DENND4C (DENN domain containing 4C)

2011-08-01  

Identity

HGNC
LOCATION
9p22.1
LOCUSID
ALIAS
C9orf55,C9orf55B,RAB10GEF,bA513M16.3
FUSION GENES

Other Information

Locus ID:

NCBI: 55667
HGNC: 26079
Ensembl: ENSG00000137145

Variants:

dbSNP: 55667
ClinVar: 55667
TCGA: ENSG00000137145
COSMIC: DENND4C

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137145ENST00000361024X6R5W5
ENSG00000137145ENST00000380424A0A0A0MRX3
ENSG00000137145ENST00000380427X6RAE7
ENSG00000137145ENST00000434457Q5VZ89
ENSG00000137145ENST00000494124R4GMN2
ENSG00000137145ENST00000602925Q5VZ89

Expression (GTEx)

0
5
10
15
20
25
30

Pathways

PathwaySourceExternal ID
Vesicle-mediated transportREACTOMER-HSA-5653656
Membrane TraffickingREACTOMER-HSA-199991
RAB GEFs exchange GTP for GDP on RABsREACTOMER-HSA-8876198

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
214546972011Insulin-stimulated GLUT4 protein translocation in adipocytes requires the Rab10 guanine nucleotide exchange factor Dennd4C.29
314881932019Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia.10

Citation

Dessen P

DENND4C (DENN domain containing 4C)

Atlas Genet Cytogenet Oncol Haematol. 2011-08-01

Online version: http://atlasgeneticsoncology.org/gene/52357/dennd4c