Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DEFB128 (defensin beta 128)

Identity

Alias_namesdefensin, beta 128
Alias_symbol (synonym)DEFB-28
Other aliasDEFB28
hBD-28
HGNC (Hugo) DEFB128
LocusID (NCBI) 245939
Atlas_Id 62414
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 187853 and ends at 189681 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEFB128   18106
Cards
Entrez_Gene (NCBI)DEFB128  245939  defensin beta 128
AliasesDEFB-28; DEFB28; hBD-28
GeneCards (Weizmann)DEFB128
Ensembl hg19 (Hinxton)ENSG00000185982 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185982 [Gene_View]  chr20:187853-189681 [Contig_View]  DEFB128 [Vega]
ICGC DataPortalENSG00000185982
TCGA cBioPortalDEFB128
AceView (NCBI)DEFB128
Genatlas (Paris)DEFB128
WikiGenes245939
SOURCE (Princeton)DEFB128
Genetics Home Reference (NIH)DEFB128
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB128  -     chr20:187853-189681 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB128  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblDEFB128 - 20p13 [CytoView hg19]  DEFB128 - 20p13 [CytoView hg38]
Mapping of homologs : NCBIDEFB128 [Mapview hg19]  DEFB128 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF525930 BC140936
RefSeq transcript (Entrez)NM_001037732
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DEFB128
Cluster EST : UnigeneHs.516818 [ NCBI ]
CGAP (NCI)Hs.516818
Alternative Splicing GalleryENSG00000185982
Gene ExpressionDEFB128 [ NCBI-GEO ]   DEFB128 [ EBI - ARRAY_EXPRESS ]   DEFB128 [ SEEK ]   DEFB128 [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB128 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)245939
GTEX Portal (Tissue expression)DEFB128
Human Protein AtlasENSG00000185982-DEFB128 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z7B8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z7B8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z7B8
Splice isoforms : SwissVarQ7Z7B8
PhosPhoSitePlusQ7Z7B8
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)Defensin_beta_2 (PF13841)   
Domain families : Pfam (NCBI)pfam13841   
Domain structure : Prodom (Prabi Lyon)PD866254 (PD866254)   
Conserved Domain (NCBI)DEFB128
DMDM Disease mutations245939
Blocks (Seattle)DEFB128
SuperfamilyQ7Z7B8
Human Protein Atlas [tissue]ENSG00000185982-DEFB128 [tissue]
Peptide AtlasQ7Z7B8
IPIIPI00385523   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z7B8
IntAct (EBI)Q7Z7B8
FunCoupENSG00000185982
BioGRIDDEFB128
STRING (EMBL)DEFB128
ZODIACDEFB128
Ontologies - Pathways
QuickGOQ7Z7B8
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB128
Atlas of Cancer Signalling NetworkDEFB128
Wikipedia pathwaysDEFB128
Orthology - Evolution
OrthoDB245939
GeneTree (enSembl)ENSG00000185982
Phylogenetic Trees/Animal Genes : TreeFamDEFB128
HOVERGENQ7Z7B8
HOGENOMQ7Z7B8
Homologs : HomoloGeneDEFB128
Homology/Alignments : Family Browser (UCSC)DEFB128
Gene fusions - Rearrangements
Fusion: Tumor Portal DEFB128
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB128 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB128
dbVarDEFB128
ClinVarDEFB128
1000_GenomesDEFB128 
Exome Variant ServerDEFB128
ExAC (Exome Aggregation Consortium)ENSG00000185982
GNOMAD BrowserENSG00000185982
Genetic variants : HAPMAP245939
Genomic Variants (DGV)DEFB128 [DGVbeta]
DECIPHERDEFB128 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB128 
Mutations
ICGC Data PortalDEFB128 
TCGA Data PortalDEFB128 
Broad Tumor PortalDEFB128
OASIS PortalDEFB128 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEFB128  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDEFB128
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB128
DgiDB (Drug Gene Interaction Database)DEFB128
DoCM (Curated mutations)DEFB128 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB128 (select a term)
intoGenDEFB128
Cancer3DDEFB128(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDEFB128
Genetic Testing Registry DEFB128
NextProtQ7Z7B8 [Medical]
TSGene245939
GENETestsDEFB128
Target ValidationDEFB128
Huge Navigator DEFB128 [HugePedia]
snp3D : Map Gene to Disease245939
BioCentury BCIQDEFB128
ClinGenDEFB128
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD245939
Chemical/Pharm GKB GenePA38502
Clinical trialDEFB128
Miscellaneous
canSAR (ICR)DEFB128 (select the gene name)
Probes
Litterature
PubMed5 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB128
EVEXDEFB128
GoPubMedDEFB128
iHOPDEFB128
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 11:44:23 CET 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.