Identity
HGNC
LOCATION
1p36.21
LOCUSID
ALIAS
DD83.1,RDH17,Rsdr1,SDR1,SDR16C1,retSDR1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9249
MIM: 612830
HGNC: 17693
Ensembl: ENSG00000162496
Variants:
dbSNP: 9249
ClinVar: 9249
TCGA: ENSG00000162496
COSMIC: DHRS3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000162496 | ENST00000430996 | Q5SUY4 |
| ENSG00000162496 | ENST00000464917 | A0A087WTY3 |
| ENSG00000162496 | ENST00000616661 | O75911 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36840946 | 2023 | CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis. | 3 |
| 36840946 | 2023 | CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis. | 3 |
| 33902658 | 2021 | Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3. | 7 |
| 33902658 | 2021 | Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3. | 7 |
| 29447006 | 2018 | Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells. | 20 |
| 29689192 | 2018 | Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. | 92 |
| 29447006 | 2018 | Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells. | 20 |
| 29689192 | 2018 | Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development. | 92 |
| 28232491 | 2017 | The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis. | 17 |
| 28371410 | 2017 | New genes associated with rheumatoid arthritis identified by gene expression profiling. | 9 |
| 28232491 | 2017 | The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis. | 17 |
| 28371410 | 2017 | New genes associated with rheumatoid arthritis identified by gene expression profiling. | 9 |
| 24733397 | 2014 | The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis. | 63 |
| 24733397 | 2014 | The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis. | 63 |
| 24005908 | 2013 | The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. | 75 |
Citation
Dessen P
DHRS3 (dehydrogenase/reductase 3)
Atlas Genet Cytogenet Oncol Haematol. 2008-09-01
Online version: http://atlasgeneticsoncology.org/gene/50385/dhrs3
