DFFB (DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase))

Identity

Other names	CAD
	CPAN
	DFF-40
	DFF2
	DFF40
HGNC	DFFB
Location	1p36.3
Location_base_pair	Starts at 3763705 and ends at 3791853 bp from pter ( according to hg18-March_2006).
Note	Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

External links

	Nomenclature
HGNC	DFFB   2773
Entrez_Gene	DFFB  1677  DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
	Cards
GeneCards	DFFB
Ensembl	DFFB [Search_View]   ENSG00000169598 [Gene_View]
Genatlas	DFFB
GeneLynx	DFFB
eGenome	DFFB
euGene	1677
	Genomic and cartography
GoldenPath	DFFB  -  1p36.3   chr1:3763705-3791853 +  1p36.32   [Description]    (hg18-March_2006)
Ensembl	DFFB - 1p36.32 [CytoView]
NCBI	Mapview
OMIM	Disease map [OMIM]
HomoloGene	DFFB
	Gene and transcription
Genbank	AB013918 [ ENTREZ ]
Genbank	AB028911 [ ENTREZ ]
Genbank	AB028912 [ ENTREZ ]
Genbank	AB028913 [ ENTREZ ]
Genbank	AF039210 [ ENTREZ ]
RefSeq	NM_004402 [ SRS ]    NM_004402 [ ENTREZ ]
RefSeq	AC_000044 [ SRS ]    AC_000044 [ ENTREZ ]
RefSeq	AC_000133 [ SRS ]    AC_000133 [ ENTREZ ]
RefSeq	NC_000001 [ SRS ]    NC_000001 [ ENTREZ ]
RefSeq	NT_004321 [ SRS ]    NT_004321 [ ENTREZ ]
RefSeq	NW_001838618 [ SRS ]    NW_001838618 [ ENTREZ ]
RefSeq	NW_923572 [ SRS ]    NW_923572 [ ENTREZ ]
AceView	DFFB AceView - NCBI
Unigene	Hs.133089 [ SRS ]    Hs.133089 [ NCBI ]     HS133089 [ spliceNest ]
Fast-db	2034 (alternative variants)
	Protein : pattern, domain, 3D structure
SwissProt	O76075 [ SRS]    O76075 [ EXPASY ]     O76075 [ INTERPRO ]     O76075 [ UNIPROT ]
Prosite	PS51135 CIDE_N [ SRS ]    PS51135 CIDE_N [ Expasy ]
Interpro	IPR015311 Apoptosis_DFF40 [ SRS ]    IPR015311 Apoptosis_DFF40 [ EBI ]
Interpro	IPR003508 CAD [ SRS ]    IPR003508 CAD [ EBI ]
CluSTr	O76075
Pfam	PF02017 CIDE-N [ SRS ]    PF02017 CIDE-N [ Sanger ]    pfam02017 [ NCBI-CDD ]
Pfam	PF09230 DFF40 [ SRS ]    PF09230 DFF40 [ Sanger ]    pfam09230 [ NCBI-CDD ]
Blocks	O76075
PDB	1IBX [ SRS ]    1IBX [ PdbSum ],   1IBX [ IMB ]   1IBX [ RSDB ]
HPRD	03532
	Protein Interaction databases
DIP	O76075
IntAct	O76075
	Polymorphism : SNP, mutations, diseases
OMIM	601883    [ map ]
GENECLINICS	601883
SNP	DFFB [dbSNP-NCBI]
SNP	NM_004402 [SNP-NCI]
SNP	DFFB [GeneSNPs - Utah]  DFFB] [HGBASE - SRS]
HAPMAP	DFFB [HAPMAP]
HGMD	DFFB
	General knowledge
Family Browser	DFFB [UCSC Family Browser]
SOURCE	NM_004402
SMD	Hs.133089
SAGE	Hs.133089
Enzyme	3.-.-.- [ Enzyme-Expasy ]   3.-.-.- [ Enzyme-SRS ]   3.-.-.- [ IntEnz-EBI ]   3.-.-.- [ BRENDA ]   3.-.-.- [ KEGG ]   3.-.-.- [ WIT ]
GO	nuclease activity [Amigo]  nuclease activity
GO	caspase-activated deoxyribonuclease activity [Amigo]  caspase-activated deoxyribonuclease activity
GO	protein binding [Amigo]  protein binding
GO	intracellular [Amigo]  intracellular
GO	nucleus [Amigo]  nucleus
GO	nucleoplasm [Amigo]  nucleoplasm
GO	cytoplasm [Amigo]  cytoplasm
GO	cytosol [Amigo]  cytosol
GO	DNA fragmentation during apoptosis [Amigo]  DNA fragmentation during apoptosis
GO	apoptosis [Amigo]  apoptosis
GO	intracellular signaling cascade [Amigo]  intracellular signaling cascade
GO	hydrolase activity [Amigo]  hydrolase activity
GO	enzyme binding [Amigo]  enzyme binding
GO	apoptotic chromosome condensation [Amigo]  apoptotic chromosome condensation
KEGG	Apoptosis
PubGene	DFFB
TreeFam	DFFB
CTD	1677 [Comparative ToxicoGenomics Database]
	Other databases
	Probes
Probe	DFFB Related clones (RZPD - Berlin)
	PubMed
PubMed	38 Pubmed reference(s) in Entrez

Genes in title	automatic search in PubMed
REVIEW articles	automatic search in PubMed
Last year publications	automatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written	09-2002	Dessen P, Le Minor S
Updated	03-2008	Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology

indexed on : Sat Oct 18 14:38:11 2008