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DEF8 (differentially expressed in FDCP 8 homolog)

Identity

Alias_namesdifferentially expressed in FDCP 8 homolog (mouse)
Alias_symbol (synonym)FLJ20186
Other alias-
HGNC (Hugo) DEF8
LocusID (NCBI) 54849
Atlas_Id 62379
Location 16q24.3  [Link to chromosome band 16q24]
Location_base_pair Starts at 89948731 and ends at 89968060 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DEF8 (16q24.3) / APLP2 (11q24.3)DEF8 (16q24.3) / FBXO31 (16q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEF8   25969
Cards
Entrez_Gene (NCBI)DEF8  54849  differentially expressed in FDCP 8 homolog
Aliases
GeneCards (Weizmann)DEF8
Ensembl hg19 (Hinxton)ENSG00000140995 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140995 [Gene_View]  chr16:89948731-89968060 [Contig_View]  DEF8 [Vega]
ICGC DataPortalENSG00000140995
TCGA cBioPortalDEF8
AceView (NCBI)DEF8
Genatlas (Paris)DEF8
WikiGenes54849
SOURCE (Princeton)DEF8
Genetics Home Reference (NIH)DEF8
Genomic and cartography
GoldenPath hg38 (UCSC)DEF8  -     chr16:89948731-89968060 +  16q24.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEF8  -     16q24.3   [Description]    (hg19-Feb_2009)
EnsemblDEF8 - 16q24.3 [CytoView hg19]  DEF8 - 16q24.3 [CytoView hg38]
Mapping of homologs : NCBIDEF8 [Mapview hg19]  DEF8 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF289561 AK000193 AK055099 AK095051 AK096485
RefSeq transcript (Entrez)NM_001242816 NM_001242817 NM_001242818 NM_001242819 NM_001242820 NM_001242821 NM_001242822 NM_017702 NM_207514
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DEF8
Cluster EST : UnigeneHs.62771 [ NCBI ]
CGAP (NCI)Hs.62771
Alternative Splicing GalleryENSG00000140995
Gene ExpressionDEF8 [ NCBI-GEO ]   DEF8 [ EBI - ARRAY_EXPRESS ]   DEF8 [ SEEK ]   DEF8 [ MEM ]
Gene Expression Viewer (FireBrowse)DEF8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)54849
GTEX Portal (Tissue expression)DEF8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZN54   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZN54  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZN54
Splice isoforms : SwissVarQ6ZN54
PhosPhoSitePlusQ6ZN54
Domaine pattern : Prosite (Expaxy)ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)PE/DAG-bd    Zf-RING_9   
Domain families : Pfam (Sanger)C1_1 (PF00130)    zf-RING_9 (PF13901)   
Domain families : Pfam (NCBI)pfam00130    pfam13901   
Domain families : Smart (EMBL)C1 (SM00109)  DUF4206 (SM01175)  
Conserved Domain (NCBI)DEF8
DMDM Disease mutations54849
Blocks (Seattle)DEF8
SuperfamilyQ6ZN54
Human Protein AtlasENSG00000140995
Peptide AtlasQ6ZN54
HPRD07882
IPIIPI00410572   IPI00182859   IPI00885026   IPI00930505   IPI00930114   IPI00103805   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZN54
IntAct (EBI)Q6ZN54
FunCoupENSG00000140995
BioGRIDDEF8
STRING (EMBL)DEF8
ZODIACDEF8
Ontologies - Pathways
QuickGOQ6ZN54
Ontology : AmiGOintracellular  intracellular signal transduction  metal ion binding  
Ontology : EGO-EBIintracellular  intracellular signal transduction  metal ion binding  
NDEx NetworkDEF8
Atlas of Cancer Signalling NetworkDEF8
Wikipedia pathwaysDEF8
Orthology - Evolution
OrthoDB54849
GeneTree (enSembl)ENSG00000140995
Phylogenetic Trees/Animal Genes : TreeFamDEF8
HOVERGENQ6ZN54
HOGENOMQ6ZN54
Homologs : HomoloGeneDEF8
Homology/Alignments : Family Browser (UCSC)DEF8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEF8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEF8
dbVarDEF8
ClinVarDEF8
1000_GenomesDEF8 
Exome Variant ServerDEF8
ExAC (Exome Aggregation Consortium)DEF8 (select the gene name)
Genetic variants : HAPMAP54849
Genomic Variants (DGV)DEF8 [DGVbeta]
DECIPHERDEF8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEF8 
Mutations
ICGC Data PortalDEF8 
TCGA Data PortalDEF8 
Broad Tumor PortalDEF8
OASIS PortalDEF8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEF8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDEF8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEF8
DgiDB (Drug Gene Interaction Database)DEF8
DoCM (Curated mutations)DEF8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEF8 (select a term)
intoGenDEF8
Cancer3DDEF8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDEF8
Genetic Testing Registry DEF8
NextProtQ6ZN54 [Medical]
TSGene54849
GENETestsDEF8
Target ValidationDEF8
Huge Navigator DEF8 [HugePedia]
snp3D : Map Gene to Disease54849
BioCentury BCIQDEF8
ClinGenDEF8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD54849
Chemical/Pharm GKB GenePA162383526
Clinical trialDEF8
Miscellaneous
canSAR (ICR)DEF8 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEF8
EVEXDEF8
GoPubMedDEF8
iHOPDEF8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:45:32 CEST 2017

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