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DGKH (diacylglycerol kinase, eta)

Identity

Alias_symbol (synonym)DGKeta
Other alias
HGNC (Hugo) DGKH
LocusID (NCBI) 160851
Atlas_Id 62456
Location 13q14.11  [Link to chromosome band 13q14]
Location_base_pair Starts at 42614172 and ends at 42817033 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
DGKH (13q14.11) / DGKH (13q14.11)DGKH (13q14.11) / MED13L (12q24.21)ENTPD1 (10q24.1) / DGKH (13q14.11)
GDA (9q21.13) / DGKH (13q14.11)MED13L (12q24.21) / DGKH (13q14.11)SOX6 (11p15.2) / DGKH (13q14.11)
UBQLN1 (9q21.32) / DGKH (13q14.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DGKH   2854
Cards
Entrez_Gene (NCBI)DGKH  160851  diacylglycerol kinase, eta
AliasesDGKeta
GeneCards (Weizmann)DGKH
Ensembl hg19 (Hinxton)ENSG00000102780 [Gene_View]  chr13:42614172-42817033 [Contig_View]  DGKH [Vega]
Ensembl hg38 (Hinxton)ENSG00000102780 [Gene_View]  chr13:42614172-42817033 [Contig_View]  DGKH [Vega]
ICGC DataPortalENSG00000102780
TCGA cBioPortalDGKH
AceView (NCBI)DGKH
Genatlas (Paris)DGKH
WikiGenes160851
SOURCE (Princeton)DGKH
Genetics Home Reference (NIH)DGKH
Genomic and cartography
GoldenPath hg19 (UCSC)DGKH  -     chr13:42614172-42817033 +  13q14.11   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DGKH  -     13q14.11   [Description]    (hg38-Dec_2013)
EnsemblDGKH - 13q14.11 [CytoView hg19]  DGKH - 13q14.11 [CytoView hg38]
Mapping of homologs : NCBIDGKH [Mapview hg19]  DGKH [Mapview hg38]
OMIM604071   
Gene and transcription
Genbank (Entrez)AB078967 AB078968 AI675047 AK054970 AK055427
RefSeq transcript (Entrez)NM_001204504 NM_001204505 NM_001204506 NM_001297429 NM_152910 NM_178009
RefSeq genomic (Entrez)NC_000013 NC_018924 NG_029191 NT_024524 NW_004929388
Consensus coding sequences : CCDS (NCBI)DGKH
Cluster EST : UnigeneHs.733239 [ NCBI ]
CGAP (NCI)Hs.733239
Alternative Splicing GalleryENSG00000102780
Gene ExpressionDGKH [ NCBI-GEO ]   DGKH [ EBI - ARRAY_EXPRESS ]   DGKH [ SEEK ]   DGKH [ MEM ]
Gene Expression Viewer (FireBrowse)DGKH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)160851
GTEX Portal (Tissue expression)DGKH
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86XP1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86XP1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86XP1
Splice isoforms : SwissVarQ86XP1
Catalytic activity : Enzyme2.7.1.107 [ Enzyme-Expasy ]   2.7.1.1072.7.1.107 [ IntEnz-EBI ]   2.7.1.107 [ BRENDA ]   2.7.1.107 [ KEGG ]   
PhosPhoSitePlusQ86XP1
Domaine pattern : Prosite (Expaxy)DAGK (PS50146)    PH_DOMAIN (PS50003)    SAM_DOMAIN (PS50105)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)Diacylglycerol_kin_accessory    Diacylglycerol_kinase_cat_dom    NAD/diacylglycerol_kinase    PE/DAG-bd    PH_domain    PH_like_dom    SAM    SAM/pointed    SAM_2   
Domain families : Pfam (Sanger)C1_1 (PF00130)    DAGK_acc (PF00609)    DAGK_cat (PF00781)    PH (PF00169)    SAM_2 (PF07647)   
Domain families : Pfam (NCBI)pfam00130    pfam00609    pfam00781    pfam00169    pfam07647   
Domain families : Smart (EMBL)C1 (SM00109)  DAGKa (SM00045)  DAGKc (SM00046)  PH (SM00233)  SAM (SM00454)  
Conserved Domain (NCBI)DGKH
DMDM Disease mutations160851
Blocks (Seattle)DGKH
SuperfamilyQ86XP1
Human Protein AtlasENSG00000102780
Peptide AtlasQ86XP1
HPRD07237
IPIIPI00745381   IPI00329264   IPI00759622   IPI01009220   IPI01008993   
Protein Interaction databases
DIP (DOE-UCLA)Q86XP1
IntAct (EBI)Q86XP1
FunCoupENSG00000102780
BioGRIDDGKH
STRING (EMBL)DGKH
ZODIACDGKH
Ontologies - Pathways
QuickGOQ86XP1
Ontology : AmiGOdiacylglycerol kinase activity  ATP binding  nucleus  cytoplasm  endosome  plasma membrane  protein kinase C-activating G-protein coupled receptor signaling pathway  blood coagulation  phosphorylation  platelet activation  nuclear membrane  intracellular signal transduction  metal ion binding  protein oligomerization  
Ontology : EGO-EBIdiacylglycerol kinase activity  ATP binding  nucleus  cytoplasm  endosome  plasma membrane  protein kinase C-activating G-protein coupled receptor signaling pathway  blood coagulation  phosphorylation  platelet activation  nuclear membrane  intracellular signal transduction  metal ion binding  protein oligomerization  
Pathways : KEGGGlycerolipid metabolism    Glycerophospholipid metabolism    Phosphatidylinositol signaling system   
NDEx NetworkDGKH
Atlas of Cancer Signalling NetworkDGKH
Wikipedia pathwaysDGKH
Orthology - Evolution
OrthoDB160851
GeneTree (enSembl)ENSG00000102780
Phylogenetic Trees/Animal Genes : TreeFamDGKH
HOVERGENQ86XP1
HOGENOMQ86XP1
Homologs : HomoloGeneDGKH
Homology/Alignments : Family Browser (UCSC)DGKH
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDGKH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DGKH
dbVarDGKH
ClinVarDGKH
1000_GenomesDGKH 
Exome Variant ServerDGKH
ExAC (Exome Aggregation Consortium)DGKH (select the gene name)
Genetic variants : HAPMAP160851
Genomic Variants (DGV)DGKH [DGVbeta]
DECIPHER (Syndromes)13:42614172-42817033  ENSG00000102780
CONAN: Copy Number AnalysisDGKH 
Mutations
ICGC Data PortalDGKH 
TCGA Data PortalDGKH 
Broad Tumor PortalDGKH
OASIS PortalDGKH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDGKH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDGKH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DGKH
DgiDB (Drug Gene Interaction Database)DGKH
DoCM (Curated mutations)DGKH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DGKH (select a term)
intoGenDGKH
Cancer3DDGKH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604071   
Orphanet
MedgenDGKH
Genetic Testing Registry DGKH
NextProtQ86XP1 [Medical]
TSGene160851
GENETestsDGKH
Huge Navigator DGKH [HugePedia]
snp3D : Map Gene to Disease160851
BioCentury BCIQDGKH
ClinGenDGKH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD160851
Chemical/Pharm GKB GenePA27315
Clinical trialDGKH
Miscellaneous
canSAR (ICR)DGKH (select the gene name)
Probes
Litterature
PubMed29 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDGKH
EVEXDGKH
GoPubMedDGKH
iHOPDGKH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:01:35 CET 2017

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