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DENND6A (DENN domain containing 6A)

Identity

Alias_namesFAM116A
family with sequence similarity 116, member A
DENN/MADD domain containing 6A
Alias_symbol (synonym)FLJ34969
AFI1A
Other alias
HGNC (Hugo) DENND6A
LocusID (NCBI) 201627
Atlas_Id 62435
Location 3p14.3  [Link to chromosome band 3p14]
Location_base_pair Starts at 57625454 and ends at 57693089 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DENND6A   26635
Cards
Entrez_Gene (NCBI)DENND6A  201627  DENN domain containing 6A
AliasesAFI1A; FAM116A
GeneCards (Weizmann)DENND6A
Ensembl hg19 (Hinxton)ENSG00000174839 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000174839 [Gene_View]  chr3:57625454-57693089 [Contig_View]  DENND6A [Vega]
ICGC DataPortalENSG00000174839
TCGA cBioPortalDENND6A
AceView (NCBI)DENND6A
Genatlas (Paris)DENND6A
WikiGenes201627
SOURCE (Princeton)DENND6A
Genetics Home Reference (NIH)DENND6A
Genomic and cartography
GoldenPath hg38 (UCSC)DENND6A  -     chr3:57625454-57693089 -  3p14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DENND6A  -     3p14.3   [Description]    (hg19-Feb_2009)
EnsemblDENND6A - 3p14.3 [CytoView hg19]  DENND6A - 3p14.3 [CytoView hg38]
Mapping of homologs : NCBIDENND6A [Mapview hg19]  DENND6A [Mapview hg38]
Gene and transcription
Genbank (Entrez)AA605125 AK074156 AK092288 BC040291 BC054343
RefSeq transcript (Entrez)NM_152678
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DENND6A
Cluster EST : UnigeneHs.91085 [ NCBI ]
CGAP (NCI)Hs.91085
Alternative Splicing GalleryENSG00000174839
Gene ExpressionDENND6A [ NCBI-GEO ]   DENND6A [ EBI - ARRAY_EXPRESS ]   DENND6A [ SEEK ]   DENND6A [ MEM ]
Gene Expression Viewer (FireBrowse)DENND6A [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)201627
GTEX Portal (Tissue expression)DENND6A
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8IWF6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8IWF6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8IWF6
Splice isoforms : SwissVarQ8IWF6
PhosPhoSitePlusQ8IWF6
Domains : Interpro (EBI)ABL9/DENND6_dom    DENND6   
Domain families : Pfam (Sanger)Avl9 (PF09794)   
Domain families : Pfam (NCBI)pfam09794   
Conserved Domain (NCBI)DENND6A
DMDM Disease mutations201627
Blocks (Seattle)DENND6A
SuperfamilyQ8IWF6
Human Protein AtlasENSG00000174839
Peptide AtlasQ8IWF6
HPRD08756
IPIIPI00291723   IPI00946285   IPI00947164   
Protein Interaction databases
DIP (DOE-UCLA)Q8IWF6
IntAct (EBI)Q8IWF6
FunCoupENSG00000174839
BioGRIDDENND6A
STRING (EMBL)DENND6A
ZODIACDENND6A
Ontologies - Pathways
QuickGOQ8IWF6
Ontology : AmiGOcytoplasm  cytosol  Rab guanyl-nucleotide exchange factor activity  Rab guanyl-nucleotide exchange factor activity  intracellular membrane-bounded organelle  positive regulation of GTPase activity  recycling endosome  membrane organization  positive regulation of cell-cell adhesion mediated by cadherin  
Ontology : EGO-EBIcytoplasm  cytosol  Rab guanyl-nucleotide exchange factor activity  Rab guanyl-nucleotide exchange factor activity  intracellular membrane-bounded organelle  positive regulation of GTPase activity  recycling endosome  membrane organization  positive regulation of cell-cell adhesion mediated by cadherin  
NDEx NetworkDENND6A
Atlas of Cancer Signalling NetworkDENND6A
Wikipedia pathwaysDENND6A
Orthology - Evolution
OrthoDB201627
GeneTree (enSembl)ENSG00000174839
Phylogenetic Trees/Animal Genes : TreeFamDENND6A
HOVERGENQ8IWF6
HOGENOMQ8IWF6
Homologs : HomoloGeneDENND6A
Homology/Alignments : Family Browser (UCSC)DENND6A
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDENND6A [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DENND6A
dbVarDENND6A
ClinVarDENND6A
1000_GenomesDENND6A 
Exome Variant ServerDENND6A
ExAC (Exome Aggregation Consortium)DENND6A (select the gene name)
Genetic variants : HAPMAP201627
Genomic Variants (DGV)DENND6A [DGVbeta]
DECIPHERDENND6A [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDENND6A 
Mutations
ICGC Data PortalDENND6A 
TCGA Data PortalDENND6A 
Broad Tumor PortalDENND6A
OASIS PortalDENND6A [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDDENND6A
BioMutasearch DENND6A
DgiDB (Drug Gene Interaction Database)DENND6A
DoCM (Curated mutations)DENND6A (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DENND6A (select a term)
intoGenDENND6A
Cancer3DDENND6A(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenDENND6A
Genetic Testing Registry DENND6A
NextProtQ8IWF6 [Medical]
TSGene201627
GENETestsDENND6A
Target ValidationDENND6A
Huge Navigator DENND6A [HugePedia]
snp3D : Map Gene to Disease201627
BioCentury BCIQDENND6A
ClinGenDENND6A
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD201627
Chemical/Pharm GKB GenePA144596431
Clinical trialDENND6A
Miscellaneous
canSAR (ICR)DENND6A (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDENND6A
EVEXDENND6A
GoPubMedDENND6A
iHOPDENND6A
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:45:44 CEST 2017

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