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DEFB135 (defensin beta 135)

Identity

Alias_namesdefensin, beta 135
Other aliasDEFB136
HGNC (Hugo) DEFB135
LocusID (NCBI) 613209
Atlas_Id 62421
Location 8p23.1  [Link to chromosome band 8p23]
Location_base_pair Starts at 11982321 and ends at 11984590 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
MSRA (8p23.1) / DEFB135 (8p23.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DEFB135   32400
Cards
Entrez_Gene (NCBI)DEFB135  613209  defensin beta 135
AliasesDEFB136
GeneCards (Weizmann)DEFB135
Ensembl hg19 (Hinxton)ENSG00000205883 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000205883 [Gene_View]  chr8:11982321-11984590 [Contig_View]  DEFB135 [Vega]
ICGC DataPortalENSG00000205883
TCGA cBioPortalDEFB135
AceView (NCBI)DEFB135
Genatlas (Paris)DEFB135
WikiGenes613209
SOURCE (Princeton)DEFB135
Genetics Home Reference (NIH)DEFB135
Genomic and cartography
GoldenPath hg38 (UCSC)DEFB135  -     chr8:11982321-11984590 +  8p23.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DEFB135  -     8p23.1   [Description]    (hg19-Feb_2009)
EnsemblDEFB135 - 8p23.1 [CytoView hg19]  DEFB135 - 8p23.1 [CytoView hg38]
Mapping of homologs : NCBIDEFB135 [Mapview hg19]  DEFB135 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AY621332 BC140266 BC146563 DQ012025
RefSeq transcript (Entrez)NM_001033017
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DEFB135
Cluster EST : UnigeneHs.558284 [ NCBI ]
CGAP (NCI)Hs.558284
Alternative Splicing GalleryENSG00000205883
Gene ExpressionDEFB135 [ NCBI-GEO ]   DEFB135 [ EBI - ARRAY_EXPRESS ]   DEFB135 [ SEEK ]   DEFB135 [ MEM ]
Gene Expression Viewer (FireBrowse)DEFB135 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)613209
GTEX Portal (Tissue expression)DEFB135
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ30KP9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ30KP9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ30KP9
Splice isoforms : SwissVarQ30KP9
PhosPhoSitePlusQ30KP9
Domains : Interpro (EBI)Beta_defensin   
Domain families : Pfam (Sanger)Defensin_beta_2 (PF13841)   
Domain families : Pfam (NCBI)pfam13841   
Domain structure : Prodom (Prabi Lyon)PD866254 (PD866254)   
Conserved Domain (NCBI)DEFB135
DMDM Disease mutations613209
Blocks (Seattle)DEFB135
SuperfamilyQ30KP9
Human Protein AtlasENSG00000205883
Peptide AtlasQ30KP9
IPIIPI00607838   
Protein Interaction databases
DIP (DOE-UCLA)Q30KP9
IntAct (EBI)Q30KP9
FunCoupENSG00000205883
BioGRIDDEFB135
STRING (EMBL)DEFB135
ZODIACDEFB135
Ontologies - Pathways
QuickGOQ30KP9
Ontology : AmiGOextracellular region  defense response to bacterium  innate immune response  
Ontology : EGO-EBIextracellular region  defense response to bacterium  innate immune response  
NDEx NetworkDEFB135
Atlas of Cancer Signalling NetworkDEFB135
Wikipedia pathwaysDEFB135
Orthology - Evolution
OrthoDB613209
GeneTree (enSembl)ENSG00000205883
Phylogenetic Trees/Animal Genes : TreeFamDEFB135
HOVERGENQ30KP9
HOGENOMQ30KP9
Homologs : HomoloGeneDEFB135
Homology/Alignments : Family Browser (UCSC)DEFB135
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDEFB135 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DEFB135
dbVarDEFB135
ClinVarDEFB135
1000_GenomesDEFB135 
Exome Variant ServerDEFB135
ExAC (Exome Aggregation Consortium)DEFB135 (select the gene name)
Genetic variants : HAPMAP613209
Genomic Variants (DGV)DEFB135 [DGVbeta]
DECIPHERDEFB135 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDEFB135 
Mutations
ICGC Data PortalDEFB135 
TCGA Data PortalDEFB135 
Broad Tumor PortalDEFB135
OASIS PortalDEFB135 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDEFB135  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDEFB135
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DEFB135
DgiDB (Drug Gene Interaction Database)DEFB135
DoCM (Curated mutations)DEFB135 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DEFB135 (select a term)
intoGenDEFB135
Cancer3DDEFB135(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDEFB135
Genetic Testing Registry DEFB135
NextProtQ30KP9 [Medical]
TSGene613209
GENETestsDEFB135
Target ValidationDEFB135
Huge Navigator DEFB135 [HugePedia]
snp3D : Map Gene to Disease613209
BioCentury BCIQDEFB135
ClinGenDEFB135
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD613209
Chemical/Pharm GKB GenePA165585476
Clinical trialDEFB135
Miscellaneous
canSAR (ICR)DEFB135 (select the gene name)
Probes
Litterature
PubMed2 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDEFB135
EVEXDEFB135
GoPubMedDEFB135
iHOPDEFB135
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:45:42 CEST 2017

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