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DECR1 (2,4-dienoyl CoA reductase 1, mitochondrial)

Identity

Alias_namesDECR
Alias_symbol (synonym)SDR18C1
Other aliasNADPH
HGNC (Hugo) DECR1
LocusID (NCBI) 1666
Atlas_Id 62375
Location 8q21.3  [Link to chromosome band 8q21]
Location_base_pair Starts at 91013580 and ends at 91064227 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ATP6V0B (1p34.1) / DECR1 (8q21.3)RACK1 (5q35.3) / DECR1 (8q21.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DECR1   2753
Cards
Entrez_Gene (NCBI)DECR1  1666  2,4-dienoyl CoA reductase 1, mitochondrial
AliasesDECR; NADPH; SDR18C1
GeneCards (Weizmann)DECR1
Ensembl hg19 (Hinxton)ENSG00000104325 [Gene_View]  chr8:91013580-91064227 [Contig_View]  DECR1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104325 [Gene_View]  chr8:91013580-91064227 [Contig_View]  DECR1 [Vega]
ICGC DataPortalENSG00000104325
TCGA cBioPortalDECR1
AceView (NCBI)DECR1
Genatlas (Paris)DECR1
WikiGenes1666
SOURCE (Princeton)DECR1
Genetics Home Reference (NIH)DECR1
Genomic and cartography
GoldenPath hg19 (UCSC)DECR1  -     chr8:91013580-91064227 +  8q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DECR1  -     8q21.3   [Description]    (hg38-Dec_2013)
EnsemblDECR1 - 8q21.3 [CytoView hg19]  DECR1 - 8q21.3 [CytoView hg38]
Mapping of homologs : NCBIDECR1 [Mapview hg19]  DECR1 [Mapview hg38]
OMIM222745   
Gene and transcription
Genbank (Entrez)AK300069 BC105080 BC105082 BC143669 L26050
RefSeq transcript (Entrez)NM_001359
RefSeq genomic (Entrez)NC_000008 NC_018919 NG_008042 NT_008046 NW_004929340
Consensus coding sequences : CCDS (NCBI)DECR1
Cluster EST : UnigeneHs.492212 [ NCBI ]
CGAP (NCI)Hs.492212
Alternative Splicing GalleryENSG00000104325
Gene ExpressionDECR1 [ NCBI-GEO ]   DECR1 [ EBI - ARRAY_EXPRESS ]   DECR1 [ SEEK ]   DECR1 [ MEM ]
Gene Expression Viewer (FireBrowse)DECR1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1666
GTEX Portal (Tissue expression)DECR1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16698   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16698  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16698
Splice isoforms : SwissVarQ16698
Catalytic activity : Enzyme1.3.1.34 [ Enzyme-Expasy ]   1.3.1.341.3.1.34 [ IntEnz-EBI ]   1.3.1.34 [ BRENDA ]   1.3.1.34 [ KEGG ]   
PhosPhoSitePlusQ16698
Domains : Interpro (EBI)Glc/ribitol_DH    NAD(P)-bd_dom   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)DECR1
DMDM Disease mutations1666
Blocks (Seattle)DECR1
PDB (SRS)1W6U    1W73    1W8D   
PDB (PDBSum)1W6U    1W73    1W8D   
PDB (IMB)1W6U    1W73    1W8D   
PDB (RSDB)1W6U    1W73    1W8D   
Structural Biology KnowledgeBase1W6U    1W73    1W8D   
SCOP (Structural Classification of Proteins)1W6U    1W73    1W8D   
CATH (Classification of proteins structures)1W6U    1W73    1W8D   
SuperfamilyQ16698
Human Protein AtlasENSG00000104325
Peptide AtlasQ16698
HPRD01959
IPIIPI00003482   IPI00974343   IPI00973887   IPI00978507   IPI00980553   IPI00980484   IPI00979062   IPI00978478   IPI00976338   
Protein Interaction databases
DIP (DOE-UCLA)Q16698
IntAct (EBI)Q16698
FunCoupENSG00000104325
BioGRIDDECR1
STRING (EMBL)DECR1
ZODIACDECR1
Ontologies - Pathways
QuickGOQ16698
Ontology : AmiGOnucleus  nucleoplasm  cytoplasm  mitochondrion  mitochondrion  mitochondrial matrix  fatty acid beta-oxidation  fatty acid beta-oxidation  2,4-dienoyl-CoA reductase (NADPH) activity  oxidoreductase activity, acting on NAD(P)H  cellular lipid metabolic process  small molecule metabolic process  protein homotetramerization  extracellular exosome  NADPH binding  
Ontology : EGO-EBInucleus  nucleoplasm  cytoplasm  mitochondrion  mitochondrion  mitochondrial matrix  fatty acid beta-oxidation  fatty acid beta-oxidation  2,4-dienoyl-CoA reductase (NADPH) activity  oxidoreductase activity, acting on NAD(P)H  cellular lipid metabolic process  small molecule metabolic process  protein homotetramerization  extracellular exosome  NADPH binding  
NDEx NetworkDECR1
Atlas of Cancer Signalling NetworkDECR1
Wikipedia pathwaysDECR1
Orthology - Evolution
OrthoDB1666
GeneTree (enSembl)ENSG00000104325
Phylogenetic Trees/Animal Genes : TreeFamDECR1
HOVERGENQ16698
HOGENOMQ16698
Homologs : HomoloGeneDECR1
Homology/Alignments : Family Browser (UCSC)DECR1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDECR1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DECR1
dbVarDECR1
ClinVarDECR1
1000_GenomesDECR1 
Exome Variant ServerDECR1
ExAC (Exome Aggregation Consortium)DECR1 (select the gene name)
Genetic variants : HAPMAP1666
Genomic Variants (DGV)DECR1 [DGVbeta]
DECIPHER (Syndromes)8:91013580-91064227  ENSG00000104325
CONAN: Copy Number AnalysisDECR1 
Mutations
ICGC Data PortalDECR1 
TCGA Data PortalDECR1 
Broad Tumor PortalDECR1
OASIS PortalDECR1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDECR1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDECR1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DECR1
DgiDB (Drug Gene Interaction Database)DECR1
DoCM (Curated mutations)DECR1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DECR1 (select a term)
intoGenDECR1
Cancer3DDECR1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM222745   
Orphanet
MedgenDECR1
Genetic Testing Registry DECR1
NextProtQ16698 [Medical]
TSGene1666
GENETestsDECR1
Huge Navigator DECR1 [HugePedia]
snp3D : Map Gene to Disease1666
BioCentury BCIQDECR1
ClinGenDECR1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1666
Chemical/Pharm GKB GenePA141
Clinical trialDECR1
Miscellaneous
canSAR (ICR)DECR1 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDECR1
EVEXDECR1
GoPubMedDECR1
iHOPDECR1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:01:17 CET 2017

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