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DGKK (diacylglycerol kinase, kappa)

Identity

Other alias-
HGNC (Hugo) DGKK
LocusID (NCBI) 139189
Atlas_Id 62458
Location Xp11.22  [Link to chromosome band Xp11]
Location_base_pair Starts at 50108406 and ends at 50213737 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DGKK   32395
Cards
Entrez_Gene (NCBI)DGKK  139189  diacylglycerol kinase, kappa
Aliases
GeneCards (Weizmann)DGKK
Ensembl hg19 (Hinxton)ENSG00000274588 [Gene_View]  chrX:50108406-50213737 [Contig_View]  DGKK [Vega]
Ensembl hg38 (Hinxton)ENSG00000274588 [Gene_View]  chrX:50108406-50213737 [Contig_View]  DGKK [Vega]
ICGC DataPortalENSG00000274588
TCGA cBioPortalDGKK
AceView (NCBI)DGKK
Genatlas (Paris)DGKK
WikiGenes139189
SOURCE (Princeton)DGKK
Genetics Home Reference (NIH)DGKK
Genomic and cartography
GoldenPath hg19 (UCSC)DGKK  -     chrX:50108406-50213737 -  Xp11.22   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DGKK  -     Xp11.22   [Description]    (hg38-Dec_2013)
EnsemblDGKK - Xp11.22 [CytoView hg19]  DGKK - Xp11.22 [CytoView hg38]
Mapping of homologs : NCBIDGKK [Mapview hg19]  DGKK [Mapview hg38]
OMIM300837   
Gene and transcription
Genbank (Entrez)AB183864 AI591038 BC137319 BC137320 DB728104
RefSeq transcript (Entrez)NM_001013742
RefSeq genomic (Entrez)NC_000023 NC_018934 NG_033143 NT_011630 NW_004929441
Consensus coding sequences : CCDS (NCBI)DGKK
Cluster EST : UnigeneHs.631770 [ NCBI ]
CGAP (NCI)Hs.631770
Alternative Splicing GalleryENSG00000274588
Gene ExpressionDGKK [ NCBI-GEO ]   DGKK [ EBI - ARRAY_EXPRESS ]   DGKK [ SEEK ]   DGKK [ MEM ]
Gene Expression Viewer (FireBrowse)DGKK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)139189
GTEX Portal (Tissue expression)DGKK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5KSL6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5KSL6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5KSL6
Splice isoforms : SwissVarQ5KSL6
Catalytic activity : Enzyme2.7.1.107 [ Enzyme-Expasy ]   2.7.1.1072.7.1.107 [ IntEnz-EBI ]   2.7.1.107 [ BRENDA ]   2.7.1.107 [ KEGG ]   
PhosPhoSitePlusQ5KSL6
Domaine pattern : Prosite (Expaxy)DAGK (PS50146)    PH_DOMAIN (PS50003)    ZF_DAG_PE_1 (PS00479)    ZF_DAG_PE_2 (PS50081)   
Domains : Interpro (EBI)Diacylglycerol_kin_accessory    Diacylglycerol_kinase_cat_dom    NAD/diacylglycerol_kinase    PE/DAG-bd    PH_domain    PH_like_dom   
Domain families : Pfam (Sanger)C1_1 (PF00130)    DAGK_acc (PF00609)    DAGK_cat (PF00781)    PH (PF00169)   
Domain families : Pfam (NCBI)pfam00130    pfam00609    pfam00781    pfam00169   
Domain families : Smart (EMBL)C1 (SM00109)  DAGKa (SM00045)  DAGKc (SM00046)  PH (SM00233)  
Conserved Domain (NCBI)DGKK
DMDM Disease mutations139189
Blocks (Seattle)DGKK
SuperfamilyQ5KSL6
Human Protein AtlasENSG00000274588
Peptide AtlasQ5KSL6
HPRD10299
IPIIPI00046309   
Protein Interaction databases
DIP (DOE-UCLA)Q5KSL6
IntAct (EBI)Q5KSL6
FunCoupENSG00000274588
BioGRIDDGKK
STRING (EMBL)DGKK
ZODIACDGKK
Ontologies - Pathways
QuickGOQ5KSL6
Ontology : AmiGOdiacylglycerol kinase activity  ATP binding  cytoplasm  plasma membrane  plasma membrane  response to oxidative stress  protein kinase C-activating G-protein coupled receptor signaling pathway  blood coagulation  phosphorylation  platelet activation  intracellular signal transduction  diacylglycerol metabolic process  metal ion binding  
Ontology : EGO-EBIdiacylglycerol kinase activity  ATP binding  cytoplasm  plasma membrane  plasma membrane  response to oxidative stress  protein kinase C-activating G-protein coupled receptor signaling pathway  blood coagulation  phosphorylation  platelet activation  intracellular signal transduction  diacylglycerol metabolic process  metal ion binding  
NDEx NetworkDGKK
Atlas of Cancer Signalling NetworkDGKK
Wikipedia pathwaysDGKK
Orthology - Evolution
OrthoDB139189
GeneTree (enSembl)ENSG00000274588
Phylogenetic Trees/Animal Genes : TreeFamDGKK
HOVERGENQ5KSL6
HOGENOMQ5KSL6
Homologs : HomoloGeneDGKK
Homology/Alignments : Family Browser (UCSC)DGKK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDGKK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DGKK
dbVarDGKK
ClinVarDGKK
1000_GenomesDGKK 
Exome Variant ServerDGKK
ExAC (Exome Aggregation Consortium)DGKK (select the gene name)
Genetic variants : HAPMAP139189
Genomic Variants (DGV)DGKK [DGVbeta]
DECIPHER (Syndromes)X:50108406-50213737  ENSG00000274588
CONAN: Copy Number AnalysisDGKK 
Mutations
ICGC Data PortalDGKK 
TCGA Data PortalDGKK 
Broad Tumor PortalDGKK
OASIS PortalDGKK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDGKK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDGKK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DGKK
DgiDB (Drug Gene Interaction Database)DGKK
DoCM (Curated mutations)DGKK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DGKK (select a term)
intoGenDGKK
Cancer3DDGKK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM300837   
Orphanet
MedgenDGKK
Genetic Testing Registry DGKK
NextProtQ5KSL6 [Medical]
TSGene139189
GENETestsDGKK
Huge Navigator DGKK [HugePedia]
snp3D : Map Gene to Disease139189
BioCentury BCIQDGKK
ClinGenDGKK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD139189
Chemical/Pharm GKB GenePA142671978
Clinical trialDGKK
Miscellaneous
canSAR (ICR)DGKK (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDGKK
EVEXDGKK
GoPubMedDGKK
iHOPDGKK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:01:35 CET 2017

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