Atlas of Genetics and Cytogenetics in Oncology and Haematology


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DHRS9 (dehydrogenase/reductase 9)

Identity

Alias_namesdehydrogenase/reductase (SDR family) member 9
Alias_symbol (synonym)RDHL
3alpha-HSD
RETSDR8
RDH15
SDR9C4
Other alias3-alpha-HSD
3ALPHA-HSD
RDH-E2
RDH-TBE
RDHTBE
HGNC (Hugo) DHRS9
LocusID (NCBI) 10170
Atlas_Id 55832
Location 2q31.1  [Link to chromosome band 2q31]
Location_base_pair Starts at 169067035 and ends at 169096167 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SPC25 (2q31.1) / DHRS9 (2q31.1)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHRS9   16888
Cards
Entrez_Gene (NCBI)DHRS9  10170  dehydrogenase/reductase 9
Aliases3-alpha-HSD; 3ALPHA-HSD; RDH-E2; RDH-TBE; 
RDH15; RDHL; RDHTBE; RETSDR8; SDR9C4
GeneCards (Weizmann)DHRS9
Ensembl hg19 (Hinxton)ENSG00000073737 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000073737 [Gene_View]  ENSG00000073737 [Sequence]  chr2:169067035-169096167 [Contig_View]  DHRS9 [Vega]
ICGC DataPortalENSG00000073737
TCGA cBioPortalDHRS9
AceView (NCBI)DHRS9
Genatlas (Paris)DHRS9
WikiGenes10170
SOURCE (Princeton)DHRS9
Genetics Home Reference (NIH)DHRS9
Genomic and cartography
GoldenPath hg38 (UCSC)DHRS9  -     chr2:169067035-169096167 +  2q31.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHRS9  -     2q31.1   [Description]    (hg19-Feb_2009)
EnsemblDHRS9 - 2q31.1 [CytoView hg19]  DHRS9 - 2q31.1 [CytoView hg38]
Mapping of homologs : NCBIDHRS9 [Mapview hg19]  DHRS9 [Mapview hg38]
OMIM612131   
Gene and transcription
Genbank (Entrez)AF067174 AF240697 AF240698 AF295380 AF343729
RefSeq transcript (Entrez)NM_001142270 NM_001142271 NM_001289763 NM_005771 NM_199204
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DHRS9
Cluster EST : UnigeneHs.179608 [ NCBI ]
CGAP (NCI)Hs.179608
Alternative Splicing GalleryENSG00000073737
Gene ExpressionDHRS9 [ NCBI-GEO ]   DHRS9 [ EBI - ARRAY_EXPRESS ]   DHRS9 [ SEEK ]   DHRS9 [ MEM ]
Gene Expression Viewer (FireBrowse)DHRS9 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10170
GTEX Portal (Tissue expression)DHRS9
Human Protein AtlasENSG00000073737-DHRS9 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BPW9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BPW9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BPW9
Splice isoforms : SwissVarQ9BPW9
Catalytic activity : Enzyme1.1.-.- [ Enzyme-Expasy ]   1.1.-.-1.1.-.- [ IntEnz-EBI ]   1.1.-.- [ BRENDA ]   1.1.-.- [ KEGG ]   
PhosPhoSitePlusQ9BPW9
Domains : Interpro (EBI)NAD(P)-bd_dom_sf    SDR_fam   
Domain families : Pfam (Sanger)adh_short (PF00106)   
Domain families : Pfam (NCBI)pfam00106   
Conserved Domain (NCBI)DHRS9
DMDM Disease mutations10170
Blocks (Seattle)DHRS9
SuperfamilyQ9BPW9
Human Protein Atlas [tissue]ENSG00000073737-DHRS9 [tissue]
Peptide AtlasQ9BPW9
HPRD09916
IPIIPI01014210   IPI00654615   IPI00654585   IPI00106494   IPI00024782   IPI00926804   
Protein Interaction databases
DIP (DOE-UCLA)Q9BPW9
IntAct (EBI)Q9BPW9
FunCoupENSG00000073737
BioGRIDDHRS9
STRING (EMBL)DHRS9
ZODIACDHRS9
Ontologies - Pathways
QuickGOQ9BPW9
Ontology : AmiGOalcohol dehydrogenase (NAD) activity  retinol dehydrogenase activity  retinol dehydrogenase activity  endoplasmic reticulum membrane  androgen metabolic process  racemase and epimerase activity  integral component of endoplasmic reticulum membrane  epithelial cell differentiation  organelle membrane  progesterone metabolic process  retinol metabolic process  9-cis-retinoic acid biosynthetic process  testosterone dehydrogenase (NAD+) activity  oxidation-reduction process  
Ontology : EGO-EBIalcohol dehydrogenase (NAD) activity  retinol dehydrogenase activity  retinol dehydrogenase activity  endoplasmic reticulum membrane  androgen metabolic process  racemase and epimerase activity  integral component of endoplasmic reticulum membrane  epithelial cell differentiation  organelle membrane  progesterone metabolic process  retinol metabolic process  9-cis-retinoic acid biosynthetic process  testosterone dehydrogenase (NAD+) activity  oxidation-reduction process  
Pathways : KEGGRetinol metabolism   
NDEx NetworkDHRS9
Atlas of Cancer Signalling NetworkDHRS9
Wikipedia pathwaysDHRS9
Orthology - Evolution
OrthoDB10170
GeneTree (enSembl)ENSG00000073737
Phylogenetic Trees/Animal Genes : TreeFamDHRS9
HOVERGENQ9BPW9
HOGENOMQ9BPW9
Homologs : HomoloGeneDHRS9
Homology/Alignments : Family Browser (UCSC)DHRS9
Gene fusions - Rearrangements
Fusion : QuiverDHRS9
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHRS9 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHRS9
dbVarDHRS9
ClinVarDHRS9
1000_GenomesDHRS9 
Exome Variant ServerDHRS9
ExAC (Exome Aggregation Consortium)ENSG00000073737
GNOMAD BrowserENSG00000073737
Varsome BrowserDHRS9
Genetic variants : HAPMAP10170
Genomic Variants (DGV)DHRS9 [DGVbeta]
DECIPHERDHRS9 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHRS9 
Mutations
ICGC Data PortalDHRS9 
TCGA Data PortalDHRS9 
Broad Tumor PortalDHRS9
OASIS PortalDHRS9 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHRS9  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHRS9
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHRS9
DgiDB (Drug Gene Interaction Database)DHRS9
DoCM (Curated mutations)DHRS9 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHRS9 (select a term)
intoGenDHRS9
Cancer3DDHRS9(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM612131   
Orphanet
DisGeNETDHRS9
MedgenDHRS9
Genetic Testing Registry DHRS9
NextProtQ9BPW9 [Medical]
TSGene10170
GENETestsDHRS9
Target ValidationDHRS9
Huge Navigator DHRS9 [HugePedia]
snp3D : Map Gene to Disease10170
BioCentury BCIQDHRS9
ClinGenDHRS9
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10170
Chemical/Pharm GKB GenePA134913654
Clinical trialDHRS9
Miscellaneous
canSAR (ICR)DHRS9 (select the gene name)
Probes
Litterature
PubMed19 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHRS9
EVEXDHRS9
GoPubMedDHRS9
iHOPDHRS9
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 6 11:02:22 CET 2018

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