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DENND2D (DENN domain containing 2D)

Identity

Alias_namesDENN/MADD domain containing 2D
Alias_symbol (synonym)FLJ22457
RP5-1180E21.2
Other alias-
HGNC (Hugo) DENND2D
LocusID (NCBI) 79961
Atlas_Id 46828
Location 1p13.3  [Link to chromosome band 1p13]
Location_base_pair Starts at 111185969 and ends at 111204538 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AHCYL1 (1p13.3) / DENND2D (1p13.3)DENND2D (1p13.3) / DENND2D (1p13.3)AHCYL1 1p13.3 / DENND2D 1p13.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DENND2D   26192
Cards
Entrez_Gene (NCBI)DENND2D  79961  DENN domain containing 2D
Aliases
GeneCards (Weizmann)DENND2D
Ensembl hg19 (Hinxton)ENSG00000162777 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162777 [Gene_View]  chr1:111185969-111204538 [Contig_View]  DENND2D [Vega]
ICGC DataPortalENSG00000162777
TCGA cBioPortalDENND2D
AceView (NCBI)DENND2D
Genatlas (Paris)DENND2D
WikiGenes79961
SOURCE (Princeton)DENND2D
Genetics Home Reference (NIH)DENND2D
Genomic and cartography
GoldenPath hg38 (UCSC)DENND2D  -     chr1:111185969-111204538 -  1p13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DENND2D  -     1p13.3   [Description]    (hg19-Feb_2009)
EnsemblDENND2D - 1p13.3 [CytoView hg19]  DENND2D - 1p13.3 [CytoView hg38]
Mapping of homologs : NCBIDENND2D [Mapview hg19]  DENND2D [Mapview hg38]
OMIM615111   
Gene and transcription
Genbank (Entrez)AK026110 AK057181 AK301583 AL713773 BC004557
RefSeq transcript (Entrez)NM_001271833 NM_024901
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DENND2D
Cluster EST : UnigeneHs.557850 [ NCBI ]
CGAP (NCI)Hs.557850
Alternative Splicing GalleryENSG00000162777
Gene ExpressionDENND2D [ NCBI-GEO ]   DENND2D [ EBI - ARRAY_EXPRESS ]   DENND2D [ SEEK ]   DENND2D [ MEM ]
Gene Expression Viewer (FireBrowse)DENND2D [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)79961
GTEX Portal (Tissue expression)DENND2D
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H6A0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9H6A0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9H6A0
Splice isoforms : SwissVarQ9H6A0
PhosPhoSitePlusQ9H6A0
Domaine pattern : Prosite (Expaxy)DDENN (PS50947)    DENN (PS50211)    UDENN (PS50946)   
Domains : Interpro (EBI)dDENN_dom    DENN_dom    uDENN_dom   
Domain families : Pfam (Sanger)dDENN (PF03455)    DENN (PF02141)    uDENN (PF03456)   
Domain families : Pfam (NCBI)pfam03455    pfam02141    pfam03456   
Domain families : Smart (EMBL)dDENN (SM00801)  DENN (SM00799)  uDENN (SM00800)  
Conserved Domain (NCBI)DENND2D
DMDM Disease mutations79961
Blocks (Seattle)DENND2D
SuperfamilyQ9H6A0
Human Protein AtlasENSG00000162777
Peptide AtlasQ9H6A0
HPRD08655
IPIIPI00641666   IPI00165037   
Protein Interaction databases
DIP (DOE-UCLA)Q9H6A0
IntAct (EBI)Q9H6A0
FunCoupENSG00000162777
BioGRIDDENND2D
STRING (EMBL)DENND2D
ZODIACDENND2D
Ontologies - Pathways
QuickGOQ9H6A0
Ontology : AmiGOprotein binding  nucleoplasm  cytosol  Rab guanyl-nucleotide exchange factor activity  positive regulation of GTPase activity  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytosol  Rab guanyl-nucleotide exchange factor activity  positive regulation of GTPase activity  
NDEx NetworkDENND2D
Atlas of Cancer Signalling NetworkDENND2D
Wikipedia pathwaysDENND2D
Orthology - Evolution
OrthoDB79961
GeneTree (enSembl)ENSG00000162777
Phylogenetic Trees/Animal Genes : TreeFamDENND2D
HOVERGENQ9H6A0
HOGENOMQ9H6A0
Homologs : HomoloGeneDENND2D
Homology/Alignments : Family Browser (UCSC)DENND2D
Gene fusions - Rearrangements
Fusion : MitelmanAHCYL1/DENND2D [1p13.3/1p13.3]  [t(1;1)(p13;p13)]  
Fusion: TCGAAHCYL1 1p13.3 DENND2D 1p13.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDENND2D [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DENND2D
dbVarDENND2D
ClinVarDENND2D
1000_GenomesDENND2D 
Exome Variant ServerDENND2D
ExAC (Exome Aggregation Consortium)DENND2D (select the gene name)
Genetic variants : HAPMAP79961
Genomic Variants (DGV)DENND2D [DGVbeta]
DECIPHERDENND2D [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDENND2D 
Mutations
ICGC Data PortalDENND2D 
TCGA Data PortalDENND2D 
Broad Tumor PortalDENND2D
OASIS PortalDENND2D [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDENND2D  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDENND2D
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DENND2D
DgiDB (Drug Gene Interaction Database)DENND2D
DoCM (Curated mutations)DENND2D (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DENND2D (select a term)
intoGenDENND2D
Cancer3DDENND2D(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615111   
Orphanet
MedgenDENND2D
Genetic Testing Registry DENND2D
NextProtQ9H6A0 [Medical]
TSGene79961
GENETestsDENND2D
Huge Navigator DENND2D [HugePedia]
snp3D : Map Gene to Disease79961
BioCentury BCIQDENND2D
ClinGenDENND2D
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD79961
Chemical/Pharm GKB GenePA142671986
Clinical trialDENND2D
Miscellaneous
canSAR (ICR)DENND2D (select the gene name)
Probes
Litterature
PubMed16 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDENND2D
EVEXDENND2D
GoPubMedDENND2D
iHOPDENND2D
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:13:06 CEST 2017

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