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DHRS3 (dehydrogenase/reductase 3)

Identity

Alias_namesmember 1
Alias_symbol (synonym)retSDR1
Rsdr1
SDR1
RDH17
SDR16C1
Other aliasDD83.1
HGNC (Hugo) DHRS3
LocusID (NCBI) 9249
Atlas_Id 50385
Location 1p36.21  [Link to chromosome band 1p36]
Location_base_pair Starts at 12567910 and ends at 12616784 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
CAMTA1 (1p36.31) / DHRS3 (1p36.22)CAMTA1 1p36.31 / DHRS3 1p36.22

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHRS3   17693
Cards
Entrez_Gene (NCBI)DHRS3  9249  dehydrogenase/reductase 3
AliasesDD83.1; RDH17; Rsdr1; SDR1; 
SDR16C1; retSDR1
GeneCards (Weizmann)DHRS3
Ensembl hg19 (Hinxton)ENSG00000162496 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000162496 [Gene_View]  chr1:12567910-12616784 [Contig_View]  DHRS3 [Vega]
ICGC DataPortalENSG00000162496
TCGA cBioPortalDHRS3
AceView (NCBI)DHRS3
Genatlas (Paris)DHRS3
WikiGenes9249
SOURCE (Princeton)DHRS3
Genetics Home Reference (NIH)DHRS3
Genomic and cartography
GoldenPath hg38 (UCSC)DHRS3  -     chr1:12567910-12616784 -  1p36.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHRS3  -     1p36.21   [Description]    (hg19-Feb_2009)
EnsemblDHRS3 - 1p36.21 [CytoView hg19]  DHRS3 - 1p36.21 [CytoView hg38]
Mapping of homologs : NCBIDHRS3 [Mapview hg19]  DHRS3 [Mapview hg38]
OMIM612830   
Gene and transcription
Genbank (Entrez)AF061741 AK222593 AK225057 AK309282 AK310202
RefSeq transcript (Entrez)NM_001319225 NM_001324370 NM_004753
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DHRS3
Cluster EST : UnigeneHs.708470 [ NCBI ]
CGAP (NCI)Hs.708470
Alternative Splicing GalleryENSG00000162496
Gene ExpressionDHRS3 [ NCBI-GEO ]   DHRS3 [ EBI - ARRAY_EXPRESS ]   DHRS3 [ SEEK ]   DHRS3 [ MEM ]
Gene Expression Viewer (FireBrowse)DHRS3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9249
GTEX Portal (Tissue expression)DHRS3
Protein : pattern, domain, 3D structure
UniProt/SwissProtO75911   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO75911  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO75911
Splice isoforms : SwissVarO75911
Catalytic activity : Enzyme1.1.1.300 [ Enzyme-Expasy ]   1.1.1.3001.1.1.300 [ IntEnz-EBI ]   1.1.1.300 [ BRENDA ]   1.1.1.300 [ KEGG ]   
PhosPhoSitePlusO75911
Domains : Interpro (EBI)DHRS3    NAD(P)-bd_dom    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)DHRS3
DMDM Disease mutations9249
Blocks (Seattle)DHRS3
SuperfamilyO75911
Human Protein AtlasENSG00000162496
Peptide AtlasO75911
HPRD09915
IPIIPI00006250   IPI00432717   IPI00641331   
Protein Interaction databases
DIP (DOE-UCLA)O75911
IntAct (EBI)O75911
FunCoupENSG00000162496
BioGRIDDHRS3
STRING (EMBL)DHRS3
ZODIACDHRS3
Ontologies - Pathways
QuickGOO75911
Ontology : AmiGOnucleotide binding  retinoid metabolic process  outflow tract morphogenesis  retinol dehydrogenase activity  endoplasmic reticulum membrane  visual perception  electron carrier activity  integral component of membrane  regulation of ossification  retinol metabolic process  photoreceptor outer segment membrane  negative regulation of retinoic acid receptor signaling pathway  NADP-retinol dehydrogenase activity  oxidation-reduction process  palate development  bone morphogenesis  cardiac septum morphogenesis  
Ontology : EGO-EBInucleotide binding  retinoid metabolic process  outflow tract morphogenesis  retinol dehydrogenase activity  endoplasmic reticulum membrane  visual perception  electron carrier activity  integral component of membrane  regulation of ossification  retinol metabolic process  photoreceptor outer segment membrane  negative regulation of retinoic acid receptor signaling pathway  NADP-retinol dehydrogenase activity  oxidation-reduction process  palate development  bone morphogenesis  cardiac septum morphogenesis  
Pathways : KEGGRetinol metabolism   
NDEx NetworkDHRS3
Atlas of Cancer Signalling NetworkDHRS3
Wikipedia pathwaysDHRS3
Orthology - Evolution
OrthoDB9249
GeneTree (enSembl)ENSG00000162496
Phylogenetic Trees/Animal Genes : TreeFamDHRS3
HOVERGENO75911
HOGENOMO75911
Homologs : HomoloGeneDHRS3
Homology/Alignments : Family Browser (UCSC)DHRS3
Gene fusions - Rearrangements
Fusion : MitelmanCAMTA1/DHRS3 [1p36.31/1p36.22]  [t(1;1)(p36;p36)]  
Fusion: TCGACAMTA1 1p36.31 DHRS3 1p36.22 LUSC
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHRS3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHRS3
dbVarDHRS3
ClinVarDHRS3
1000_GenomesDHRS3 
Exome Variant ServerDHRS3
ExAC (Exome Aggregation Consortium)DHRS3 (select the gene name)
Genetic variants : HAPMAP9249
Genomic Variants (DGV)DHRS3 [DGVbeta]
DECIPHERDHRS3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHRS3 
Mutations
ICGC Data PortalDHRS3 
TCGA Data PortalDHRS3 
Broad Tumor PortalDHRS3
OASIS PortalDHRS3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHRS3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHRS3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHRS3
DgiDB (Drug Gene Interaction Database)DHRS3
DoCM (Curated mutations)DHRS3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHRS3 (select a term)
intoGenDHRS3
Cancer3DDHRS3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612830   
Orphanet
MedgenDHRS3
Genetic Testing Registry DHRS3
NextProtO75911 [Medical]
TSGene9249
GENETestsDHRS3
Target ValidationDHRS3
Huge Navigator DHRS3 [HugePedia]
snp3D : Map Gene to Disease9249
BioCentury BCIQDHRS3
ClinGenDHRS3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9249
Chemical/Pharm GKB GenePA134952810
Clinical trialDHRS3
Miscellaneous
canSAR (ICR)DHRS3 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHRS3
EVEXDHRS3
GoPubMedDHRS3
iHOPDHRS3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:05:19 CEST 2017

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