Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DHX15 (DEAH-box helicase 15)

Identity

Alias_namesDDX15
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 15
DEAH (Asp-Glu-Ala-His) box polypeptide 15
DEAH (Asp-Glu-Ala-His) box helicase 15
Alias_symbol (synonym)HRH2
DBP1
PRP43
PrPp43p
PRPF43
Other alias
HGNC (Hugo) DHX15
LocusID (NCBI) 1665
Atlas_Id 62477
Location 4p15.2  [Link to chromosome band 4p15]
Location_base_pair Starts at 24527465 and ends at 24584561 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
DHX15 (4p15.2) / RBPJ (4p15.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHX15   2738
Cards
Entrez_Gene (NCBI)DHX15  1665  DEAH-box helicase 15
AliasesDBP1; DDX15; HRH2; PRP43; 
PRPF43; PrPp43p
GeneCards (Weizmann)DHX15
Ensembl hg19 (Hinxton)ENSG00000109606 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000109606 [Gene_View]  chr4:24527465-24584561 [Contig_View]  DHX15 [Vega]
ICGC DataPortalENSG00000109606
TCGA cBioPortalDHX15
AceView (NCBI)DHX15
Genatlas (Paris)DHX15
WikiGenes1665
SOURCE (Princeton)DHX15
Genetics Home Reference (NIH)DHX15
Genomic and cartography
GoldenPath hg38 (UCSC)DHX15  -     chr4:24527465-24584561 -  4p15.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHX15  -     4p15.2   [Description]    (hg19-Feb_2009)
EnsemblDHX15 - 4p15.2 [CytoView hg19]  DHX15 - 4p15.2 [CytoView hg38]
Mapping of homologs : NCBIDHX15 [Mapview hg19]  DHX15 [Mapview hg38]
OMIM603403   
Gene and transcription
Genbank (Entrez)AA771922 AB001636 AF279891 AK054614 AK055898
RefSeq transcript (Entrez)NM_001358
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)DHX15
Cluster EST : UnigeneHs.696074 [ NCBI ]
CGAP (NCI)Hs.696074
Alternative Splicing GalleryENSG00000109606
Gene ExpressionDHX15 [ NCBI-GEO ]   DHX15 [ EBI - ARRAY_EXPRESS ]   DHX15 [ SEEK ]   DHX15 [ MEM ]
Gene Expression Viewer (FireBrowse)DHX15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)1665
GTEX Portal (Tissue expression)DHX15
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43143   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43143  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43143
Splice isoforms : SwissVarO43143
PhosPhoSitePlusO43143
Domaine pattern : Prosite (Expaxy)DEAH_ATP_HELICASE (PS00690)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DNA/RNA_helicase_DEAH_CS    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)DEAD (PF00270)    HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam00270    pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
Conserved Domain (NCBI)DHX15
DMDM Disease mutations1665
Blocks (Seattle)DHX15
SuperfamilyO43143
Human Protein AtlasENSG00000109606
Peptide AtlasO43143
HPRD04553
IPIIPI00396435   IPI01015591   
Protein Interaction databases
DIP (DOE-UCLA)O43143
IntAct (EBI)O43143
FunCoupENSG00000109606
BioGRIDDHX15
STRING (EMBL)DHX15
ZODIACDHX15
Ontologies - Pathways
QuickGOO43143
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  RNA helicase activity  double-stranded RNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  U12-type spliceosomal complex  nucleolus  cytoplasm  mRNA processing  RNA splicing  response to toxic substance  nuclear speck  response to alkaloid  U2-type post-mRNA release spliceosomal complex  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  RNA helicase activity  double-stranded RNA binding  ATP-dependent RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  U12-type spliceosomal complex  nucleolus  cytoplasm  mRNA processing  RNA splicing  response to toxic substance  nuclear speck  response to alkaloid  U2-type post-mRNA release spliceosomal complex  
Pathways : KEGGSpliceosome   
NDEx NetworkDHX15
Atlas of Cancer Signalling NetworkDHX15
Wikipedia pathwaysDHX15
Orthology - Evolution
OrthoDB1665
GeneTree (enSembl)ENSG00000109606
Phylogenetic Trees/Animal Genes : TreeFamDHX15
HOVERGENO43143
HOGENOMO43143
Homologs : HomoloGeneDHX15
Homology/Alignments : Family Browser (UCSC)DHX15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHX15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX15
dbVarDHX15
ClinVarDHX15
1000_GenomesDHX15 
Exome Variant ServerDHX15
ExAC (Exome Aggregation Consortium)DHX15 (select the gene name)
Genetic variants : HAPMAP1665
Genomic Variants (DGV)DHX15 [DGVbeta]
DECIPHERDHX15 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHX15 
Mutations
ICGC Data PortalDHX15 
TCGA Data PortalDHX15 
Broad Tumor PortalDHX15
OASIS PortalDHX15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHX15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHX15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHX15
DgiDB (Drug Gene Interaction Database)DHX15
DoCM (Curated mutations)DHX15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHX15 (select a term)
intoGenDHX15
Cancer3DDHX15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603403   
Orphanet
MedgenDHX15
Genetic Testing Registry DHX15
NextProtO43143 [Medical]
TSGene1665
GENETestsDHX15
Target ValidationDHX15
Huge Navigator DHX15 [HugePedia]
snp3D : Map Gene to Disease1665
BioCentury BCIQDHX15
ClinGenDHX15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD1665
Chemical/Pharm GKB GenePA27204
Clinical trialDHX15
Miscellaneous
canSAR (ICR)DHX15 (select the gene name)
Probes
Litterature
PubMed79 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHX15
EVEXDHX15
GoPubMedDHX15
iHOPDHX15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Mon Sep 18 13:06:15 CEST 2017

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.