Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DHRS4L2 (dehydrogenase/reductase (SDR family) member 4 like 2)

Identity

Alias_namesdehydrogenase/reductase (SDR family) member 4 like 2
Alias_symbol (synonym)SDR25C3
Other alias
HGNC (Hugo) DHRS4L2
LocusID (NCBI) 317749
Atlas_Id 62470
Location 14q11.2  [Link to chromosome band 14q11]
Location_base_pair Starts at 24439224 and ends at 24475617 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHRS4L2   19731
Cards
Entrez_Gene (NCBI)DHRS4L2  317749  dehydrogenase/reductase (SDR family) member 4 like 2
AliasesSDR25C3
GeneCards (Weizmann)DHRS4L2
Ensembl hg19 (Hinxton)ENSG00000187630 [Gene_View]  chr14:24439224-24475617 [Contig_View]  DHRS4L2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000187630 [Gene_View]  chr14:24439224-24475617 [Contig_View]  DHRS4L2 [Vega]
ICGC DataPortalENSG00000187630
TCGA cBioPortalDHRS4L2
AceView (NCBI)DHRS4L2
Genatlas (Paris)DHRS4L2
WikiGenes317749
SOURCE (Princeton)DHRS4L2
Genetics Home Reference (NIH)DHRS4L2
Genomic and cartography
GoldenPath hg19 (UCSC)DHRS4L2  -     chr14:24439224-24475617 +  14q11.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)DHRS4L2  -     14q11.2   [Description]    (hg38-Dec_2013)
EnsemblDHRS4L2 - 14q11.2 [CytoView hg19]  DHRS4L2 - 14q11.2 [CytoView hg38]
Mapping of homologs : NCBIDHRS4L2 [Mapview hg19]  DHRS4L2 [Mapview hg38]
OMIM615196   
Gene and transcription
Genbank (Entrez)AI087304 AK021587 AK301373 AY616183 AY920361
RefSeq transcript (Entrez)NM_001193635 NM_001193636 NM_001193637 NM_198083
RefSeq genomic (Entrez)NC_000014 NC_018925 NG_023545 NT_026437 NW_004929393
Consensus coding sequences : CCDS (NCBI)DHRS4L2
Cluster EST : UnigeneHs.743442 [ NCBI ]
CGAP (NCI)Hs.743442
Alternative Splicing GalleryENSG00000187630
Gene ExpressionDHRS4L2 [ NCBI-GEO ]   DHRS4L2 [ EBI - ARRAY_EXPRESS ]   DHRS4L2 [ SEEK ]   DHRS4L2 [ MEM ]
Gene Expression Viewer (FireBrowse)DHRS4L2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)317749
GTEX Portal (Tissue expression)DHRS4L2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6PKH6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6PKH6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6PKH6
Splice isoforms : SwissVarQ6PKH6
Catalytic activity : Enzyme1.1.-.- [ Enzyme-Expasy ]   1.1.-.-1.1.-.- [ IntEnz-EBI ]   1.1.-.- [ BRENDA ]   1.1.-.- [ KEGG ]   
PhosPhoSitePlusQ6PKH6
Domaine pattern : Prosite (Expaxy)ADH_SHORT (PS00061)   
Domains : Interpro (EBI)DH_sc/Rdtase_SDR    DHRS4-like    Glc/ribitol_DH    NAD(P)-bd_dom    Sc_DH/Rdtase_CS   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)DHRS4L2
DMDM Disease mutations317749
Blocks (Seattle)DHRS4L2
SuperfamilyQ6PKH6
Human Protein AtlasENSG00000187630
Peptide AtlasQ6PKH6
HPRD10880
IPIIPI00956591   IPI00937147   IPI00909027   IPI00956447   IPI01012232   IPI01009868   IPI00983235   IPI00984580   IPI00377198   IPI00787015   
Protein Interaction databases
DIP (DOE-UCLA)Q6PKH6
IntAct (EBI)Q6PKH6
FunCoupENSG00000187630
BioGRIDDHRS4L2
STRING (EMBL)DHRS4L2
ZODIACDHRS4L2
Ontologies - Pathways
QuickGOQ6PKH6
Ontology : AmiGOextracellular region  oxidoreductase activity  oxidation-reduction process  
Ontology : EGO-EBIextracellular region  oxidoreductase activity  oxidation-reduction process  
Pathways : KEGGRetinol metabolism   
NDEx NetworkDHRS4L2
Atlas of Cancer Signalling NetworkDHRS4L2
Wikipedia pathwaysDHRS4L2
Orthology - Evolution
OrthoDB317749
GeneTree (enSembl)ENSG00000187630
Phylogenetic Trees/Animal Genes : TreeFamDHRS4L2
HOVERGENQ6PKH6
HOGENOMQ6PKH6
Homologs : HomoloGeneDHRS4L2
Homology/Alignments : Family Browser (UCSC)DHRS4L2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHRS4L2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHRS4L2
dbVarDHRS4L2
ClinVarDHRS4L2
1000_GenomesDHRS4L2 
Exome Variant ServerDHRS4L2
ExAC (Exome Aggregation Consortium)DHRS4L2 (select the gene name)
Genetic variants : HAPMAP317749
Genomic Variants (DGV)DHRS4L2 [DGVbeta]
DECIPHER (Syndromes)14:24439224-24475617  ENSG00000187630
CONAN: Copy Number AnalysisDHRS4L2 
Mutations
ICGC Data PortalDHRS4L2 
TCGA Data PortalDHRS4L2 
Broad Tumor PortalDHRS4L2
OASIS PortalDHRS4L2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHRS4L2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHRS4L2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHRS4L2
DgiDB (Drug Gene Interaction Database)DHRS4L2
DoCM (Curated mutations)DHRS4L2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHRS4L2 (select a term)
intoGenDHRS4L2
Cancer3DDHRS4L2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615196   
Orphanet
MedgenDHRS4L2
Genetic Testing Registry DHRS4L2
NextProtQ6PKH6 [Medical]
TSGene317749
GENETestsDHRS4L2
Huge Navigator DHRS4L2 [HugePedia]
snp3D : Map Gene to Disease317749
BioCentury BCIQDHRS4L2
ClinGenDHRS4L2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD317749
Chemical/Pharm GKB GenePA134930167
Clinical trialDHRS4L2
Miscellaneous
canSAR (ICR)DHRS4L2 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHRS4L2
EVEXDHRS4L2
GoPubMedDHRS4L2
iHOPDHRS4L2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:01:38 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.