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DGKB (diacylglycerol kinase beta)

Identity

Alias_namesDAGK2
diacylglycerol kinase, beta (90kD)
diacylglycerol kinase, beta 90kDa
Alias_symbol (synonym)KIAA0718
DGK
DGK-BETA
Other alias
HGNC (Hugo) DGKB
LocusID (NCBI) 1607
Atlas_Id 52993
Location 7p21.2  [Link to chromosome band 7p21]
Location_base_pair Starts at 14184674 and ends at 14881075 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DGKB (7p21.2) / DGKB (7p21.2)DGKB (7p21.2) / MALAT1 (11q13.1)DGKB (7p21.2) / MIPOL1 (14q13.3)
DGKB (7p21.2) / ZFAND6 (15q25.1)GFRA1 (10q25.3) / DGKB (7p21.2)HDAC9 (7p21.1) / DGKB (7p21.2)
MIPOL1 (14q13.3) / DGKB (7p21.2)GFRA1 10q25.3 / DGKB 7p21.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DGKB   2850
Cards
Entrez_Gene (NCBI)DGKB  1607  diacylglycerol kinase beta
AliasesDAGK2; DGK; DGK-BETA
GeneCards (Weizmann)DGKB
Ensembl hg19 (Hinxton)ENSG00000136267 [Gene_View]  chr7:14184674-14881075 [Contig_View]  DGKB [Vega]
Ensembl hg38 (Hinxton)ENSG00000136267 [Gene_View]  chr7:14184674-14881075 [Contig_View]  DGKB [Vega]
ICGC DataPortalENSG00000136267
TCGA cBioPortalDGKB
AceView (NCBI)DGKB
Genatlas (Paris)DGKB
WikiGenes1607
SOURCE (Princeton)DGKB
Genetics Home Reference (NIH)DGKB
Genomic and cartography
GoldenPath hg19 (UCSC)DGKB  -     chr7:14184674-14881075 -  7p21.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DGKB  -     7p21.2   [Description]    (hg38-Dec_2013)
EnsemblDGKB - 7p21.2 [CytoView hg19]  DGKB - 7p21.2 [CytoView hg38]
Mapping of homologs : NCBIDGKB [Mapview hg19]  DGKB [Mapview hg38]
OMIM604070   
Gene and transcription
Genbank (Entrez)AB018261 AK124856 AK295668 AK304719 BC105005
RefSeq transcript (Entrez)NM_004080 NM_145695
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_029494 NT_007819 NW_004929329
Consensus coding sequences : CCDS (NCBI)DGKB
Cluster EST : UnigeneHs.567255 [ NCBI ]
CGAP (NCI)Hs.567255
Alternative Splicing GalleryENSG00000136267
Gene ExpressionDGKB [ NCBI-GEO ]   DGKB [ EBI - ARRAY_EXPRESS ]   DGKB [ SEEK ]   DGKB [ MEM ]
Gene Expression Viewer (FireBrowse)DGKB [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1607
GTEX Portal (Tissue expression)DGKB
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y6T7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y6T7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y6T7
Splice isoforms : SwissVarQ9Y6T7
Catalytic activity : Enzyme2.7.1.107 [ Enzyme-Expasy ]   2.7.1.1072.7.1.107 [ IntEnz-EBI ]   2.7.1.107 [ BRENDA ]   2.7.1.107 [ KEGG ]   
PhosPhoSitePlusQ9Y6T7
Domaine pattern : Prosite (Expaxy)DAGK (PS50146)    EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)DAG_kinase_typeI_N    Diacylglycerol_kin_accessory    Diacylglycerol_kinase_cat_dom    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    NAD/diacylglycerol_kinase    PE/DAG-bd   
Domain families : Pfam (Sanger)C1_1 (PF00130)    DAG_kinase_N (PF14513)    DAGK_acc (PF00609)    DAGK_cat (PF00781)    EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam00130    pfam14513    pfam00609    pfam00781    pfam13499   
Domain families : Smart (EMBL)C1 (SM00109)  DAGKa (SM00045)  DAGKc (SM00046)  EFh (SM00054)  
Conserved Domain (NCBI)DGKB
DMDM Disease mutations1607
Blocks (Seattle)DGKB
SuperfamilyQ9Y6T7
Human Protein AtlasENSG00000136267
Peptide AtlasQ9Y6T7
HPRD06819
IPIIPI00002590   IPI00893505   IPI01009786   IPI00893041   IPI00374141   IPI00892828   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y6T7
IntAct (EBI)Q9Y6T7
FunCoupENSG00000136267
BioGRIDDGKB
STRING (EMBL)DGKB
ZODIACDGKB
Ontologies - Pathways
QuickGOQ9Y6T7
Ontology : AmiGOdiacylglycerol kinase activity  calcium ion binding  ATP binding  cytoplasm  plasma membrane  protein kinase C-activating G-protein coupled receptor signaling pathway  phosphorylation  platelet activation  intracellular signal transduction  
Ontology : EGO-EBIdiacylglycerol kinase activity  calcium ion binding  ATP binding  cytoplasm  plasma membrane  protein kinase C-activating G-protein coupled receptor signaling pathway  phosphorylation  platelet activation  intracellular signal transduction  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism    Phosphatidylinositol signaling system   
NDEx NetworkDGKB
Atlas of Cancer Signalling NetworkDGKB
Wikipedia pathwaysDGKB
Orthology - Evolution
OrthoDB1607
GeneTree (enSembl)ENSG00000136267
Phylogenetic Trees/Animal Genes : TreeFamDGKB
HOVERGENQ9Y6T7
HOGENOMQ9Y6T7
Homologs : HomoloGeneDGKB
Homology/Alignments : Family Browser (UCSC)DGKB
Gene fusions - Rearrangements
Fusion : MitelmanGFRA1/DGKB [10q25.3/7p21.2]  [t(7;10)(p21;q25)]  
Fusion: TCGAGFRA1 10q25.3 DGKB 7p21.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDGKB [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DGKB
dbVarDGKB
ClinVarDGKB
1000_GenomesDGKB 
Exome Variant ServerDGKB
ExAC (Exome Aggregation Consortium)DGKB (select the gene name)
Genetic variants : HAPMAP1607
Genomic Variants (DGV)DGKB [DGVbeta]
DECIPHER (Syndromes)7:14184674-14881075  ENSG00000136267
CONAN: Copy Number AnalysisDGKB 
Mutations
ICGC Data PortalDGKB 
TCGA Data PortalDGKB 
Broad Tumor PortalDGKB
OASIS PortalDGKB [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDGKB  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDGKB
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DGKB
DgiDB (Drug Gene Interaction Database)DGKB
DoCM (Curated mutations)DGKB (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DGKB (select a term)
intoGenDGKB
Cancer3DDGKB(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604070   
Orphanet
MedgenDGKB
Genetic Testing Registry DGKB
NextProtQ9Y6T7 [Medical]
TSGene1607
GENETestsDGKB
Huge Navigator DGKB [HugePedia]
snp3D : Map Gene to Disease1607
BioCentury BCIQDGKB
ClinGenDGKB
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1607
Chemical/Pharm GKB GenePA27311
Clinical trialDGKB
Miscellaneous
canSAR (ICR)DGKB (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDGKB
EVEXDGKB
GoPubMedDGKB
iHOPDGKB
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:03:10 CET 2017

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