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DFFB (DNA fragmentation factor subunit beta)

Identity

Alias_namesDNA fragmentation factor
Alias_symbol (synonym)CAD
CPAN
DFF-40
DFF40
Other aliasDFF2
HGNC (Hugo) DFFB
LocusID (NCBI) 1677
Atlas_Id 40298
Location 1p36.32  [Link to chromosome band 1p36]
Location_base_pair Starts at 3773831 and ends at 3801993 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DFFB   2773
Cards
Entrez_Gene (NCBI)DFFB  1677  DNA fragmentation factor subunit beta
AliasesCAD; CPAN; DFF-40; DFF2; 
DFF40
GeneCards (Weizmann)DFFB
Ensembl hg19 (Hinxton)ENSG00000169598 [Gene_View]  chr1:3773831-3801993 [Contig_View]  DFFB [Vega]
Ensembl hg38 (Hinxton)ENSG00000169598 [Gene_View]  chr1:3773831-3801993 [Contig_View]  DFFB [Vega]
ICGC DataPortalENSG00000169598
TCGA cBioPortalDFFB
AceView (NCBI)DFFB
Genatlas (Paris)DFFB
WikiGenes1677
SOURCE (Princeton)DFFB
Genetics Home Reference (NIH)DFFB
Genomic and cartography
GoldenPath hg19 (UCSC)DFFB  -     chr1:3773831-3801993 +  1p36.32   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DFFB  -     1p36.32   [Description]    (hg38-Dec_2013)
EnsemblDFFB - 1p36.32 [CytoView hg19]  DFFB - 1p36.32 [CytoView hg38]
Mapping of homologs : NCBIDFFB [Mapview hg19]  DFFB [Mapview hg38]
OMIM601883   
Gene and transcription
Genbank (Entrez)AB013918 AB028911 AB028912 AB028913 AF039210
RefSeq transcript (Entrez)NM_001004285 NM_001004286 NM_001282669 NM_001320132 NM_001320136 NM_004402
RefSeq genomic (Entrez)NC_000001 NC_018912 NT_032977 NW_004929288
Consensus coding sequences : CCDS (NCBI)DFFB
Cluster EST : UnigeneHs.133089 [ NCBI ]
CGAP (NCI)Hs.133089
Alternative Splicing GalleryENSG00000169598
Gene ExpressionDFFB [ NCBI-GEO ]   DFFB [ EBI - ARRAY_EXPRESS ]   DFFB [ SEEK ]   DFFB [ MEM ]
Gene Expression Viewer (FireBrowse)DFFB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1677
GTEX Portal (Tissue expression)DFFB
Protein : pattern, domain, 3D structure
UniProt/SwissProtO76075   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO76075  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO76075
Splice isoforms : SwissVarO76075
Catalytic activity : Enzyme3.-.-.- [ Enzyme-Expasy ]   3.-.-.-3.-.-.- [ IntEnz-EBI ]   3.-.-.- [ BRENDA ]   3.-.-.- [ KEGG ]   
PhosPhoSitePlusO76075
Domaine pattern : Prosite (Expaxy)CIDE_N (PS51135)   
Domains : Interpro (EBI)Apoptosis_DFF40    CIDE-N_dom   
Domain families : Pfam (Sanger)CIDE-N (PF02017)    DFF40 (PF09230)   
Domain families : Pfam (NCBI)pfam02017    pfam09230   
Conserved Domain (NCBI)DFFB
DMDM Disease mutations1677
Blocks (Seattle)DFFB
PDB (SRS)1IBX   
PDB (PDBSum)1IBX   
PDB (IMB)1IBX   
PDB (RSDB)1IBX   
Structural Biology KnowledgeBase1IBX   
SCOP (Structural Classification of Proteins)1IBX   
CATH (Classification of proteins structures)1IBX   
SuperfamilyO76075
Human Protein AtlasENSG00000169598
Peptide AtlasO76075
HPRD03532
IPIIPI00008794   IPI00179341   IPI00218518   IPI00883793   IPI00513824   IPI00791501   IPI01011650   
Protein Interaction databases
DIP (DOE-UCLA)O76075
IntAct (EBI)O76075
FunCoupENSG00000169598
BioGRIDDFFB
STRING (EMBL)DFFB
ZODIACDFFB
Ontologies - Pathways
QuickGOO76075
Ontology : AmiGOnuclear chromatin  deoxyribonuclease activity  nucleus  nucleoplasm  nucleolus  cytosol  cytosol  apoptotic DNA fragmentation  apoptotic DNA fragmentation  enzyme binding  apoptotic chromosome condensation  
Ontology : EGO-EBInuclear chromatin  deoxyribonuclease activity  nucleus  nucleoplasm  nucleolus  cytosol  cytosol  apoptotic DNA fragmentation  apoptotic DNA fragmentation  enzyme binding  apoptotic chromosome condensation  
Pathways : BIOCARTAGranzyme A mediated Apoptosis Pathway [Genes]    Caspase Cascade in Apoptosis [Genes]    Role of Mitochondria in Apoptotic Signaling [Genes]    Induction of apoptosis through DR3 and DR4/5 Death Receptors [Genes]    TNFR1 Signaling Pathway [Genes]    FAS signaling pathway ( CD95 ) [Genes]    Apoptotic DNA fragmentation and tissue homeostasis [Genes]    HIV-I Nef: negative effector of Fas and TNF [Genes]   
Pathways : KEGGApoptosis   
NDEx NetworkDFFB
Atlas of Cancer Signalling NetworkDFFB
Wikipedia pathwaysDFFB
Orthology - Evolution
OrthoDB1677
GeneTree (enSembl)ENSG00000169598
Phylogenetic Trees/Animal Genes : TreeFamDFFB
HOVERGENO76075
HOGENOMO76075
Homologs : HomoloGeneDFFB
Homology/Alignments : Family Browser (UCSC)DFFB
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDFFB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DFFB
dbVarDFFB
ClinVarDFFB
1000_GenomesDFFB 
Exome Variant ServerDFFB
ExAC (Exome Aggregation Consortium)DFFB (select the gene name)
Genetic variants : HAPMAP1677
Genomic Variants (DGV)DFFB [DGVbeta]
DECIPHER (Syndromes)1:3773831-3801993  ENSG00000169598
CONAN: Copy Number AnalysisDFFB 
Mutations
ICGC Data PortalDFFB 
TCGA Data PortalDFFB 
Broad Tumor PortalDFFB
OASIS PortalDFFB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDFFB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDFFB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DFFB
DgiDB (Drug Gene Interaction Database)DFFB
DoCM (Curated mutations)DFFB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DFFB (select a term)
intoGenDFFB
Cancer3DDFFB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601883   
Orphanet
MedgenDFFB
Genetic Testing Registry DFFB
NextProtO76075 [Medical]
TSGene1677
GENETestsDFFB
Huge Navigator DFFB [HugePedia]
snp3D : Map Gene to Disease1677
BioCentury BCIQDFFB
ClinGenDFFB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1677
Chemical/Pharm GKB GenePA27255
Clinical trialDFFB
Miscellaneous
canSAR (ICR)DFFB (select the gene name)
Probes
Litterature
PubMed57 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDFFB
EVEXDFFB
GoPubMedDFFB
iHOPDFFB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 14:58:46 CEST 2017

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