DHRS7 (dehydrogenase/reductase 7)

2014-11-01  

Identity

HGNC
LOCATION
14q23.1
LOCUSID
ALIAS
CGI-86,SDR34C1,retDSR4,retSDR4
FUSION GENES

Other Information

Locus ID:

NCBI: 51635
MIM: 612833
HGNC: 21524
Ensembl: ENSG00000100612

Variants:

dbSNP: 51635
ClinVar: 51635
TCGA: ENSG00000100612
COSMIC: DHRS7

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000100612ENST00000216500Q9Y394
ENSG00000100612ENST00000536410Q9Y394
ENSG00000100612ENST00000554101H0YJ66
ENSG00000100612ENST00000557137H0YJE4
ENSG00000100612ENST00000557185Q9Y394
ENSG00000100612ENST00000557326G3V5J0
ENSG00000100612ENST00000557751H0YJR8

Expression (GTEx)

0
50
100
150
200
250
300

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
242467602014Biochemical properties of human dehydrogenase/reductase (SDR family) member 7.3
292163862019An Exome-Wide Association Study Identifies New Susceptibility Loci for Age of Smoking Initiation in African- and European-American Populations.3
264667682016Human DHRS7, promising enzyme in metabolism of steroids and retinoids?1
243161912014Purification and reconstitution of human membrane-bound DHRS7 (SDR34C1) from Sf9 cells.0
284579672017DHRS7 (SDR34C1) - A new player in the regulation of androgen receptor function by inactivation of 5α-dihydrotestosterone?0
286873842017The identification of new substrates of human DHRS7 by molecular modeling and in vitro testing.0

Citation

Dessen P

DHRS7 (dehydrogenase/reductase 7)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/62471/dhrs7