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DEFB105A (defensin beta 105A)

Identity

Alias_namesDEFB105
defensin, beta 105
defensin, beta 105A
Alias_symbol (synonym)DEFB-5
Other aliasBD-5
HGNC (Hugo) DEFB105A
LocusID (NCBI) 245908
Atlas_Id 62387
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 7487669 and ends at 7489593 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEFB105A   18087
Cards
Entrez_Gene (NCBI)DEFB105A  245908  defensin beta 105A
AliasesBD-5; DEFB-5; DEFB105
GeneCards (Weizmann)DEFB105A
Ensembl hg19 (Hinxton)ENSG00000186562 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000186562 [Gene_View]  chr8:7487669-7489593 [Contig_View]  DEFB105A [Vega]
ICGC DataPortalENSG00000186562
TCGA cBioPortalDEFB105A
AceView (NCBI)DEFB105A
Genatlas (Paris)DEFB105A
WikiGenes245908
SOURCE (Princeton)DEFB105A
Genetics Home Reference (NIH)DEFB105A
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB105A  -     chr8:7487669-7489593 +  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB105A  -     8p23.1   [Description]    (hg19-Feb_2009)
EnsemblDEFB105A - 8p23.1 [CytoView hg19]  DEFB105A - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBIDEFB105A [Mapview hg19]  DEFB105A [Mapview hg38]
Gene and transcription
Genbank (Entrez)AB089180 AF540977 BC128437 BC128438 BC140937
RefSeq transcript (Entrez)NM_152250
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DEFB105A
Cluster EST : UnigeneHs.381378 [ NCBI ]
CGAP (NCI)Hs.381378
Alternative Splicing GalleryENSG00000186562
Gene ExpressionDEFB105A [ NCBI-GEO ]   DEFB105A [ EBI - ARRAY_EXPRESS ]   DEFB105A [ SEEK ]   DEFB105A [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB105A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)245908
GTEX Portal (Tissue expression)DEFB105A
Human Protein AtlasENSG00000186562-DEFB105A [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NG35   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NG35  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NG35
Splice isoforms : SwissVarQ8NG35
PhosPhoSitePlusQ8NG35
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)Defensin_beta_2 (PF13841)   
Domain families : Pfam (NCBI)pfam13841   
Conserved Domain (NCBI)DEFB105A
DMDM Disease mutations245908
Blocks (Seattle)DEFB105A
SuperfamilyQ8NG35
Human Protein Atlas [tissue]ENSG00000186562-DEFB105A [tissue]
Peptide AtlasQ8NG35
HPRD10871
IPIIPI00168897   
Protein Interaction databases
DIP (DOE-UCLA)Q8NG35
IntAct (EBI)Q8NG35
FunCoupENSG00000186562
BioGRIDDEFB105A
STRING (EMBL)DEFB105A
ZODIACDEFB105A
Ontologies - Pathways
QuickGOQ8NG35
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB105A
Atlas of Cancer Signalling NetworkDEFB105A
Wikipedia pathwaysDEFB105A
Orthology - Evolution
OrthoDB245908
GeneTree (enSembl)ENSG00000186562
Phylogenetic Trees/Animal Genes : TreeFamDEFB105A
HOVERGENQ8NG35
HOGENOMQ8NG35
Homologs : HomoloGeneDEFB105A
Homology/Alignments : Family Browser (UCSC)DEFB105A
Gene fusions - Rearrangements
Fusion: Tumor Portal DEFB105A
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB105A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB105A
dbVarDEFB105A
ClinVarDEFB105A
1000_GenomesDEFB105A 
Exome Variant ServerDEFB105A
ExAC (Exome Aggregation Consortium)ENSG00000186562
GNOMAD BrowserENSG00000186562
Genetic variants : HAPMAP245908
Genomic Variants (DGV)DEFB105A [DGVbeta]
DECIPHERDEFB105A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB105A 
Mutations
ICGC Data PortalDEFB105A 
TCGA Data PortalDEFB105A 
Broad Tumor PortalDEFB105A
OASIS PortalDEFB105A [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEFB105A  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDEFB105A
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB105A
DgiDB (Drug Gene Interaction Database)DEFB105A
DoCM (Curated mutations)DEFB105A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB105A (select a term)
intoGenDEFB105A
Cancer3DDEFB105A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDEFB105A
Genetic Testing Registry DEFB105A
NextProtQ8NG35 [Medical]
TSGene245908
GENETestsDEFB105A
Target ValidationDEFB105A
Huge Navigator DEFB105A [HugePedia]
snp3D : Map Gene to Disease245908
BioCentury BCIQDEFB105A
ClinGenDEFB105A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD245908
Chemical/Pharm GKB GenePA38483
Clinical trialDEFB105A
Miscellaneous
canSAR (ICR)DEFB105A (select the gene name)
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB105A
EVEXDEFB105A
GoPubMedDEFB105A
iHOPDEFB105A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Nov 9 11:44:17 CET 2017

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