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DHDH (dihydrodiol dehydrogenase)

Identity

Alias_names2-dihydrobenzene-1
2-diol dehydrogenase
Alias_symbol (synonym)HUM2DD
Other alias2DD
HGNC (Hugo) DHDH
LocusID (NCBI) 27294
Atlas_Id 50803
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 48933682 and ends at 48944969 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
AP2A1 (19q13.33) / DHDH (19q13.33)BAX (19q13.33) / DHDH (19q13.33)AP2A1 19q13.33 / DHDH 19q13.33
BAX 19q13.33 / DHDH 19q13.33

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHDH   17887
Cards
Entrez_Gene (NCBI)DHDH  27294  dihydrodiol dehydrogenase
Aliases2DD; HUM2DD
GeneCards (Weizmann)DHDH
Ensembl hg19 (Hinxton)ENSG00000104808 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000104808 [Gene_View]  chr19:48933682-48944969 [Contig_View]  DHDH [Vega]
ICGC DataPortalENSG00000104808
TCGA cBioPortalDHDH
AceView (NCBI)DHDH
Genatlas (Paris)DHDH
WikiGenes27294
SOURCE (Princeton)DHDH
Genetics Home Reference (NIH)DHDH
Genomic and cartography
GoldenPath hg38 (UCSC)DHDH  -     chr19:48933682-48944969 +  19q13.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHDH  -     19q13.33   [Description]    (hg19-Feb_2009)
EnsemblDHDH - 19q13.33 [CytoView hg19]  DHDH - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBIDHDH [Mapview hg19]  DHDH [Mapview hg38]
OMIM606377   
Gene and transcription
Genbank (Entrez)AB021933 BC032730 BF510979 DQ890882 DQ894036
RefSeq transcript (Entrez)NM_014475
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DHDH
Cluster EST : UnigeneHs.631555 [ NCBI ]
CGAP (NCI)Hs.631555
Alternative Splicing GalleryENSG00000104808
Gene ExpressionDHDH [ NCBI-GEO ]   DHDH [ EBI - ARRAY_EXPRESS ]   DHDH [ SEEK ]   DHDH [ MEM ]
Gene Expression Viewer (FireBrowse)DHDH [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27294
GTEX Portal (Tissue expression)DHDH
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UQ10   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UQ10  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UQ10
Splice isoforms : SwissVarQ9UQ10
Catalytic activity : Enzyme1.3.1.20 [ Enzyme-Expasy ]   1.3.1.201.3.1.20 [ IntEnz-EBI ]   1.3.1.20 [ BRENDA ]   1.3.1.20 [ KEGG ]   
PhosPhoSitePlusQ9UQ10
Domains : Interpro (EBI)NAD(P)-bd_dom    Oxidoreductase_N   
Domain families : Pfam (Sanger)GFO_IDH_MocA (PF01408)   
Domain families : Pfam (NCBI)pfam01408   
Conserved Domain (NCBI)DHDH
DMDM Disease mutations27294
Blocks (Seattle)DHDH
SuperfamilyQ9UQ10
Human Protein AtlasENSG00000104808
Peptide AtlasQ9UQ10
HPRD08399
IPIIPI00004470   IPI00974413   IPI00974014   IPI00976026   
Protein Interaction databases
DIP (DOE-UCLA)Q9UQ10
IntAct (EBI)Q9UQ10
FunCoupENSG00000104808
BioGRIDDHDH
STRING (EMBL)DHDH
ZODIACDHDH
Ontologies - Pathways
QuickGOQ9UQ10
Ontology : AmiGOcarbohydrate metabolic process  NAD(P)+ transhydrogenase activity  electron carrier activity  D-xylose catabolic process  trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity  D-xylose 1-dehydrogenase (NADP+) activity  oxidation-reduction process  
Ontology : EGO-EBIcarbohydrate metabolic process  NAD(P)+ transhydrogenase activity  electron carrier activity  D-xylose catabolic process  trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity  D-xylose 1-dehydrogenase (NADP+) activity  oxidation-reduction process  
Pathways : KEGGPentose and glucuronate interconversions    Metabolism of xenobiotics by cytochrome P450   
NDEx NetworkDHDH
Atlas of Cancer Signalling NetworkDHDH
Wikipedia pathwaysDHDH
Orthology - Evolution
OrthoDB27294
GeneTree (enSembl)ENSG00000104808
Phylogenetic Trees/Animal Genes : TreeFamDHDH
HOVERGENQ9UQ10
HOGENOMQ9UQ10
Homologs : HomoloGeneDHDH
Homology/Alignments : Family Browser (UCSC)DHDH
Gene fusions - Rearrangements
Fusion : MitelmanAP2A1/DHDH [19q13.33/19q13.33]  [t(19;19)(q13;q13)]  
Fusion : MitelmanBAX/DHDH [19q13.33/19q13.33]  [t(19;19)(q13;q13)]  
Fusion: TCGAAP2A1 19q13.33 DHDH 19q13.33 BRCA
Fusion: TCGABAX 19q13.33 DHDH 19q13.33 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHDH [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHDH
dbVarDHDH
ClinVarDHDH
1000_GenomesDHDH 
Exome Variant ServerDHDH
ExAC (Exome Aggregation Consortium)DHDH (select the gene name)
Genetic variants : HAPMAP27294
Genomic Variants (DGV)DHDH [DGVbeta]
DECIPHERDHDH [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHDH 
Mutations
ICGC Data PortalDHDH 
TCGA Data PortalDHDH 
Broad Tumor PortalDHDH
OASIS PortalDHDH [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHDH  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHDH
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHDH
DgiDB (Drug Gene Interaction Database)DHDH
DoCM (Curated mutations)DHDH (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHDH (select a term)
intoGenDHDH
Cancer3DDHDH(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606377   
Orphanet
MedgenDHDH
Genetic Testing Registry DHDH
NextProtQ9UQ10 [Medical]
TSGene27294
GENETestsDHDH
Target ValidationDHDH
Huge Navigator DHDH [HugePedia]
snp3D : Map Gene to Disease27294
BioCentury BCIQDHDH
ClinGenDHDH
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27294
Chemical/Pharm GKB GenePA27322
Clinical trialDHDH
Miscellaneous
canSAR (ICR)DHDH (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHDH
EVEXDHDH
GoPubMedDHDH
iHOPDHDH
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 12:31:05 CEST 2017

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