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DECR2 (2,4-dienoyl-CoA reductase 2)

Identity

Alias_symbol (synonym)PDCR
SDR17C1
Other alias
HGNC (Hugo) DECR2
LocusID (NCBI) 26063
Atlas_Id 62376
Location 16p13.3  [Link to chromosome band 16p13]
Location_base_pair Starts at 401858 and ends at 412487 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
DECR2 (16p13.3) / DDX10 (11q22.3)DECR2 (16p13.3) / UBA1 (Xp11.23)TSIX (Xq13.2) / DECR2 (16p13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DECR2   2754
Cards
Entrez_Gene (NCBI)DECR2  26063  2,4-dienoyl-CoA reductase 2
AliasesPDCR; SDR17C1
GeneCards (Weizmann)DECR2
Ensembl hg19 (Hinxton)ENSG00000242612 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000242612 [Gene_View]  chr16:401858-412487 [Contig_View]  DECR2 [Vega]
ICGC DataPortalENSG00000242612
TCGA cBioPortalDECR2
AceView (NCBI)DECR2
Genatlas (Paris)DECR2
WikiGenes26063
SOURCE (Princeton)DECR2
Genetics Home Reference (NIH)DECR2
Genomic and cartography
GoldenPath hg38 (UCSC)DECR2  -     chr16:401858-412487 +  16p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DECR2  -     16p13.3   [Description]    (hg19-Feb_2009)
EnsemblDECR2 - 16p13.3 [CytoView hg19]  DECR2 - 16p13.3 [CytoView hg38]
Mapping of homologs : NCBIDECR2 [Mapview hg19]  DECR2 [Mapview hg38]
OMIM615839   
Gene and transcription
Genbank (Entrez)AJ293009 AK055839 AK094340 AK128012 AK225961
RefSeq transcript (Entrez)NM_020664
RefSeq genomic (Entrez)NC_000016 NC_018927 NT_187610
Consensus coding sequences : CCDS (NCBI)DECR2
Cluster EST : UnigeneHs.628831 [ NCBI ]
CGAP (NCI)Hs.628831
Alternative Splicing GalleryENSG00000242612
Gene ExpressionDECR2 [ NCBI-GEO ]   DECR2 [ EBI - ARRAY_EXPRESS ]   DECR2 [ SEEK ]   DECR2 [ MEM ]
Gene Expression Viewer (FireBrowse)DECR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)26063
GTEX Portal (Tissue expression)DECR2
Human Protein AtlasENSG00000242612-DECR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NUI1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NUI1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NUI1
Splice isoforms : SwissVarQ9NUI1
Catalytic activity : Enzyme1.3.1.34 [ Enzyme-Expasy ]   1.3.1.341.3.1.34 [ IntEnz-EBI ]   1.3.1.34 [ BRENDA ]   1.3.1.34 [ KEGG ]   
PhosPhoSitePlusQ9NUI1
Domains : Interpro (EBI)NAD(P)-bd_dom    SDR_fam   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)DECR2
DMDM Disease mutations26063
Blocks (Seattle)DECR2
PDB (SRS)4FC6    4FC7   
PDB (PDBSum)4FC6    4FC7   
PDB (IMB)4FC6    4FC7   
PDB (RSDB)4FC6    4FC7   
Structural Biology KnowledgeBase4FC6    4FC7   
SCOP (Structural Classification of Proteins)4FC6    4FC7   
CATH (Classification of proteins structures)4FC6    4FC7   
SuperfamilyQ9NUI1
Human Protein Atlas [tissue]ENSG00000242612-DECR2 [tissue]
Peptide AtlasQ9NUI1
HPRD16789
IPIIPI00010190   IPI00444050   IPI00640806   IPI00877954   IPI00856119   IPI00894182   
Protein Interaction databases
DIP (DOE-UCLA)Q9NUI1
IntAct (EBI)Q9NUI1
FunCoupENSG00000242612
BioGRIDDECR2
STRING (EMBL)DECR2
ZODIACDECR2
Ontologies - Pathways
QuickGOQ9NUI1
Ontology : AmiGOreceptor binding  peroxisomal membrane  unsaturated fatty acid biosynthetic process  2,4-dienoyl-CoA reductase (NADPH) activity  trans-2-enoyl-CoA reductase (NADPH) activity  trans-2-enoyl-CoA reductase (NADPH) activity  cellular lipid metabolic process  oxidation-reduction process  
Ontology : EGO-EBIreceptor binding  peroxisomal membrane  unsaturated fatty acid biosynthetic process  2,4-dienoyl-CoA reductase (NADPH) activity  trans-2-enoyl-CoA reductase (NADPH) activity  trans-2-enoyl-CoA reductase (NADPH) activity  cellular lipid metabolic process  oxidation-reduction process  
Pathways : KEGGPeroxisome   
NDEx NetworkDECR2
Atlas of Cancer Signalling NetworkDECR2
Wikipedia pathwaysDECR2
Orthology - Evolution
OrthoDB26063
GeneTree (enSembl)ENSG00000242612
Phylogenetic Trees/Animal Genes : TreeFamDECR2
HOVERGENQ9NUI1
HOGENOMQ9NUI1
Homologs : HomoloGeneDECR2
Homology/Alignments : Family Browser (UCSC)DECR2
Gene fusions - Rearrangements
Tumor Fusion PortalDECR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDECR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DECR2
dbVarDECR2
ClinVarDECR2
1000_GenomesDECR2 
Exome Variant ServerDECR2
ExAC (Exome Aggregation Consortium)ENSG00000242612
GNOMAD BrowserENSG00000242612
Genetic variants : HAPMAP26063
Genomic Variants (DGV)DECR2 [DGVbeta]
DECIPHERDECR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDECR2 
Mutations
ICGC Data PortalDECR2 
TCGA Data PortalDECR2 
Broad Tumor PortalDECR2
OASIS PortalDECR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDECR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDECR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DECR2
DgiDB (Drug Gene Interaction Database)DECR2
DoCM (Curated mutations)DECR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DECR2 (select a term)
intoGenDECR2
Cancer3DDECR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615839   
Orphanet
DisGeNETDECR2
MedgenDECR2
Genetic Testing Registry DECR2
NextProtQ9NUI1 [Medical]
TSGene26063
GENETestsDECR2
Target ValidationDECR2
Huge Navigator DECR2 [HugePedia]
snp3D : Map Gene to Disease26063
BioCentury BCIQDECR2
ClinGenDECR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD26063
Chemical/Pharm GKB GenePA27235
Clinical trialDECR2
Miscellaneous
canSAR (ICR)DECR2 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDECR2
EVEXDECR2
GoPubMedDECR2
iHOPDECR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:33:08 CET 2017

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