DEFA3 (defensin, alpha 3, neutrophil-specific)

Identity

Other names	DEF3
	HNP-3
	HNP3
	HP-3
HGNC	DEFA3
Location	8p23.1
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DEFA3   2762
Entrez_Gene	DEFA3  1668  defensin, alpha 3, neutrophil-specific
	Cards
GeneCards	DEFA3
Ensembl	DEFA3 [Search_View]   ENSG00000185918 [Gene_View]
Genatlas	DEFA3
GeneLynx	DEFA3
eGenome	DEFA3
euGene	1668
	Genomic and cartography
GoldenPath	DEFA3  -  8p23.1   chr8:6860805-6863226 -  8p23.1   [Description]    (hg18-March_2006)
Ensembl	DEFA3 - 8p23.1 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DEFA3
	Gene and transcription
Genbank	BC027917 [ ENTREZ ]
Genbank	BC119706 [ ENTREZ ]
Genbank	EU176174 [ ENTREZ ]
Genbank	M21131 [ ENTREZ ]
Genbank	M23281 [ ENTREZ ]
RefSeq	NM_005217 [ SRS ]    NM_005217 [ ENTREZ ]
RefSeq	AC_000140 [ SRS ]    AC_000140 [ ENTREZ ]
RefSeq	NC_000008 [ SRS ]    NC_000008 [ ENTREZ ]
RefSeq	NT_023736 [ SRS ]    NT_023736 [ ENTREZ ]
RefSeq	NW_001839109 [ SRS ]    NW_001839109 [ ENTREZ ]
AceView	DEFA3 AceView - NCBI
Unigene	Hs.654448 [ SRS ]    Hs.654448 [ NCBI ]     HS654448 [ spliceNest ]
Fast-db	1051 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	P59666 [ SRS]    P59666 [ EXPASY ]     P59666 [ INTERPRO ]     P59666 [ UNIPROT ]
Prosite	PS00269 DEFENSIN [ SRS ]    PS00269 DEFENSIN [ Expasy ]
Interpro	IPR016327 Alpha-defensin [ SRS ]    IPR016327 Alpha-defensin [ EBI ]
Interpro	IPR006081 Defensin_alpha [ SRS ]    IPR006081 Defensin_alpha [ EBI ]
Interpro	IPR006080 Defensin_mammal [ SRS ]    IPR006080 Defensin_mammal [ EBI ]
Interpro	IPR002366 Defensin_propep [ SRS ]    IPR002366 Defensin_propep [ EBI ]
CluSTr	P59666
Pfam	PF00323 Defensin_1 [ SRS ]    PF00323 Defensin_1 [ Sanger ]    pfam00323 [ NCBI-CDD ]
Pfam	PF00879 Defensin_propep [ SRS ]    PF00879 Defensin_propep [ Sanger ]    pfam00879 [ NCBI-CDD ]
Smart	SM00048 DEFSN [EMBL]
Blocks	P59666
PDB	1ZMH [ SRS ]    1ZMH [ PdbSum ],   1ZMH [ IMB ]   1ZMH [ RSDB ]
PDB	1ZMI [ SRS ]    1ZMI [ PdbSum ],   1ZMI [ IMB ]   1ZMI [ RSDB ]
PDB	1ZMK [ SRS ]    1ZMK [ PdbSum ],   1ZMK [ IMB ]   1ZMK [ RSDB ]
PDB	2PM4 [ SRS ]    2PM4 [ PdbSum ],   2PM4 [ IMB ]   2PM4 [ RSDB ]
PDB	2PM5 [ SRS ]    2PM5 [ PdbSum ],   2PM5 [ IMB ]   2PM5 [ RSDB ]
HPRD	05159
	Protein Interaction databases
DIP	P59666
IntAct	P59666
	Polymorphism : SNP, mutations, diseases
OMIM	604522    [ map ]
GENECLINICS	604522
SNP	DEFA3 [dbSNP-NCBI]
SNP	NM_005217 [SNP-NCI]
SNP	DEFA3 [GeneSNPs - Utah]  DEFA3] [HGBASE - SRS]
HAPMAP	DEFA3 [HAPMAP]
HGMD	DEFA3
	General knowledge
Family Browser	DEFA3 [UCSC Family Browser]
SOURCE	NM_005217
SMD	Hs.654448
SAGE	Hs.654448
GO	extracellular region [Amigo]  extracellular region
GO	xenobiotic metabolic process [Amigo]  xenobiotic metabolic process
GO	response to virus [Amigo]  response to virus
GO	defense response to bacterium [Amigo]  defense response to bacterium
GO	defense response to fungus [Amigo]  defense response to fungus
KEGG	Neuroactive ligand-receptor interaction
PubGene	DEFA3
TreeFam	DEFA3
CTD	1668 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DEFA3 Related clones (RZPD - Berlin)
	PubMed
PubMed	33 Pubmed reference(s) in LocusLink

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REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

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Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Mon Aug 11 20:07:42 2008