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DEFB104B (defensin beta 104B)

Identity

Alias_namesdefensin, beta 104B
Other aliasBD-4
DEFB-4
hBD-4
HGNC (Hugo) DEFB104B
LocusID (NCBI) 503618
Atlas_Id 62386
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 7470308 and ends at 7475082 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEFB104B   26165
Cards
Entrez_Gene (NCBI)DEFB104B  503618  defensin beta 104B
AliasesBD-4; DEFB-4; hBD-4
GeneCards (Weizmann)DEFB104B
Ensembl hg19 (Hinxton)ENSG00000177023 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000177023 [Gene_View]  chr8:7470308-7475082 [Contig_View]  DEFB104B [Vega]
ICGC DataPortalENSG00000177023
TCGA cBioPortalDEFB104B
AceView (NCBI)DEFB104B
Genatlas (Paris)DEFB104B
WikiGenes503618
SOURCE (Princeton)DEFB104B
Genetics Home Reference (NIH)DEFB104B
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB104B  -     chr8:7470308-7475082 -  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB104B  -     8p23.1   [Description]    (hg19-Feb_2009)
EnsemblDEFB104B - 8p23.1 [CytoView hg19]  DEFB104B - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBIDEFB104B [Mapview hg19]  DEFB104B [Mapview hg38]
Gene and transcription
Genbank (Entrez)AJ314834 BC100848 BC100849 BC100850 BC100851
RefSeq transcript (Entrez)NM_001040702
RefSeq genomic (Entrez)NC_000008 NT_187570
Consensus coding sequences : CCDS (NCBI)DEFB104B
Cluster EST : UnigeneHs.745562 [ NCBI ]
CGAP (NCI)Hs.745562
Alternative Splicing GalleryENSG00000177023
Gene ExpressionDEFB104B [ NCBI-GEO ]   DEFB104B [ EBI - ARRAY_EXPRESS ]   DEFB104B [ SEEK ]   DEFB104B [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB104B [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)503618
GTEX Portal (Tissue expression)DEFB104B
Human Protein AtlasENSG00000177023-DEFB104B [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8WTQ1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8WTQ1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8WTQ1
Splice isoforms : SwissVarQ8WTQ1
PhosPhoSitePlusQ8WTQ1
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)Defensin_beta_2 (PF13841)   
Domain families : Pfam (NCBI)pfam13841   
Conserved Domain (NCBI)DEFB104B
DMDM Disease mutations503618
Blocks (Seattle)DEFB104B
SuperfamilyQ8WTQ1
Human Protein Atlas [tissue]ENSG00000177023-DEFB104B [tissue]
Peptide AtlasQ8WTQ1
Protein Interaction databases
DIP (DOE-UCLA)Q8WTQ1
IntAct (EBI)Q8WTQ1
FunCoupENSG00000177023
BioGRIDDEFB104B
STRING (EMBL)DEFB104B
ZODIACDEFB104B
Ontologies - Pathways
QuickGOQ8WTQ1
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB104B
Atlas of Cancer Signalling NetworkDEFB104B
Wikipedia pathwaysDEFB104B
Orthology - Evolution
OrthoDB503618
GeneTree (enSembl)ENSG00000177023
Phylogenetic Trees/Animal Genes : TreeFamDEFB104B
HOVERGENQ8WTQ1
HOGENOMQ8WTQ1
Homologs : HomoloGeneDEFB104B
Homology/Alignments : Family Browser (UCSC)DEFB104B
Gene fusions - Rearrangements
Fusion: Tumor Portal DEFB104B
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB104B [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB104B
dbVarDEFB104B
ClinVarDEFB104B
1000_GenomesDEFB104B 
Exome Variant ServerDEFB104B
ExAC (Exome Aggregation Consortium)ENSG00000177023
GNOMAD BrowserENSG00000177023
Genetic variants : HAPMAP503618
Genomic Variants (DGV)DEFB104B [DGVbeta]
DECIPHERDEFB104B [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB104B 
Mutations
ICGC Data PortalDEFB104B 
TCGA Data PortalDEFB104B 
Broad Tumor PortalDEFB104B
OASIS PortalDEFB104B [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDDEFB104B
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB104B
DgiDB (Drug Gene Interaction Database)DEFB104B
DoCM (Curated mutations)DEFB104B (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB104B (select a term)
intoGenDEFB104B
Cancer3DDEFB104B(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDEFB104B
Genetic Testing Registry DEFB104B
NextProtQ8WTQ1 [Medical]
TSGene503618
GENETestsDEFB104B
Target ValidationDEFB104B
Huge Navigator DEFB104B [HugePedia]
snp3D : Map Gene to Disease503618
BioCentury BCIQDEFB104B
ClinGenDEFB104B
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD503618
Chemical/Pharm GKB GenePA142671990
Clinical trialDEFB104B
Miscellaneous
canSAR (ICR)DEFB104B (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB104B
EVEXDEFB104B
GoPubMedDEFB104B
iHOPDEFB104B
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:44:17 CET 2017

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