Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DGUOK (deoxyguanosine kinase)

Identity

Alias_symbol (synonym)dGK
Other aliasMTDPS3
NCPH
PEOB4
HGNC (Hugo) DGUOK
LocusID (NCBI) 1716
Atlas_Id 62459
Location 2p13.1  [Link to chromosome band 2p13]
Location_base_pair Starts at 73926826 and ends at 73958961 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DGUOK (2p13.1) / ACTG2 (2p13.1)DGUOK (2p13.1) / CFLAR (2q33.1)DGUOK (2p13.1) / PRKD2 (19q13.32)
DGUOK (2p13.1) / STAMBP (2p13.1)OLFM4 (13q14.3) / DGUOK (2p13.1)RBM45 (2q31.2) / DGUOK (2p13.1)
TET3 (2p13.1) / DGUOK (2p13.1)UBE2A (Xq24) / DGUOK (2p13.1)DGUOK ACTG2
DGUOK STAMBPTET3 DGUOKRBM45 DGUOK

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DGUOK   2858
Cards
Entrez_Gene (NCBI)DGUOK  1716  deoxyguanosine kinase
AliasesMTDPS3; NCPH; PEOB4; dGK
GeneCards (Weizmann)DGUOK
Ensembl hg19 (Hinxton)ENSG00000114956 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000114956 [Gene_View]  chr2:73926826-73958961 [Contig_View]  DGUOK [Vega]
ICGC DataPortalENSG00000114956
TCGA cBioPortalDGUOK
AceView (NCBI)DGUOK
Genatlas (Paris)DGUOK
WikiGenes1716
SOURCE (Princeton)DGUOK
Genetics Home Reference (NIH)DGUOK
Genomic and cartography
GoldenPath hg38 (UCSC)DGUOK  -     chr2:73926826-73958961 +  2p13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DGUOK  -     2p13.1   [Description]    (hg19-Feb_2009)
EnsemblDGUOK - 2p13.1 [CytoView hg19]  DGUOK - 2p13.1 [CytoView hg38]
Mapping of homologs : NCBIDGUOK [Mapview hg19]  DGUOK [Mapview hg38]
OMIM251880   601465   617068   617070   
Gene and transcription
Genbank (Entrez)AI201630 AU099795 AV760728 BC001121 BC015757
RefSeq transcript (Entrez)NM_001318859 NM_001318860 NM_001318861 NM_001318862 NM_001318863 NM_001929 NM_080915 NM_080916 NM_080917 NM_080918
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DGUOK
Cluster EST : UnigeneHs.469022 [ NCBI ]
CGAP (NCI)Hs.469022
Alternative Splicing GalleryENSG00000114956
Gene ExpressionDGUOK [ NCBI-GEO ]   DGUOK [ EBI - ARRAY_EXPRESS ]   DGUOK [ SEEK ]   DGUOK [ MEM ]
Gene Expression Viewer (FireBrowse)DGUOK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1716
GTEX Portal (Tissue expression)DGUOK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ16854   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ16854  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ16854
Splice isoforms : SwissVarQ16854
Catalytic activity : Enzyme2.7.1.113 [ Enzyme-Expasy ]   2.7.1.1132.7.1.113 [ IntEnz-EBI ]   2.7.1.113 [ BRENDA ]   2.7.1.113 [ KEGG ]   
PhosPhoSitePlusQ16854
Domains : Interpro (EBI)DCK/DGK    DNK_dom    P-loop_NTPase   
Domain families : Pfam (Sanger)dNK (PF01712)   
Domain families : Pfam (NCBI)pfam01712   
Conserved Domain (NCBI)DGUOK
DMDM Disease mutations1716
Blocks (Seattle)DGUOK
PDB (SRS)2OCP   
PDB (PDBSum)2OCP   
PDB (IMB)2OCP   
PDB (RSDB)2OCP   
Structural Biology KnowledgeBase2OCP   
SCOP (Structural Classification of Proteins)2OCP   
CATH (Classification of proteins structures)2OCP   
SuperfamilyQ16854
Human Protein AtlasENSG00000114956
Peptide AtlasQ16854
HPRD03273
IPIIPI00004461   IPI00221317   IPI00221318   IPI00221319   IPI00221320   IPI00953397   IPI00031642   
Protein Interaction databases
DIP (DOE-UCLA)Q16854
IntAct (EBI)Q16854
FunCoupENSG00000114956
BioGRIDDGUOK
STRING (EMBL)DGUOK
ZODIACDGUOK
Ontologies - Pathways
QuickGOQ16854
Ontology : AmiGOdeoxyguanosine kinase activity  ATP binding  nucleus  mitochondrion  mitochondrial matrix  cytosol  protein phosphorylation  guanosine metabolic process  deoxyribonucleoside monophosphate biosynthetic process  nucleotide biosynthetic process  negative regulation of neuron projection development  nucleoside kinase activity  purine-containing compound salvage  dGTP metabolic process  purine deoxyribonucleoside metabolic process  
Ontology : EGO-EBIdeoxyguanosine kinase activity  ATP binding  nucleus  mitochondrion  mitochondrial matrix  cytosol  protein phosphorylation  guanosine metabolic process  deoxyribonucleoside monophosphate biosynthetic process  nucleotide biosynthetic process  negative regulation of neuron projection development  nucleoside kinase activity  purine-containing compound salvage  dGTP metabolic process  purine deoxyribonucleoside metabolic process  
Pathways : KEGGPurine metabolism   
NDEx NetworkDGUOK
Atlas of Cancer Signalling NetworkDGUOK
Wikipedia pathwaysDGUOK
Orthology - Evolution
OrthoDB1716
GeneTree (enSembl)ENSG00000114956
Phylogenetic Trees/Animal Genes : TreeFamDGUOK
HOVERGENQ16854
HOGENOMQ16854
Homologs : HomoloGeneDGUOK
Homology/Alignments : Family Browser (UCSC)DGUOK
Gene fusions - Rearrangements
Fusion: TCGADGUOK ACTG2
Fusion: TCGADGUOK STAMBP
Fusion: TCGATET3 DGUOK
Fusion: TCGARBM45 DGUOK
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDGUOK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DGUOK
dbVarDGUOK
ClinVarDGUOK
1000_GenomesDGUOK 
Exome Variant ServerDGUOK
ExAC (Exome Aggregation Consortium)DGUOK (select the gene name)
Genetic variants : HAPMAP1716
Genomic Variants (DGV)DGUOK [DGVbeta]
DECIPHERDGUOK [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDGUOK 
Mutations
ICGC Data PortalDGUOK 
TCGA Data PortalDGUOK 
Broad Tumor PortalDGUOK
OASIS PortalDGUOK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDGUOK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDGUOK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DGUOK
DgiDB (Drug Gene Interaction Database)DGUOK
DoCM (Curated mutations)DGUOK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DGUOK (select a term)
intoGenDGUOK
Cancer3DDGUOK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM251880    601465    617068    617070   
Orphanet20419    21925   
MedgenDGUOK
Genetic Testing Registry DGUOK
NextProtQ16854 [Medical]
TSGene1716
GENETestsDGUOK
Target ValidationDGUOK
Huge Navigator DGUOK [HugePedia]
snp3D : Map Gene to Disease1716
BioCentury BCIQDGUOK
ClinGenDGUOK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1716
Chemical/Pharm GKB GenePA27319
Clinical trialDGUOK
Miscellaneous
canSAR (ICR)DGUOK (select the gene name)
Probes
Litterature
PubMed44 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDGUOK
EVEXDGUOK
GoPubMedDGUOK
iHOPDGUOK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:06:13 CEST 2017

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