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DGKG (diacylglycerol kinase gamma)

Identity

Alias_namesDAGK3
diacylglycerol kinase, gamma (90kD)
diacylglycerol kinase, gamma 90kDa
Other aliasDGK-GAMMA
HGNC (Hugo) DGKG
LocusID (NCBI) 1608
Atlas_Id 40300
Location 3q27.2  [Link to chromosome band 3q27]
Location_base_pair Starts at 186147201 and ends at 186362234 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DGKG (3q27.2) / BST1 (4p15.32)DGKG (3q27.2) / CRYGS (3q27.3)DGKG (3q27.2) / PCDH9 (13q21.32)
DGKG (3q27.2) / RUNX1 (21q22.12)DGKG (3q27.2) / TECPR2 (14q32.31)FAM107B (10p13) / DGKG (3q27.2)
GRINA (8q24.3) / DGKG (3q27.2)TPRG1 (3q28) / DGKG (3q27.2)DGKG 3q27.2 / CRYGS 3q27.3
TPRG1 3q28 / DGKG 3q27.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DGKG   2853
Cards
Entrez_Gene (NCBI)DGKG  1608  diacylglycerol kinase gamma
AliasesDAGK3; DGK-GAMMA
GeneCards (Weizmann)DGKG
Ensembl hg19 (Hinxton)ENSG00000058866 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000058866 [Gene_View]  chr3:186147201-186362234 [Contig_View]  DGKG [Vega]
ICGC DataPortalENSG00000058866
TCGA cBioPortalDGKG
AceView (NCBI)DGKG
Genatlas (Paris)DGKG
WikiGenes1608
SOURCE (Princeton)DGKG
Genetics Home Reference (NIH)DGKG
Genomic and cartography
GoldenPath hg38 (UCSC)DGKG  -     chr3:186147201-186362234 -  3q27.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DGKG  -     3q27.2   [Description]    (hg19-Feb_2009)
EnsemblDGKG - 3q27.2 [CytoView hg19]  DGKG - 3q27.2 [CytoView hg38]
Mapping of homologs : NCBIDGKG [Mapview hg19]  DGKG [Mapview hg38]
OMIM601854   
Gene and transcription
Genbank (Entrez)AB209033 AK304440 AK309682 AK314192 AY737485
RefSeq transcript (Entrez)NM_001080744 NM_001080745 NM_001346
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DGKG
Cluster EST : UnigeneHs.683449 [ NCBI ]
CGAP (NCI)Hs.683449
Alternative Splicing GalleryENSG00000058866
Gene ExpressionDGKG [ NCBI-GEO ]   DGKG [ EBI - ARRAY_EXPRESS ]   DGKG [ SEEK ]   DGKG [ MEM ]
Gene Expression Viewer (FireBrowse)DGKG [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1608
GTEX Portal (Tissue expression)DGKG
Protein : pattern, domain, 3D structure
UniProt/SwissProtP49619   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP49619  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP49619
Splice isoforms : SwissVarP49619
Catalytic activity : Enzyme2.7.1.107 [ Enzyme-Expasy ]   2.7.1.1072.7.1.107 [ IntEnz-EBI ]   2.7.1.107 [ BRENDA ]   2.7.1.107 [ KEGG ]   
PhosPhoSitePlusP49619
Domaine pattern : Prosite (Expaxy)DAGK (PS50146)    EF_HAND_1 (PS00018)    EF_HAND_2 (PS50222)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)DAG_kinase_typeI_N    Diacylglycerol_kin_accessory    Diacylglycerol_kinase_cat_dom    EF-hand-dom_pair    EF_Hand_1_Ca_BS    EF_hand_dom    NAD/diacylglycerol_kinase    PE/DAG-bd   
Domain families : Pfam (Sanger)C1_1 (PF00130)    DAG_kinase_N (PF14513)    DAGK_acc (PF00609)    DAGK_cat (PF00781)    EF-hand_7 (PF13499)   
Domain families : Pfam (NCBI)pfam00130    pfam14513    pfam00609    pfam00781    pfam13499   
Domain families : Smart (EMBL)C1 (SM00109)  DAGKa (SM00045)  DAGKc (SM00046)  EFh (SM00054)  
Conserved Domain (NCBI)DGKG
DMDM Disease mutations1608
Blocks (Seattle)DGKG
SuperfamilyP49619
Human Protein AtlasENSG00000058866
Peptide AtlasP49619
HPRD03510
IPIIPI00027658   IPI00216968   IPI00555984   IPI01010319   IPI01011634   IPI00925170   
Protein Interaction databases
DIP (DOE-UCLA)P49619
IntAct (EBI)P49619
FunCoupENSG00000058866
BioGRIDDGKG
STRING (EMBL)DGKG
ZODIACDGKG
Ontologies - Pathways
QuickGOP49619
Ontology : AmiGONAD+ kinase activity  diacylglycerol kinase activity  diacylglycerol kinase activity  calcium ion binding  ATP binding  cytoplasm  plasma membrane  signal transduction  protein kinase C-activating G-protein coupled receptor signaling pathway  platelet activation  intracellular signal transduction  glycerolipid metabolic process  lipid phosphorylation  neuron development  
Ontology : EGO-EBINAD+ kinase activity  diacylglycerol kinase activity  diacylglycerol kinase activity  calcium ion binding  ATP binding  cytoplasm  plasma membrane  signal transduction  protein kinase C-activating G-protein coupled receptor signaling pathway  platelet activation  intracellular signal transduction  glycerolipid metabolic process  lipid phosphorylation  neuron development  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism    Phosphatidylinositol signaling system   
NDEx NetworkDGKG
Atlas of Cancer Signalling NetworkDGKG
Wikipedia pathwaysDGKG
Orthology - Evolution
OrthoDB1608
GeneTree (enSembl)ENSG00000058866
Phylogenetic Trees/Animal Genes : TreeFamDGKG
HOVERGENP49619
HOGENOMP49619
Homologs : HomoloGeneDGKG
Homology/Alignments : Family Browser (UCSC)DGKG
Gene fusions - Rearrangements
Fusion : MitelmanDGKG/BST1 [3q27.2/4p15.32]  
Fusion : MitelmanDGKG/CRYGS [3q27.2/3q27.3]  [t(3;3)(q27;q27)]  
Fusion : MitelmanTPRG1/DGKG [3q28/3q27.2]  [t(3;3)(q27;q28)]  
Fusion: TCGADGKG 3q27.2 CRYGS 3q27.3 OV
Fusion: TCGATPRG1 3q28 DGKG 3q27.2 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDGKG [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DGKG
dbVarDGKG
ClinVarDGKG
1000_GenomesDGKG 
Exome Variant ServerDGKG
ExAC (Exome Aggregation Consortium)DGKG (select the gene name)
Genetic variants : HAPMAP1608
Genomic Variants (DGV)DGKG [DGVbeta]
DECIPHERDGKG [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDGKG 
Mutations
ICGC Data PortalDGKG 
TCGA Data PortalDGKG 
Broad Tumor PortalDGKG
OASIS PortalDGKG [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDGKG  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDGKG
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DGKG
DgiDB (Drug Gene Interaction Database)DGKG
DoCM (Curated mutations)DGKG (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DGKG (select a term)
intoGenDGKG
Cancer3DDGKG(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM601854   
Orphanet
MedgenDGKG
Genetic Testing Registry DGKG
NextProtP49619 [Medical]
TSGene1608
GENETestsDGKG
Target ValidationDGKG
Huge Navigator DGKG [HugePedia]
snp3D : Map Gene to Disease1608
BioCentury BCIQDGKG
ClinGenDGKG
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1608
Chemical/Pharm GKB GenePA27314
Clinical trialDGKG
Miscellaneous
canSAR (ICR)DGKG (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDGKG
EVEXDGKG
GoPubMedDGKG
iHOPDGKG
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:31:04 CEST 2017

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