOQ8IY21
Ontology : AmiGOdouble-stranded DNA binding  double-stranded RNA binding  single-stranded RNA binding  helicase activity  protein binding  ATP binding  cytoplasm  cytosol  response to virus  innate immune response  intermediate filament cytoskeleton  defense response to virus  positive regulation of MDA-5 signaling pathway  positive regulation of RIG-I signaling pathway  
Ontology : EGO-EBIdouble-stranded DNA binding  double-stranded RNA binding  single-stranded RNA binding  helicase activity  protein binding  ATP binding  cytoplasm  cytosol  response to virus  innate immune response  intermediate filament cytoskeleton  defense response to virus  positive regulation of MDA-5 signaling pathway  positive regulation of RIG-I signaling pathway  
NDEx NetworkDDX60
Atlas of Cancer Signalling NetworkDDX60
Wikipedia pathwaysDDX60
Orthology - Evolution
OrthoDB55601
GeneTree (enSembl)ENSG00000137628
Phylogenetic Trees/Animal Genes : TreeFamDDX60
HOVERGENQ8IY21
HOGENOMQ8IY21
Homologs : HomoloGeneDDX60
Homology/Alignments : Family Browser (UCSC)DDX60
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDDX60 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DDX60
dbVarDDX60
ClinVarDDX60
1000_GenomesDDX60 
Exome Variant ServerDDX60
ExAC (Exome Aggregation Consortium)DDX60 (select the gene name)
Genetic variants : HAPMAP55601
Genomic Variants (DGV)DDX60 [DGVbeta]
DECIPHERDDX60 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDDX60 
Mutations
ICGC Data PortalDDX60 
TCGA Data PortalDDX60 
Broad Tumor PortalDDX60
OASIS PortalDDX60 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDDX60  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDDX60
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DDX60
DgiDB (Drug Gene Interaction Database)DDX60
DoCM (Curated mutations)DDX60 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DDX60 (select a term)
intoGenDDX60
Cancer3DDDX60(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613974   
Orphanet
MedgenDDX60
Genetic Testing Registry DDX60
NextProtQ8IY21 [Medical]
TSGene55601
GENETestsDDX60
Target ValidationDDX60
Huge Navigator DDX60 [HugePedia]
snp3D : Map Gene to Disease55601
BioCentury BCIQDDX60
ClinGenDDX60
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD55601
Chemical/Pharm GKB GenePA162383444
Clinical trialDDX60
Miscellaneous
canSAR (ICR)DDX60 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDDX60
EVEXDDX60
GoPubMedDDX60
iHOPDDX60
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:00 CEST 2017

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