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DEFB115 (defensin beta 115)

Identity

Alias_namesdefensin, beta 115
Alias_symbol (synonym)DEFB-15
Other alias
HGNC (Hugo) DEFB115
LocusID (NCBI) 245929
Atlas_Id 62402
Location 20q11.21  [Link to chromosome band 20q11]
Location_base_pair Starts at 31257664 and ends at 31259632 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEFB115   18096
Cards
Entrez_Gene (NCBI)DEFB115  245929  defensin beta 115
AliasesDEFB-15
GeneCards (Weizmann)DEFB115
Ensembl hg19 (Hinxton)ENSG00000215547 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000215547 [Gene_View]  chr20:31257664-31259632 [Contig_View]  DEFB115 [Vega]
ICGC DataPortalENSG00000215547
TCGA cBioPortalDEFB115
AceView (NCBI)DEFB115
Genatlas (Paris)DEFB115
WikiGenes245929
SOURCE (Princeton)DEFB115
Genetics Home Reference (NIH)DEFB115
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB115  -     chr20:31257664-31259632 +  20q11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB115  -     20q11.21   [Description]    (hg19-Feb_2009)
EnsemblDEFB115 - 20q11.21 [CytoView hg19]  DEFB115 - 20q11.21 [CytoView hg38]
Mapping of homologs : NCBIDEFB115 [Mapview hg19]  DEFB115 [Mapview hg38]
Gene and transcription
Genbank (Entrez)BC152826 DQ012019
RefSeq transcript (Entrez)NM_001037730
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DEFB115
Cluster EST : UnigeneHs.580793 [ NCBI ]
CGAP (NCI)Hs.580793
Alternative Splicing GalleryENSG00000215547
Gene ExpressionDEFB115 [ NCBI-GEO ]   DEFB115 [ EBI - ARRAY_EXPRESS ]   DEFB115 [ SEEK ]   DEFB115 [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB115 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)245929
GTEX Portal (Tissue expression)DEFB115
Human Protein AtlasENSG00000215547-DEFB115 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ30KQ5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ30KQ5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ30KQ5
Splice isoforms : SwissVarQ30KQ5
PhosPhoSitePlusQ30KQ5
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)DEFB115
DMDM Disease mutations245929
Blocks (Seattle)DEFB115
SuperfamilyQ30KQ5
Human Protein Atlas [tissue]ENSG00000215547-DEFB115 [tissue]
Peptide AtlasQ30KQ5
IPIIPI00655628   
Protein Interaction databases
DIP (DOE-UCLA)Q30KQ5
IntAct (EBI)Q30KQ5
FunCoupENSG00000215547
BioGRIDDEFB115
STRING (EMBL)DEFB115
ZODIACDEFB115
Ontologies - Pathways
QuickGOQ30KQ5
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB115
Atlas of Cancer Signalling NetworkDEFB115
Wikipedia pathwaysDEFB115
Orthology - Evolution
OrthoDB245929
GeneTree (enSembl)ENSG00000215547
Phylogenetic Trees/Animal Genes : TreeFamDEFB115
HOVERGENQ30KQ5
HOGENOMQ30KQ5
Homologs : HomoloGeneDEFB115
Homology/Alignments : Family Browser (UCSC)DEFB115
Gene fusions - Rearrangements
Tumor Fusion PortalDEFB115
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB115 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB115
dbVarDEFB115
ClinVarDEFB115
1000_GenomesDEFB115 
Exome Variant ServerDEFB115
ExAC (Exome Aggregation Consortium)ENSG00000215547
GNOMAD BrowserENSG00000215547
Genetic variants : HAPMAP245929
Genomic Variants (DGV)DEFB115 [DGVbeta]
DECIPHERDEFB115 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB115 
Mutations
ICGC Data PortalDEFB115 
TCGA Data PortalDEFB115 
Broad Tumor PortalDEFB115
OASIS PortalDEFB115 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEFB115  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDEFB115
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB115
DgiDB (Drug Gene Interaction Database)DEFB115
DoCM (Curated mutations)DEFB115 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB115 (select a term)
intoGenDEFB115
Cancer3DDEFB115(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
DisGeNETDEFB115
MedgenDEFB115
Genetic Testing Registry DEFB115
NextProtQ30KQ5 [Medical]
TSGene245929
GENETestsDEFB115
Target ValidationDEFB115
Huge Navigator DEFB115 [HugePedia]
snp3D : Map Gene to Disease245929
BioCentury BCIQDEFB115
ClinGenDEFB115
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD245929
Chemical/Pharm GKB GenePA38492
Clinical trialDEFB115
Miscellaneous
canSAR (ICR)DEFB115 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB115
EVEXDEFB115
GoPubMedDEFB115
iHOPDEFB115
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 13:41:22 CET 2017

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