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DHRS1 (dehydrogenase/reductase 1)

Identity

Alias_namesdehydrogenase/reductase (SDR family) member 1
Alias_symbol (synonym)FLJ25430
MGC20204
SDR19C1
Other alias
HGNC (Hugo) DHRS1
LocusID (NCBI) 115817
Atlas_Id 62464
Location 14q12  [Link to chromosome band 14q12]
Location_base_pair Starts at 24290598 and ends at 24299833 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DHRS1 (14q12) / METTL3 (14q11.2)DHRS1 (14q12) / RABGGTA (14q12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHRS1   16445
Cards
Entrez_Gene (NCBI)DHRS1  115817  dehydrogenase/reductase 1
AliasesSDR19C1
GeneCards (Weizmann)DHRS1
Ensembl hg19 (Hinxton)ENSG00000157379 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000157379 [Gene_View]  chr14:24290598-24299833 [Contig_View]  DHRS1 [Vega]
ICGC DataPortalENSG00000157379
TCGA cBioPortalDHRS1
AceView (NCBI)DHRS1
Genatlas (Paris)DHRS1
WikiGenes115817
SOURCE (Princeton)DHRS1
Genetics Home Reference (NIH)DHRS1
Genomic and cartography
GoldenPath hg38 (UCSC)DHRS1  -     chr14:24290598-24299833 -  14q12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHRS1  -     14q12   [Description]    (hg19-Feb_2009)
EnsemblDHRS1 - 14q12 [CytoView hg19]  DHRS1 - 14q12 [CytoView hg38]
Mapping of homologs : NCBIDHRS1 [Mapview hg19]  DHRS1 [Mapview hg38]
OMIM610410   
Gene and transcription
Genbank (Entrez)AF418205 AK058159 AK126383 AL050217 AL833917
RefSeq transcript (Entrez)NM_001136050 NM_138452
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DHRS1
Cluster EST : UnigeneHs.348350 [ NCBI ]
CGAP (NCI)Hs.348350
Alternative Splicing GalleryENSG00000157379
Gene ExpressionDHRS1 [ NCBI-GEO ]   DHRS1 [ EBI - ARRAY_EXPRESS ]   DHRS1 [ SEEK ]   DHRS1 [ MEM ]
Gene Expression Viewer (FireBrowse)DHRS1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)115817
GTEX Portal (Tissue expression)DHRS1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96LJ7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96LJ7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96LJ7
Splice isoforms : SwissVarQ96LJ7
Catalytic activity : Enzyme1.1.-.- [ Enzyme-Expasy ]   1.1.-.-1.1.-.- [ IntEnz-EBI ]   1.1.-.- [ BRENDA ]   1.1.-.- [ KEGG ]   
PhosPhoSitePlusQ96LJ7
Domains : Interpro (EBI)NAD(P)-bd_dom    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)DHRS1
DMDM Disease mutations115817
Blocks (Seattle)DHRS1
PDB (SRS)2QQ5   
PDB (PDBSum)2QQ5   
PDB (IMB)2QQ5   
PDB (RSDB)2QQ5   
Structural Biology KnowledgeBase2QQ5   
SCOP (Structural Classification of Proteins)2QQ5   
CATH (Classification of proteins structures)2QQ5   
SuperfamilyQ96LJ7
Human Protein AtlasENSG00000157379
Peptide AtlasQ96LJ7
HPRD09914
IPIIPI00065063   
Protein Interaction databases
DIP (DOE-UCLA)Q96LJ7
IntAct (EBI)Q96LJ7
FunCoupENSG00000157379
BioGRIDDHRS1
STRING (EMBL)DHRS1
ZODIACDHRS1
Ontologies - Pathways
QuickGOQ96LJ7
Ontology : AmiGOprotein binding  mitochondrial inner membrane  endoplasmic reticulum  oxidoreductase activity  oxidation-reduction process  
Ontology : EGO-EBIprotein binding  mitochondrial inner membrane  endoplasmic reticulum  oxidoreductase activity  oxidation-reduction process  
NDEx NetworkDHRS1
Atlas of Cancer Signalling NetworkDHRS1
Wikipedia pathwaysDHRS1
Orthology - Evolution
OrthoDB115817
GeneTree (enSembl)ENSG00000157379
Phylogenetic Trees/Animal Genes : TreeFamDHRS1
HOVERGENQ96LJ7
HOGENOMQ96LJ7
Homologs : HomoloGeneDHRS1
Homology/Alignments : Family Browser (UCSC)DHRS1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHRS1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHRS1
dbVarDHRS1
ClinVarDHRS1
1000_GenomesDHRS1 
Exome Variant ServerDHRS1
ExAC (Exome Aggregation Consortium)DHRS1 (select the gene name)
Genetic variants : HAPMAP115817
Genomic Variants (DGV)DHRS1 [DGVbeta]
DECIPHERDHRS1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHRS1 
Mutations
ICGC Data PortalDHRS1 
TCGA Data PortalDHRS1 
Broad Tumor PortalDHRS1
OASIS PortalDHRS1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHRS1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHRS1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch DHRS1
DgiDB (Drug Gene Interaction Database)DHRS1
DoCM (Curated mutations)DHRS1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHRS1 (select a term)
intoGenDHRS1
Cancer3DDHRS1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM610410   
Orphanet
MedgenDHRS1
Genetic Testing Registry DHRS1
NextProtQ96LJ7 [Medical]
TSGene115817
GENETestsDHRS1
Target ValidationDHRS1
Huge Navigator DHRS1 [HugePedia]
snp3D : Map Gene to Disease115817
BioCentury BCIQDHRS1
ClinGenDHRS1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD115817
Chemical/Pharm GKB GenePA134914102
Clinical trialDHRS1
Miscellaneous
canSAR (ICR)DHRS1 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHRS1
EVEXDHRS1
GoPubMedDHRS1
iHOPDHRS1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed Jun 7 15:45:50 CEST 2017

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