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DEFB125 (defensin beta 125)

Identity

Alias_namesdefensin, beta 125
Alias_symbol (synonym)DEFB-25
Other alias
HGNC (Hugo) DEFB125
LocusID (NCBI) 245938
Atlas_Id 62411
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 87672 and ends at 96573 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
TRIB3 (20p13) / DEFB125 (20p13)WASH1 (9p24.3) / DEFB125 (20p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEFB125   18105
Cards
Entrez_Gene (NCBI)DEFB125  245938  defensin beta 125
AliasesDEFB-25
GeneCards (Weizmann)DEFB125
Ensembl hg19 (Hinxton)ENSG00000178591 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000178591 [Gene_View]  chr20:87672-96573 [Contig_View]  DEFB125 [Vega]
ICGC DataPortalENSG00000178591
TCGA cBioPortalDEFB125
AceView (NCBI)DEFB125
Genatlas (Paris)DEFB125
WikiGenes245938
SOURCE (Princeton)DEFB125
Genetics Home Reference (NIH)DEFB125
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB125  -     chr20:87672-96573 +  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB125  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblDEFB125 - 20p13 [CytoView hg19]  DEFB125 - 20p13 [CytoView hg38]
Mapping of homologs : NCBIDEFB125 [Mapview hg19]  DEFB125 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA935636 AF525927 AK311802 AY122477 BC128195
RefSeq transcript (Entrez)NM_153325
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DEFB125
Cluster EST : UnigeneHs.380220 [ NCBI ]
CGAP (NCI)Hs.380220
Alternative Splicing GalleryENSG00000178591
Gene ExpressionDEFB125 [ NCBI-GEO ]   DEFB125 [ EBI - ARRAY_EXPRESS ]   DEFB125 [ SEEK ]   DEFB125 [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB125 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)245938
GTEX Portal (Tissue expression)DEFB125
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8N687   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8N687  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8N687
Splice isoforms : SwissVarQ8N687
PhosPhoSitePlusQ8N687
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)Defensin_beta_2 (PF13841)   
Domain families : Pfam (NCBI)pfam13841   
Domain structure : Prodom (Prabi Lyon)PD866254 (PD866254)   
Conserved Domain (NCBI)DEFB125
DMDM Disease mutations245938
Blocks (Seattle)DEFB125
SuperfamilyQ8N687
Human Protein AtlasENSG00000178591
Peptide AtlasQ8N687
IPIIPI00748187   
Protein Interaction databases
DIP (DOE-UCLA)Q8N687
IntAct (EBI)Q8N687
FunCoupENSG00000178591
BioGRIDDEFB125
STRING (EMBL)DEFB125
ZODIACDEFB125
Ontologies - Pathways
QuickGOQ8N687
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB125
Atlas of Cancer Signalling NetworkDEFB125
Wikipedia pathwaysDEFB125
Orthology - Evolution
OrthoDB245938
GeneTree (enSembl)ENSG00000178591
Phylogenetic Trees/Animal Genes : TreeFamDEFB125
HOVERGENQ8N687
HOGENOMQ8N687
Homologs : HomoloGeneDEFB125
Homology/Alignments : Family Browser (UCSC)DEFB125
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB125 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB125
dbVarDEFB125
ClinVarDEFB125
1000_GenomesDEFB125 
Exome Variant ServerDEFB125
ExAC (Exome Aggregation Consortium)DEFB125 (select the gene name)
Genetic variants : HAPMAP245938
Genomic Variants (DGV)DEFB125 [DGVbeta]
DECIPHERDEFB125 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB125 
Mutations
ICGC Data PortalDEFB125 
TCGA Data PortalDEFB125 
Broad Tumor PortalDEFB125
OASIS PortalDEFB125 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEFB125  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDEFB125
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB125
DgiDB (Drug Gene Interaction Database)DEFB125
DoCM (Curated mutations)DEFB125 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB125 (select a term)
intoGenDEFB125
Cancer3DDEFB125(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDEFB125
Genetic Testing Registry DEFB125
NextProtQ8N687 [Medical]
TSGene245938
GENETestsDEFB125
Target ValidationDEFB125
Huge Navigator DEFB125 [HugePedia]
snp3D : Map Gene to Disease245938
BioCentury BCIQDEFB125
ClinGenDEFB125
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD245938
Chemical/Pharm GKB GenePA38501
Clinical trialDEFB125
Miscellaneous
canSAR (ICR)DEFB125 (select the gene name)
Probes
Litterature
PubMed4 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB125
EVEXDEFB125
GoPubMedDEFB125
iHOPDEFB125
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:45:39 CEST 2017

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