Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

DHX16 (DEAH-box helicase 16)

Identity

Alias_namesDDX16
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
Alias_symbol (synonym)DBP2
Prp2
PRPF2
Other aliasPRO2014
PRP8
HGNC (Hugo) DHX16
LocusID (NCBI) 8449
Atlas_Id 46670
Location 6p21.33  [Link to chromosome band 6p21]
Location_base_pair Starts at 30653119 and ends at 30673053 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)DHX16   2739
Cards
Entrez_Gene (NCBI)DHX16  8449  DEAH-box helicase 16
AliasesDBP2; DDX16; PRO2014; PRP8; 
PRPF2; Prp2
GeneCards (Weizmann)DHX16
Ensembl hg19 (Hinxton)ENSG00000204560 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000204560 [Gene_View]  ENSG00000204560 [Sequence]  chr6:30653119-30673053 [Contig_View]  DHX16 [Vega]
ICGC DataPortalENSG00000204560
TCGA cBioPortalDHX16
AceView (NCBI)DHX16
Genatlas (Paris)DHX16
WikiGenes8449
SOURCE (Princeton)DHX16
Genetics Home Reference (NIH)DHX16
Genomic and cartography
GoldenPath hg38 (UCSC)DHX16  -     chr6:30653119-30673053 -  6p21.33   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)DHX16  -     6p21.33   [Description]    (hg19-Feb_2009)
EnsemblDHX16 - 6p21.33 [CytoView hg19]  DHX16 - 6p21.33 [CytoView hg38]
Mapping of homologs : NCBIDHX16 [Mapview hg19]  DHX16 [Mapview hg38]
OMIM603405   
Gene and transcription
Genbank (Entrez)AB001601 AF119860 AK302721 AK312264 BC002789
RefSeq transcript (Entrez)NM_001164239 NM_001363515 NM_003587
RefSeq genomic (Entrez)NC_000006 NT_113891 NT_167244 NT_167245 NT_167246 NT_167247 NT_167248 NT_167249
Consensus coding sequences : CCDS (NCBI)DHX16
Cluster EST : UnigeneHs.485060 [ NCBI ]
CGAP (NCI)Hs.485060
Alternative Splicing GalleryENSG00000204560
Gene ExpressionDHX16 [ NCBI-GEO ]   DHX16 [ EBI - ARRAY_EXPRESS ]   DHX16 [ SEEK ]   DHX16 [ MEM ]
Gene Expression Viewer (FireBrowse)DHX16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8449
GTEX Portal (Tissue expression)DHX16
Human Protein AtlasENSG00000204560-DHX16 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60231   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60231  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60231
Splice isoforms : SwissVarO60231
Catalytic activity : Enzyme3.6.4.13 [ Enzyme-Expasy ]   3.6.4.133.6.4.13 [ IntEnz-EBI ]   3.6.4.13 [ BRENDA ]   3.6.4.13 [ KEGG ]   
PhosPhoSitePlusO60231
Domaine pattern : Prosite (Expaxy)DEAH_ATP_HELICASE (PS00690)    HELICASE_ATP_BIND_1 (PS51192)    HELICASE_CTER (PS51194)   
Domains : Interpro (EBI)DEAD/DEAH_box_helicase_dom    DNA/RNA_helicase_DEAH_CS    DUF1605    Helicase-assoc_dom    Helicase_ATP-bd    Helicase_C    P-loop_NTPase   
Domain families : Pfam (Sanger)DEAD (PF00270)    HA2 (PF04408)    Helicase_C (PF00271)    OB_NTP_bind (PF07717)   
Domain families : Pfam (NCBI)pfam00270    pfam04408    pfam00271    pfam07717   
Domain families : Smart (EMBL)DEXDc (SM00487)  HA2 (SM00847)  HELICc (SM00490)  
Conserved Domain (NCBI)DHX16
DMDM Disease mutations8449
Blocks (Seattle)DHX16
SuperfamilyO60231
Human Protein Atlas [tissue]ENSG00000204560-DHX16 [tissue]
Peptide AtlasO60231
HPRD04555
IPIIPI00552073   IPI00789517   IPI00297178   IPI00292510   IPI00644906   IPI00894081   IPI00894447   
Protein Interaction databases
DIP (DOE-UCLA)O60231
IntAct (EBI)O60231
FunCoupENSG00000204560
BioGRIDDHX16
STRING (EMBL)DHX16
ZODIACDHX16
Ontologies - Pathways
QuickGOO60231
Ontology : AmiGOmRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  RNA binding  RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  spliceosomal complex  spliceosomal complex  RNA splicing  ATPase activity  ATP-dependent 3'-5' RNA helicase activity  
Ontology : EGO-EBImRNA splicing, via spliceosome  mRNA splicing, via spliceosome  RNA binding  RNA binding  RNA helicase activity  protein binding  ATP binding  nucleus  nucleoplasm  nucleoplasm  spliceosomal complex  spliceosomal complex  RNA splicing  ATPase activity  ATP-dependent 3'-5' RNA helicase activity  
Pathways : KEGGSpliceosome   
NDEx NetworkDHX16
Atlas of Cancer Signalling NetworkDHX16
Wikipedia pathwaysDHX16
Orthology - Evolution
OrthoDB8449
GeneTree (enSembl)ENSG00000204560
Phylogenetic Trees/Animal Genes : TreeFamDHX16
HOVERGENO60231
HOGENOMO60231
Homologs : HomoloGeneDHX16
Homology/Alignments : Family Browser (UCSC)DHX16
Gene fusions - Rearrangements
Fusion : QuiverDHX16
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerDHX16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)DHX16
dbVarDHX16
ClinVarDHX16
1000_GenomesDHX16 
Exome Variant ServerDHX16
ExAC (Exome Aggregation Consortium)ENSG00000204560
GNOMAD BrowserENSG00000204560
Varsome BrowserDHX16
Genetic variants : HAPMAP8449
Genomic Variants (DGV)DHX16 [DGVbeta]
DECIPHERDHX16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisDHX16 
Mutations
ICGC Data PortalDHX16 
TCGA Data PortalDHX16 
Broad Tumor PortalDHX16
OASIS PortalDHX16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICDHX16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDDHX16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch DHX16
DgiDB (Drug Gene Interaction Database)DHX16
DoCM (Curated mutations)DHX16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)DHX16 (select a term)
intoGenDHX16
Cancer3DDHX16(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603405   
Orphanet
DisGeNETDHX16
MedgenDHX16
Genetic Testing Registry DHX16
NextProtO60231 [Medical]
TSGene8449
GENETestsDHX16
Target ValidationDHX16
Huge Navigator DHX16 [HugePedia]
snp3D : Map Gene to Disease8449
BioCentury BCIQDHX16
ClinGenDHX16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8449
Chemical/Pharm GKB GenePA27205
Clinical trialDHX16
Miscellaneous
canSAR (ICR)DHX16 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineDHX16
EVEXDHX16
GoPubMedDHX16
iHOPDHX16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:02:23 CET 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.