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DENND4A (DENN/MADD domain containing 4A)

Identity

Other namesIRLB
MYCPBP
HGNC (Hugo) DENND4A
LocusID (NCBI) 10260
Location 15q22.31
Location_base_pair Starts at 65952957 and ends at 66084631 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)DENND4A   24321
Entrez_Gene (NCBI)DENND4A  10260  DENN/MADD domain containing 4A
Cards
GeneCards (Weizmann)DENND4A
Ensembl (Hinxton)ENSG00000174485 [Gene_View]  chr15:65952957-66084631 [Contig_View]  DENND4A [Vega]
AceView (NCBI)DENND4A
Genatlas (Paris)DENND4A
SOURCE (Stanford)NM_001144823 NM_005848
Genomic and cartography
GoldenPath (UCSC)DENND4A  -  15q22.31   chr15:65952957-66084631 -  15q22.31   [Description]    (hg19-Feb_2009)
EnsemblDENND4A - 15q22.31 [CytoView]
Mapping of homologs : NCBIDENND4A [Mapview]
OMIM600382   
Gene and transcription
Genbank (Entrez)AF534403 AK091268 AK091368 AK290292 AK299570
RefSeq transcript (SRS)NM_001144823 NM_005848
RefSeq transcript (Entrez)NM_001144823 NM_005848
RefSeq genomic (SRS)AC_000147 NC_000015 NC_018926 NT_010194 NW_001838218 NW_004078084
RefSeq genomic (Entrez)AC_000147 NC_000015 NC_018926 NT_010194 NW_001838218 NW_004078084
Consensus coding sequences : CCDS (NCBI)DENND4A
Cluster EST : UnigeneHs.654567 [ SRS ] Hs.654567 [ NCBI ]
CGAP (NCI)Hs.654567
Alternative Splicing : Fast-db (Paris)GSHG0010525
Alternative Splicing GalleryENSG00000174485
Gene ExpressionDENND4A [ NCBI-GEO ]   DENND4A [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z401 (SRS) Q7Z401 (Uniprot)
NextProtQ7Z401
With graphics : InterProQ7Z401
Splice isoforms : SwissVarQ7Z401(Swissvar)
Domaine pattern : Prosite (SRS)DDENN (PS50947)    DENN (PS50211)    MABP (PS51498)    PPR (PS51375)    UDENN (PS50946)   
Domaine pattern : Prosite (Expaxy)DDENN (PS50947)    DENN (PS50211)    MABP (PS51498)    PPR (PS51375)    UDENN (PS50946)   
Domains : Interpro (SRS)dDENN_dom    DENN_dom    MABP    Pentatricopeptide_repeat    uDENN_dom   
Domains : Interpro (EBI)dDENN_dom    DENN_dom    MABP    Pentatricopeptide_repeat    uDENN_dom   
Related proteins : CluSTrQ7Z401
Domain families : Pfam (SRS)dDENN (PF03455)    DENN (PF02141)    uDENN (PF03456)   
Domain families : Pfam (Sanger)dDENN (PF03455)    DENN (PF02141)    uDENN (PF03456)   
Domain families : Pfam (NCBI)pfam03455    pfam02141    pfam03456   
Domain families : Smart (EMBL)dDENN (SM00801)  DENN (SM00799)  uDENN (SM00800)  
DMDM10260
Blocks (Seattle)Q7Z401
Human Protein AtlasENSG00000174485
HPRD02662
IPIIPI00396063   IPI01009374   IPI00921122   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z401
IntAct (EBI)Q7Z401
FunCoupENSG00000174485
REACTOMEDENND4A
Protein Interaction Database10260
BioGRIDDENND4A
InParanoidQ7Z401
Interologous Interaction database Q7Z401
IntegromeDBDENND4A
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)DENND4A
SNP (GeneSNP Utah)DENND4A
SNP : HGBaseDENND4A
Genetic variants : HAPMAPDENND4A
Somatic Mutations in Cancer : COSMICDENND4A 
CONAN: Copy Number AnalysisDENND4A 
Mutations and Diseases : HGMDDENND4A
OMIM600382   
GENETests600382   
Disease Genetic AssociationDENND4A
Huge Navigator DENND4A [HugePedia]  DENND4A [HugeCancerGEM]
Genomic VariantsDENND4A  DENND4A [DGVbeta]
snp3D : Map Gene to Disease10260
General knowledge
Homologs : HomoloGeneDENND4A
Homology/Alignments : Family Browser (UCSC)DENND4A
Phylogenetic Trees/Animal Genes : TreeFamDENND4A
Chemical/Protein Interactions : CTD10260
Chemical/Pharm GKB GenePA134887513
Clinical trialDENND4A
Cancer Resource (Charite)ENSG00000174485
Ontology : AmiGODNA binding  nucleus  transcription, DNA-dependent  regulation of transcription, DNA-dependent  Rab guanyl-nucleotide exchange factor activity  
Ontology : EGO-EBIDNA binding  nucleus  transcription, DNA-dependent  regulation of transcription, DNA-dependent  Rab guanyl-nucleotide exchange factor activity  
Other databases
Probes
Litterature
PubMed12 Pubmed reference(s) in Entrez
PubGeneDENND4A
iHOPDENND4A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:37:08 CEST 2013
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